scholarly journals Role of Dimerized C16orf74 in Aggressive Pancreatic Cancer: A Novel Therapeutic Target

2019 ◽  
Vol 19 (1) ◽  
pp. 187-198 ◽  
Author(s):  
Toshihiro Kushibiki ◽  
Toru Nakamura ◽  
Masumi Tsuda ◽  
Takahiro Tsuchikawa ◽  
Koji Hontani ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Therapeutic Target ◽  
Novel Therapeutic

Molecular Interactions of α-Synuclein, Mitochondria, and Cellular Degradation Pathways in Parkinson's Disease

2020 ◽  
pp. 212-234
Author(s):  
Mansi Verma ◽  
Sujata Basu ◽  
Manisha Singh ◽  
Rachana R. ◽  
Simrat Kaur ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Molecular Interactions ◽  
Therapeutic Target ◽  
Molecular Mechanisms ◽  
Degradation Pathways ◽  
Functional Changes ◽  
The World ◽  
Novel Therapeutic

Parkinson's disease (PD) has been reported to be the most common neurodegenerative diseases all over the world. Several proteins are associated and responsible for causing PD. One such protein is α-synuclein. This chapter discusses the role of α-synuclein in PD. Various genetic and epigenetic factors, which cause structural and functional changes for α-synuclein, have been described. Several molecular mechanisms, which are involved in regulating mitochondrial and lysosomal related pathways and are linked to α-synuclein, have been discussed in detail. The knowledge gathered is further discussed in terms of using α-synuclein as a diagnostic marker for PD and as a novel therapeutic target for the same.

scholarly journals The Role of DLLs in Cancer: A Novel Therapeutic Target

2020 ◽  
Vol Volume 13 ◽  
pp. 3881-3901 ◽  
Author(s):  
Meng-Xi Xiu ◽  
Yuan-Meng Liu ◽  
Bo-hai Kuang
Keyword(s):  
Therapeutic Target ◽  
Novel Therapeutic

scholarly journals ANO9/TMEM16J promotes tumourigenesis via EGFR and is a novel therapeutic target for pancreatic cancer

2017 ◽  
Vol 117 (12) ◽  
pp. 1798-1809 ◽  
Author(s):  
Ikhyun Jun ◽  
Hyung Soon Park ◽  
He Piao ◽  
Jung Woo Han ◽  
Min Ji An ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Therapeutic Target ◽  
Novel Therapeutic

scholarly journals Depleted Tumor Suppressor miR-107 in Plasma Relates to Tumor Progression and Is a Novel Therapeutic Target in Pancreatic Cancer

2017 ◽  
Vol 225 (4) ◽  
pp. e120 ◽  
Author(s):  
Taisuke Imamura ◽  
Shuhei Komatsu ◽  
Daisuke Ichikawa ◽  
Wataru Okajima ◽  
Takuma Ohashi ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Tumor Suppressor ◽  
Tumor Progression ◽  
Therapeutic Target ◽  
Novel Therapeutic

scholarly journals Depleted tumor suppressor miR-107 in plasma relates to tumor progression and is a novel therapeutic target in pancreatic cancer

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Taisuke Imamura ◽  
Shuhei Komatsu ◽  
Daisuke Ichikawa ◽  
Mahito Miyamae ◽  
Wataru Okajima ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Tumor Suppressor ◽  
Tumor Progression ◽  
Therapeutic Target ◽  
Novel Therapeutic

Update on the role of autophagy in systemic lupus erythematosus: A novel therapeutic target

2015 ◽  
Vol 71 ◽  
pp. 190-193 ◽  
Author(s):  
Qingjun Pan ◽  
Caina Gao ◽  
Yanwen Chen ◽  
Yongmin Feng ◽  
Wei Jing Liu ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Therapeutic Target ◽  
Systemic Lupus ◽  
Novel Therapeutic
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