Colonic Rupture in a Patient on Combination Chemotherapy for Metastasized Carcinoma of the Esophagogastric Junction. Case Report and Review of the Literature

2005 ◽  
Vol 28 (4) ◽  
pp. 204-206 ◽  
Author(s):  
Gianluca Colucci ◽  
Walter Thaler ◽  
Hans Dejaco ◽  
Hansjörg Marsoner ◽  
Alexia Grones
2006 ◽  
Vol 16 (Suppl 1) ◽  
pp. 391-393 ◽  
Author(s):  
G. Ostoros ◽  
A. Pretz ◽  
J. Fillinger ◽  
I. Soltesz ◽  
B. Dome

Fatal lung fibrosis caused by paclitaxel toxicity has not been reported In this report, we describe the case of a 62-year-old woman who received six cycles of paclitaxel and carboplatin as combination chemotherapy for advanced ovarian cancer. Four weeks after the end of the chemotherapy she developed interstitial pneumonitis and irreversible lung fibrosis. Despite treatment with corticosteroids, she had rapid deterioration and died of respiratory failure. Pulmonary fibrosis is a complication of paclitaxel therapy that may occur despite treatments with corticosteroids. While reviewing the literature, we found few less severe pulmonary injuries after intravenous use of paclitaxel, but none of these cases had a fatal outcome. Physicians should keep in mind that taxanes such as paclitaxel have the potential to cause pneumonitis and lung fibrosis.


2011 ◽  
Vol 5 (1) ◽  
Author(s):  
Mounia Amzerin ◽  
Zouhour Fadoukhair ◽  
Rhizlane Belbaraka ◽  
Meryem Iraqui ◽  
Saber Boutayeb ◽  
...  

2018 ◽  
Vol 5 (3) ◽  
Author(s):  
Olga Prokopchuk ◽  
Santiago Moreno-Ordaz ◽  
Norbert Hüser ◽  
Jeannine Bachmann ◽  
Björn Konukiewitz ◽  
...  

2017 ◽  
Vol 5 (1) ◽  
pp. 35-39
Author(s):  
Vanda Salutari ◽  
Patricia Pautier

Ovarian small cell carcinoma is a rare tumor associated with poor prognosis. Although combination chemotherapy remains the cornerstone of treatment due to the rarity of these tumors, there is no evidencebased consensus for a standard treatment, although in the majority of cases platinum-based regimens are used. A case of small cell carcinoma of the ovary, hypercalcemic-type (SCCOHT), in a 22 year-old patient is reported.


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