The Role of Cholesterol in Assessing the Condition of the Surgical Patients

2019 ◽  
Vol 12 (2) ◽  
pp. 87-93
Author(s):  
Ralitsa P. Stavrova-Hristova
Keyword(s):  
Human Body ◽  
Infectious Complications ◽  
Surgical Patients ◽  
Operative Trauma ◽  
Bodily Injury ◽  
Cholesterol Levels ◽  
Long Time ◽  
Waxy Substance ◽  
Hepatic Synthesis

Summary Cholesterol is a white, waxy substance that always takes part in building each cell in the human body. The role of cholesterol in the normal functioning of the human body has been known for a long time, however, it is mainly due to its elevated levels and the health risk of it. It is less well known that low serum cholesterol levels are associated with serious health problems. When it comes to intensive care unit (ICU) patients, hypocholesterolemia may indicate infectious complications, impaired hepatic synthesis, significant bodily injury. Surgical patients are judged for operative trauma and perioperative stress, as well as for the resuscitation process.

Prevention of Infectious Complications in Surgical Patients: Potential Role of Probiotics

2005 ◽  
Vol 22 (4) ◽  
pp. 234-244 ◽  
Author(s):  
Marc G.H. Besselink ◽  
Harro M. Timmerman ◽  
L. Paul van Minnen ◽  
Louis M.A. Akkermans ◽  
Hein G. Gooszen
Keyword(s):  
Potential Role ◽  
Infectious Complications ◽  
Surgical Patients

scholarly journals Pengembangan Kursi Kerja Ergonomis di UKM Tenun Ikat Medali Mas

2019 ◽  
Vol 3 (1) ◽  
pp. 26
Author(s):  
Ary Permatadeny Nevita
Keyword(s):  
Body Size ◽  
Production Process ◽  
Human Body ◽  
Sitting Position ◽  
Sitting Posture ◽  
Work Station ◽  
Seat Cushion ◽  
Long Time ◽  
Chair Design

The role of humans as a source of labor in SME weaving is still very dominant in the production process, especially when the production process of converting yarn into fabric with non-machine looms. Sitting position during the process of weaving activities that lasts a long time with 8 hours per day, causes the sitting position to be less comfortable and cause complaints of pain in the back or spine. The purpose of this study is to produce an ergonomic work chair design with an anthropometric approach to improve comfort, reduce fatigue and other health effects caused by sitting positions that are less comfortable than the previous work chair, by focusing the work chair design on human body size. The results of this study are the development of weaving work chairs can be achieved by the addition of the backrest and cushion on the seat cushion of the chair as well as the addition of high-low chair settings according to anthropometry of workers compared to pre-existing weaving work chairs. Anthropometric measurements using the 5th and 95th percentiles obtained the dimensions of the work chair dimensions: 1) The height of the chair from the floor 95 cm, 2) The height of the seat cushion from the floor 52 cm, 3) The width of the seat base 39 cm, 4) The width of the backrest 35 cm, 5) Back length 31 cm, 6) Back height 49 cm. Keyword : ergonomics, anthropometry, work station design, sitting posture, work chair Peranan manusia sebagai sumber tenaga kerja pada UKM tenun ikat masih sangat dominan dalam proses produksinya terutama saat kegiatan proses produksi pengubah benang menjadi kain dengan alat tenun bukan mesin (ATBM). Posisi duduk pada saat proses pelaksaan kegiatan menenun yang secara terus menerus dengan waktu 8 jam per hari, menyebabkan posisi duduk menjadi kurang nyaman dan mengakibatkan   keluhan sakit terhadap punggung ataupun tulang belakang. Tujuan dari penelitian ini adalah menghasilkan rancangan kursi kerja yang ergonomi dengan pendekatan antropometri untuk meningkatkan kenyamanan, mengurangi kelelahan dan dampak-dampak negatif yang disebabkan akibat posisi duduk yang kurang nyaman dari kursi kerja sebelumnya, dengan memfokuskan rancangan kursi kerja pada ukuran tubuh manusia. Hasil dari penelitian ini adalah pengembangan kursi kerja tenun  dapat dicapai dengan penambahan sandaran serta bantalan pada alas tempat duduk pada kursi serta penambahan pada pengaturan tinggi rendah kursi sesuai dengan anthropometri pekerja dibandingkan dengan kursi kerja tenun yang sudah ada sebelumnya. Pengukuran secara anthropometri menggunakan persentil ke-5 dan ke-95 maka diperoleh rancangan dimensi kursi kerja: 1) Tinggi kursi dari lantai 95 cm, 2) Tinggi alas duduk dari lantai 52 cm, 3) Lebar alas kursi 39 cm, 4) Lebar sandaran 35 cm, 5) Panjang sandaran 31 cm, 6) Tinggi sandaran 49 cm.Kata Kunci: ergonomi, anthropometri, perancangan stasiun kerja, sikap duduk, kursi kerja

scholarly journals Human Body Scents: Do they Influence our Behavior?

