Prevention of Infectious Complications in Surgical Patients: Potential Role of Probiotics

2005 ◽  
Vol 22 (4) ◽  
pp. 234-244 ◽  
Author(s):  
Marc G.H. Besselink ◽  
Harro M. Timmerman ◽  
L. Paul van Minnen ◽  
Louis M.A. Akkermans ◽  
Hein G. Gooszen
2014 ◽  
Vol 13 (11) ◽  
pp. 1307-1316 ◽  
Author(s):  
Ulla Bonde ◽  
Jan Stener Joergensen ◽  
Ole Mogensen ◽  
Ronald F Lamont

2019 ◽  
Vol 12 (2) ◽  
pp. 87-93
Author(s):  
Ralitsa P. Stavrova-Hristova

Summary Cholesterol is a white, waxy substance that always takes part in building each cell in the human body. The role of cholesterol in the normal functioning of the human body has been known for a long time, however, it is mainly due to its elevated levels and the health risk of it. It is less well known that low serum cholesterol levels are associated with serious health problems. When it comes to intensive care unit (ICU) patients, hypocholesterolemia may indicate infectious complications, impaired hepatic synthesis, significant bodily injury. Surgical patients are judged for operative trauma and perioperative stress, as well as for the resuscitation process.


2019 ◽  
Vol 70 (5) ◽  
pp. 968-972 ◽  
Author(s):  
David P Serota ◽  
Joshua A Barocas ◽  
Sandra A Springer

Abstract Infectious diseases (ID) physicians are increasingly responsible for the management of infectious consequences of substance use disorders (SUD). While we are often consulted for diagnosis and treatment of the infectious disease, it is clear that successful management of these infections requires a holistic approach, including acknowledgement and treatment of the underlying SUD. As we have learned through years of treating human immunodeficiency virus and hepatitis C virus infections, ID physicians have unique expertise in addressing both the infection and the complex biopsychosocial factors that underpin the infection. Many ID physicians have incorporated the management of addiction as part of their scope of practice, and here we seek to give a name and define the role of these ID/addiction dual specialists. We define the potential role of ID/addiction physicians in clinical care, health administration, and research, as well as provide recommendations to bolster the supply and reach of this burgeoning subspecialty.


2019 ◽  
Vol 47 (5) ◽  
pp. 1393-1404 ◽  
Author(s):  
Thomas Brand

Abstract The Popeye domain-containing gene family encodes a novel class of cAMP effector proteins in striated muscle tissue. In this short review, we first introduce the protein family and discuss their structure and function with an emphasis on their role in cyclic AMP signalling. Another focus of this review is the recently discovered role of POPDC genes as striated muscle disease genes, which have been associated with cardiac arrhythmia and muscular dystrophy. The pathological phenotypes observed in patients will be compared with phenotypes present in null and knockin mutations in zebrafish and mouse. A number of protein–protein interaction partners have been discovered and the potential role of POPDC proteins to control the subcellular localization and function of these interacting proteins will be discussed. Finally, we outline several areas, where research is urgently needed.


Author(s):  
Katherine Guérard ◽  
Sébastien Tremblay

In serial memory for spatial information, some studies showed that recall performance suffers when the distance between successive locations increases relatively to the size of the display in which they are presented (the path length effect; e.g., Parmentier et al., 2005) but not when distance is increased by enlarging the size of the display (e.g., Smyth & Scholey, 1994). In the present study, we examined the effect of varying the absolute and relative distance between to-be-remembered items on memory for spatial information. We manipulated path length using small (15″) and large (64″) screens within the same design. In two experiments, we showed that distance was disruptive mainly when it is varied relatively to a fixed reference frame, though increasing the size of the display also had a small deleterious effect on recall. The insertion of a retention interval did not influence these effects, suggesting that rehearsal plays a minor role in mediating the effects of distance on serial spatial memory. We discuss the potential role of perceptual organization in light of the pattern of results.


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