Synthetic curcuminoids modulate the arachidonic acid metabolism of human platelet 12-lipoxygenase and reduce sprout formation of human endothelial cells

2006 ◽  
Vol 5 (5) ◽  
pp. 1371-1382 ◽  
Author(s):  
Jerzy Jankun ◽  
Ansari M. Aleem ◽  
Sylvia Malgorzewicz ◽  
Maria Szkudlarek ◽  
Maria I. Zavodszky ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Arachidonic Acid ◽  
Acid Metabolism ◽  
Human Platelet ◽  
Arachidonic Acid Metabolism ◽  
Human Endothelial Cells ◽  
12 Lipoxygenase ◽  
Sprout Formation

Characteristics of arachidonic acid metabolism of human endothelial cells in culture

1990 ◽  
Vol 3 (1) ◽  
pp. 21-29 ◽  
Author(s):  
Vincenta Martinez-Sales ◽  
Maria Jos� Gomez-Lech�n ◽  
Juan Gilabert
Keyword(s):  
Endothelial Cells ◽  
Arachidonic Acid ◽  
Acid Metabolism ◽  
Arachidonic Acid Metabolism ◽  
Human Endothelial Cells ◽  
Cells In Culture

scholarly journals The influence of albumin and calcium on human platelet arachidonic acid metabolism

Blood ◽  
1980 ◽  
Vol 55 (3) ◽  
pp. 418-423 ◽  
Author(s):  
MJ Stuart ◽  
JM Gerrard ◽  
JG White
Keyword(s):  
Arachidonic Acid ◽  
Acid Metabolism ◽  
Human Platelet ◽  
Arachidonic Acid Metabolism ◽  
Albumin Concentration ◽  
Arachidonic Acid Release ◽  
Acid Release ◽  
External Calcium ◽  
Platelet Thromboxane

Abstract The effects of in vitro changes in calcium and albumin on human platelet arachidonic acid metabolism were evaluated. Hypoalbuminemia enhanced the conversion of released 14C-arachidonic acid from prelabeled platelet phospholipids to the metabolites of the platelet cyclooxygenase and lipoxygenase pathways. This effect was, however, associated with a decreased release of arachidonic acid in the presence of hypoalbuminemia, such that the overall conversion of released 14C- arachidonic acid to platelet thromboxane B2 was similar in the presence of physiologic albumin concentration (3.5 g/dl) or at decreased albumin concentrations of 0.7 and 0.0 g/dl. External calcium was shown to be important for optimal platelet arachidonic acid release, with maximal release occurring at 1 mM calcium.

ARACHIDONIC ACID METABOLISM IN ENDOTHELIAL CELLS AND PLATELETS

1982 ◽  
Vol 401 (1 Endothelium) ◽  
pp. 195-202 ◽  
Author(s):  
A. J. Marcus ◽  
M. J. Broekman ◽  
B. B. Weksler ◽  
E. A. Jaffe ◽  
L. B. Safier ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Arachidonic Acid ◽  
Acid Metabolism ◽  
Arachidonic Acid Metabolism

Arachidonic acid metabolism in cultured aortic endothelial cells

1985 ◽  
Vol 34 (1) ◽  
pp. 119-123 ◽  
Author(s):  
A.Richard Whorton ◽  
James B. Collawn ◽  
Malcolm E. Montgomery ◽  
Stephen L. Young ◽  
Richard S. Kent
Keyword(s):  
Endothelial Cells ◽  
Arachidonic Acid ◽  
Acid Metabolism ◽  
Arachidonic Acid Metabolism ◽  
Aortic Endothelial Cells ◽  
Aortic Endothelial

Asymmetry of arachidonic acid metabolism in the phospholipids of the human platelet membrane as studied with purified phospholipases

1982 ◽  
Vol 693 (2) ◽  
pp. 451-460 ◽  
Author(s):  
Monique Plantavid ◽  
Bertrand Pierre Perret ◽  
Hugues Chap ◽  
Marie-Françoise Simon ◽  
Louis Douste-Blazy
Keyword(s):  
Arachidonic Acid ◽  
Acid Metabolism ◽  
Human Platelet ◽  
Arachidonic Acid Metabolism ◽  
Platelet Membrane
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