Abstract 1506: Changes in the expression profile of microRNAs and their predicted targets in fibroblasts associated with breast carcinoma compared to fibroblasts from normal breast tissue.

2013 ◽  
Author(s):  
Simone V. Costa ◽  
Rosimeire A. Roela ◽  
Fatima S. Pasini ◽  
Maria L H Katayama ◽  
Tatiane K. F. Mazzotti ◽  
...  
Keyword(s):  
Breast Carcinoma ◽  
Expression Profile ◽  
Breast Tissue ◽  
Normal Breast Tissue ◽  
Normal Breast

Localization of hyaluronan in normal breast tissue, radial scar, and tubular breast carcinoma

1993 ◽  
Vol 24 (12) ◽  
pp. 1294-1297 ◽  
Author(s):  
Manuel de la Torre ◽  
Alvin F. Wells ◽  
Jonas Bergh ◽  
Anders Lindgren
Keyword(s):  
Breast Carcinoma ◽  
Breast Tissue ◽  
Normal Breast Tissue ◽  
Normal Breast ◽  
Radial Scar ◽  
Tubular Breast

DESMOLASE ACTIVITY OF NORMAL AND MALIGNANT HUMAN BREAST TISSUE

1969 ◽  
Vol 44 (1) ◽  
pp. 69-77 ◽  
Author(s):  
J. B. ADAMS ◽  
M. S. F. WONG
Keyword(s):  
Breast Carcinoma ◽  
Breast Tissue ◽  
Normal Breast Tissue ◽  
Radical Mastectomy ◽  
Normal Breast ◽  
Acetone Powder ◽  
Human Breast ◽  
Carcinoma Tissue ◽  
Mastectomy Specimen ◽  
Powder Fraction

SUMMARY [4-14C]Cholesterol was cleaved to pregnenolone and progesterone by a washed particulate fraction isolated from involved lymph nodes obtained from a radical mastectomy specimen. Difficulties were experienced in isolating subcellular fractions from primary breast tumours and normal breast tissue. However, an acetone powder fraction, obtained from normal tissue derived from a radical mastectomy specimen, yielded pregnenolone from [4-14C]cholesterol. [7α-3H]17α-Hydroxyprogesterone was converted to androstenedione and to 17α,20α-dihydroxypregn-4-en-3-one and its 17α,20β-epimer by homogenates of secondary breast carcinoma tissue and normal breast tissue obtained from radical mastectomy specimens. These results, in conjunction with those obtained previously (Adams & Wong, 1968a), show that human breast carcinoma tissue contains the enzymes necessary to convert cholesterol to androgens and oestrogens.

Sign in / Sign up

Export Citation Format

Share Document