Haemopoietic Cell Transplantation of Patients with a History of Deep or Invasive Fungal Infection during Prophylaxis with Liposomal Amphotericin B

2005 ◽  
Vol 113 (2) ◽  
pp. 104-108 ◽  
Author(s):  
William H. Krüger ◽  
Bettina Rüssmann ◽  
Maike de Wit ◽  
Nicolaus Kröger ◽  
Helmut Renges ◽  
...  
Keyword(s):  
Fungal Infection ◽  
Amphotericin B ◽  
Cell Transplantation ◽  
Invasive Fungal Infection ◽  
Liposomal Amphotericin ◽  
Liposomal Amphotericin B ◽  
History Of

An epidemic of invasive fungal infection in a stem cell transplant unit; response to high-dose liposomal amphotericin B

2004 ◽  
Vol 5 (6) ◽  
pp. 548-551 ◽  
Author(s):  
Clodagh Ryan ◽  
Siobhan McNicholsan ◽  
Brian O'Connell ◽  
Stephanie Forde ◽  
Mary Keoghan ◽  
...  
Keyword(s):  
Stem Cell ◽  
Fungal Infection ◽  
Amphotericin B ◽  
Invasive Fungal Infection ◽  
Liposomal Amphotericin ◽  
Stem Cell Transplant ◽  
Unit Response ◽  
Liposomal Amphotericin B ◽  
High Dose ◽  
Cell Transplant

scholarly journals Sporobolomyces salmonicolor: A case report of a rare cutaneous fungal infection

2019 ◽  
Vol 7 ◽  
pp. 2050313X1984415
Author(s):  
Rahina Damji ◽  
Atreyi Mukherji ◽  
Farheen Mussani
Keyword(s):  
Infectious Disease ◽  
Case Report ◽  
Fungal Infection ◽  
Amphotericin B ◽  
Liposomal Amphotericin ◽  
Multiple Organ ◽  
Liposomal Amphotericin B ◽  
Cutaneous Eruption ◽  
Organ Systems ◽  
Cutaneous Fungal Infection

We report a case of a 47-year-old male diagnosed with a cutaneous Sporobolomyces salmonicolor infection after suffering with an extensive cutaneous eruption for 4 years. Treatment can be difficult and options include voriconazole and liposomal amphotericin B. This infectious disease is extremely rare and can have extensive impact on multiple organ systems, including the skin.

scholarly journals Efficacy of Liposomal Amphotericin B and Posaconazole in Intratracheal Models of Murine Mucormycosis

2013 ◽  
Vol 57 (7) ◽  
pp. 3340-3347 ◽  
Author(s):  
Guanpingsheng Luo ◽  
Teclegiorgis Gebremariam ◽  
Hongkyu Lee ◽  
Samuel W. French ◽  
Nathan P. Wiederhold ◽  
...  
Keyword(s):  
Fungal Infection ◽  
Amphotericin B ◽  
Liposomal Amphotericin ◽  
Intratracheal Instillation ◽  
Cortisone Acetate ◽  
Liposomal Amphotericin B ◽  
Immunocompromised Patients ◽  
Content Type ◽  
Pulmonary Mucormycosis ◽  
Life Threatening

ABSTRACTMucormycosis is a life-threatening fungal infection almost uniformly affecting diabetics in ketoacidosis or other forms of acidosis and/or immunocompromised patients. Inhalation ofMucoralesspores provides the most common natural route of entry into the host. In this study, we developed an intratracheal instillation model of pulmonary mucormycosis that hematogenously disseminates into other organs using diabetic ketoacidotic (DKA) or cyclophosphamide-cortisone acetate-treated mice. Various degrees of lethality were achieved for the DKA or cyclophosphamide-cortisone acetate-treated mice when infected with different clinical isolates ofMucorales. In both DKA and cyclophosphamide-cortisone acetate models, liposomal amphotericin B (LAmB) or posaconazole (POS) treatments were effective in improving survival, reducing lungs and brain fungal burdens, and histologically resolving the infection compared with placebo. These models can be used to study mechanisms of infection, develop immunotherapeutic strategies, and evaluate drug efficacies against life-threateningMucoralesinfections.

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