Abstract 4711: Novel mechanism involved in the regulation ofoncogenic Axl receptor tyrosine kinase in cancer

AXL receptor tyrosine kinase (AXL; UFO)

Science-Business eXchange ◽

10.1038/scibx.2012.725 ◽

2012 ◽

Vol 5 (28) ◽

pp. 725-725

Keyword(s):

Tyrosine Kinase ◽

564 Co-expression of Axl-receptor tyrosine kinase and its ligand GAS6 in non-small cell lung cancer cell lines

Lung Cancer ◽

10.1016/s0169-5002(97)89944-8 ◽

1997 ◽

Vol 18 ◽

pp. 145

Author(s):

A. Wimmel ◽

D. Glitz ◽

K. Havemann ◽

M. Schuermann

Keyword(s):

Lung Cancer ◽

Tyrosine Kinase ◽

Small Cell Lung Cancer ◽

Cell Lines ◽

Cancer Cell ◽

Small Cell ◽

Lung Cancer Cell ◽

Small Cell Lung ◽

Targeting of the AXL receptor tyrosine kinase by small molecule inhibitor leads to AXL cell surface accumulation by impairing the ubiquitin-dependent receptor degradation

Cell Communication and Signaling ◽

10.1186/s12964-019-0377-8 ◽

2019 ◽

Vol 17 (1) ◽

Cited By ~ 4

Author(s):

Markus Lauter ◽

Anja Weber ◽

Robert Torka

Keyword(s):

Cell Surface ◽

Tyrosine Kinase ◽

Small Molecule ◽

Small Molecule Inhibitor ◽

Molecule Inhibitor ◽

Molecular Mechanism of 17-Allylamino-17-demethoxygeldanamycin (17-AAG)-induced AXL Receptor Tyrosine Kinase Degradation

Journal of Biological Chemistry ◽

10.1074/jbc.m112.439422 ◽

2013 ◽

Vol 288 (24) ◽

pp. 17481-17494 ◽

Cited By ~ 32

Author(s):

Gnana Prakasam Krishnamoorthy ◽

Teresa Guida ◽

Luigi Alfano ◽

Elvira Avilla ◽

Massimo Santoro ◽

...

Keyword(s):

Tyrosine Kinase ◽

Molecular Mechanism ◽

The Role of Axl Receptor Tyrosine Kinase in Tumor Cell Plasticity and Therapy Resistance

Biomarkers of the Tumor Microenvironment ◽

10.1007/978-3-319-39147-2_15 ◽

2017 ◽

pp. 351-376 ◽

Cited By ~ 1

Author(s):

Kjersti T. Davidsen ◽

Gry S. Haaland ◽

Maria K. Lie ◽

James B. Lorens ◽

Agnete S. T. Engelsen

Keyword(s):

Tyrosine Kinase ◽

Tumor Cell ◽

Therapy Resistance ◽

Cell Plasticity ◽

Tumor Cell Plasticity ◽

Abstract 3969: TP-0903, a potent AXL receptor tyrosine kinase inhibitor, enhances the activity of anti-PD-1 therapy in a metastatic preclinical syngeneic model of breast cancer

10.1158/1538-7445.sabcs18-3969 ◽

2019 ◽

Author(s):

Yuka Kumagai ◽

Jun Oishi ◽

Megumi Nakamura ◽

Jason M. Foulks ◽

Clifford J. Whatcott ◽

...

Keyword(s):

Breast Cancer ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Kinase Inhibitor ◽

Receptor Tyrosine Kinase Inhibitor ◽

Axl Receptor Tyrosine Kinase ◽

Syngeneic Model

Discovery and characterization of potent and selective AXL receptor tyrosine kinase inhibitors for cancer therapy

European Journal of Cancer ◽

10.1016/s0959-8049(20)31175-8 ◽

2020 ◽

Vol 138 ◽

pp. S38-S39

Author(s):

D. Miles ◽

Y. Chen ◽

S.L. Paprcka ◽

C.N. Foley ◽

R. Grange ◽

...

Keyword(s):

Cancer Therapy ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Receptor Tyrosine Kinase Inhibitors

Kinase Inhibitors ◽

Axl Receptor Tyrosine Kinase ◽

Axl receptor tyrosine kinase stimulated by the vitamin K-dependent protein encoded by growth-arrest-specific gene 6

Nature ◽

10.1038/373623a0 ◽

1995 ◽

Vol 373 (6515) ◽

pp. 623-626 ◽

Cited By ~ 309

Author(s):

Brian C. Varnum ◽

Cynthia Young ◽

Gary Elliott ◽

Andy Garcia ◽

Timothy D. Bartley ◽

...

Keyword(s):

Tyrosine Kinase ◽

Vitamin K ◽

Growth Arrest ◽

Specific Gene ◽

Dependent Protein ◽

Intracellular signaling of the Ufo/Axl receptor tyrosine kinase is mediated mainly by a multi-substrate docking-site

Oncogene ◽

10.1038/sj.onc.1201123 ◽

1997 ◽

Vol 14 (22) ◽

pp. 2619-2631 ◽

Cited By ~ 97

Author(s):

Jürgen Braunger ◽

Lothar Schleithoff ◽

Ansgar S Schulz ◽

Heidi Kessler ◽

Reiner Lammers ◽

...

Keyword(s):

Tyrosine Kinase ◽

Intracellular Signaling ◽

Docking Site ◽

Substrate Docking ◽

Regulation of Axl receptor tyrosine kinase expression by miR-34a and miR-199a/b in solid cancer

Oncogene ◽

10.1038/onc.2011.13 ◽

2011 ◽

Vol 30 (25) ◽

pp. 2888-2899 ◽

Cited By ~ 158

Author(s):

G Mudduluru ◽

P Ceppi ◽

R Kumarswamy ◽

G V Scagliotti ◽

M Papotti ◽

...

Keyword(s):

Tyrosine Kinase ◽

Solid Cancer ◽

Axl Receptor Tyrosine Kinase ◽

Kinase Expression