Abstract 2326: LTX-315, an oncolytic peptide, increases anticancer immunity mediated by CTLA4 blockade in an interleukin-2 receptor beta-chain-dependent manner

SH2-dependent association of phosphatidylinositol 3'-kinase 85-kDa regulatory subunit with the interleukin-2 receptor beta chain.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)37552-x ◽

1994 ◽

Vol 269 (8) ◽

pp. 5937-5943

Author(s):

K.E. Truitt ◽

G.B. Mills ◽

C.W. Turck ◽

J.B. Imboden

Keyword(s):

Interleukin 2 ◽

Regulatory Subunit ◽

Beta Chain ◽

Phosphatidylinositol 3 Kinase ◽

Interleukin 2 Receptor ◽

Receptor Beta ◽

Phosphatidylinositol 3

Identification of three adjacent amino acids of interleukin-2 receptor beta chain which control the affinity and the specificity of the interaction with interleukin-2.

The EMBO Journal ◽

10.1002/j.1460-2075.1992.tb05262.x ◽

1992 ◽

Vol 11 (6) ◽

pp. 2047-2053 ◽

Cited By ~ 25

Author(s):

J.L. Imler ◽

A. Miyajima ◽

G. Zurawski

Keyword(s):

Amino Acids ◽

Interleukin 2 ◽

Beta Chain ◽

Interleukin 2 Receptor ◽

Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's

Science ◽

10.1126/science.2785715 ◽

1989 ◽

Vol 244 (4904) ◽

pp. 551-556 ◽

Cited By ~ 432

Author(s):

M Hatakeyama ◽

M Tsudo ◽

S Minamoto ◽

T Kono ◽

T Doi ◽

...

Keyword(s):

Interleukin 2 ◽

Chain Gene ◽

Beta Chain ◽

Interleukin 2 Receptor ◽

Human interleukin 2 receptor beta-chain gene: chromosomal localization and identification of 5' regulatory sequences.

10.1073/pnas.87.9.3440 ◽

1990 ◽

Vol 87 (9) ◽

pp. 3440-3444 ◽

Cited By ~ 36

Author(s):

J. R. Gnarra ◽

H. Otani ◽

M. G. Wang ◽

O. W. McBride ◽

M. Sharon ◽

...

Keyword(s):

Chromosomal Localization ◽

Interleukin 2 ◽

Chain Gene ◽

Regulatory Sequences ◽

Beta Chain ◽

Interleukin 2 Receptor ◽

c-fos gene induction by interleukin 2: identification of the critical cytoplasmic regions within the interleukin 2 receptor beta chain.

10.1073/pnas.89.6.2022 ◽

1992 ◽

Vol 89 (6) ◽

pp. 2022-2026 ◽

Cited By ~ 31

Author(s):

M. Hatakeyama ◽

A. Kawahara ◽

H. Mori ◽

H. Shibuya ◽

T. Taniguchi

Keyword(s):

Interleukin 2 ◽

Gene Induction ◽

Beta Chain ◽

Interleukin 2 Receptor ◽

Interleukin-2 receptor beta chain locus rearrangement in a T-cell acute lymphoblastic leukemia

Pathologie Biologie ◽

10.1016/j.patbio.2006.04.004 ◽

2007 ◽

Vol 55 (1) ◽

pp. 56-58 ◽

Cited By ~ 1

Author(s):

R. Berger ◽

O.A. Bernard

Keyword(s):

Acute Lymphoblastic Leukemia ◽

T Cell ◽

Lymphoblastic Leukemia ◽

Interleukin 2 ◽

Beta Chain ◽

Interleukin 2 Receptor ◽

Chain Locus ◽

Cell Acute Lymphoblastic Leukemia ◽

Characterization of the interleukin 2 receptor beta chain using three distinct monoclonal antibodies.

10.1073/pnas.86.6.1982 ◽

1989 ◽

Vol 86 (6) ◽

pp. 1982-1986 ◽

Cited By ~ 105

Author(s):

M. Tsudo ◽

F. Kitamura ◽

M. Miyasaka

Keyword(s):

Monoclonal Antibodies ◽

Interleukin 2 ◽

Beta Chain ◽

Interleukin 2 Receptor ◽

Activation of Stat5 by interleukin 2 requires a carboxyl-terminal region of the interleukin 2 receptor beta chain but is not essential for the proliferative signal transmission.

10.1073/pnas.92.12.5482 ◽

1995 ◽

Vol 92 (12) ◽

pp. 5482-5486 ◽

Cited By ~ 116

Author(s):

H. Fujii ◽

Y. Nakagawa ◽

U. Schindler ◽

A. Kawahara ◽

H. Mori ◽

...

Keyword(s):

Signal Transmission ◽

Interleukin 2 ◽

Terminal Region ◽

Beta Chain ◽

Interleukin 2 Receptor ◽

Carboxyl Terminal ◽

Receptor Beta ◽

Proliferative Signal

The serine-rich cytoplasmic domain of the interleukin-2 receptor beta chain is essential for interleukin-2-dependent tyrosine protein kinase and phosphatidylinositol-3-kinase activation.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)53315-9 ◽

1993 ◽

Vol 268 (9) ◽

pp. 6765-6770

Author(s):

I. Merida ◽

P. Williamson ◽

W.A. Kuziel ◽

W.C. Greene ◽

G.N. Gaulton

Keyword(s):

Protein Kinase ◽

Interleukin 2 ◽

Cytoplasmic Domain ◽

Beta Chain ◽

Phosphatidylinositol 3 Kinase ◽

Kinase Activation ◽

Interleukin 2 Receptor ◽

Tyrosine Protein Kinase ◽

Receptor Beta ◽

Phosphatidylinositol 3

Synthetic peptides as putative therapeutic agents in transplantation medicine: application of PEPSCAN to the identification of functional sequences in the extracellular domain of the interleukin-2 receptor beta chain (IL-2Rβ)

Journal of Immunological Methods ◽

10.1016/s0022-1759(00)00212-x ◽

2000 ◽

Vol 241 (1-2) ◽

pp. 83-95 ◽

Cited By ~ 1

Author(s):

Helen Dionyssopoulou ◽

Athanasia Mouzaki ◽

Jerry Slootstra ◽

Wouter Puijk ◽

Rob Meloen ◽

...

Keyword(s):

Synthetic Peptides ◽

Interleukin 2 ◽

Extracellular Domain ◽

Therapeutic Agents ◽

Beta Chain ◽

Transplantation Medicine ◽

Interleukin 2 Receptor ◽

Receptor Beta ◽

Medicine Application