2013 ◽  
Vol 8 (11) ◽  
pp. 1934578X1300801
Author(s):  
Sophie Mildner ◽  
Gerhard Buchbauer
Keyword(s):  
Human Behavior ◽  
Human Body ◽  
Vomeronasal Organ ◽  
Pheromonal Communication ◽  
Long Time ◽  
Receptor Organ ◽  
Human Pheromones ◽  
Human Sense ◽  
Odorous Substances

Pheromonal communication in the animal world has been of great research interest for a long time. While extraordinary discoveries in this field have been made, the importance of the human sense of smell was of far lower interest. Humans are seen as poor smellers and therefore research about human olfaction remains quite sparse compared with other animals. Nevertheless amazing achievements have been made during the past 15 years. This is a collection of available data on this topic and a controversial discussion on the role of putative human pheromones in our modern way of living. While the focus was definitely put on behavioral changes evoked by putative human pheromones this article also includes other important aspects such as the possible existence of a human vomeronasal organ. If pheromones do have an influence on human behavior there has to be a receptor organ. How are human body scents secreted and turned into odorous substances? And how can con-specifics detect those very odors and transmit them to the brain? Apart from that the most likely candidates for human pheromones are taken on account and their impact on human behavior is shown in various detail.

The Problem of Identifying and Modeling the Relationship between Monetary Factor and Inflation in the Russian Economy

2008 ◽  
pp. 61-76
Author(s):  
A. Porshakov ◽  
A. Ponomarenko
Keyword(s):  
Money Supply ◽  
Money Demand ◽  
Russian Economy ◽  
Long Run ◽  
Complex Approach ◽  
Wide Range ◽  
Long Time ◽  
The Relationship ◽  
Supply Side Factors

The role of monetary factor in generating inflationary processes in Russia has stimulated various debates in social and scientific circles for a relatively long time. The authors show that identification of the specificity of relationship between money and inflation requires a complex approach based on statistical modeling and involving a wide range of indicators relevant for the price changes in the economy. As a result a model of inflation for Russia implying the decomposition of inflation dynamics into demand-side and supply-side factors is suggested. The main conclusion drawn is that during the recent years the volume of inflationary pressures in the Russian economy has been determined by the deviation of money supply from money demand, rather than by money supply alone. At the same time, monetary factor has a long-run spread over time impact on inflation.

Role of Vasavaleha in the management of Covid19

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 259-261
Author(s):  
Aamir Khan ◽  
Rajni K. Gurmule
Keyword(s):  
Immune System ◽  
Human Body ◽  
Respiratory Diseases ◽  
Spreading Rate ◽  
Host Immune System ◽  
Shortness Of Breath ◽  
Antitussive Effect ◽  
Corona Viruses ◽  
Very High

Vasavaleha is one of the best medicine given for respiratory diseases. Corona viruses typically affect the respiratory system, causing symptoms such as coughing, fever and shortness of breath. It also affects host immune system of human body. Spreading rate of this disease is very high. Whole world is seeking for the treatment which can uproots this diseases. There in no vaccine available till date against this pandemic disease. Ayurveda mainly focuses on prevention of diseases alongwith its total cure. Rajyakshma Vyadhi is MadhyamMarga Roga as per Ayurveda. It shows many symptoms such as Kasa, Shwasa etc. By overall view of Covid 19, shows its resemblance with Rajyakshma Vyadhi described in Ayurveda. Vasavaleha is a Kalpa which is described in Rogadhikara of Rajyakshma. It shows Kasahara, Shwashara properties. It consists of Vasa, Pipalli, Madhu and Goghrita. These components shows actions like bronchodilation, antitussive effect and many more other actions. Pipalli shows important Rasayana effect. So in present review, we have tried to focus on role of Vasavaleha in the management of Covid 19. This can be used as preventive as well as adjuvant medication in treating Covid 19. There is need of further clinical research to rule of exact action of Vasavaleha against Covid 19.

ПОЕТИЧНА МОВОТВОРЧІСТЬ ЯК ВІДОБРАЖЕННЯ КОНЦЕПТУАЛЬНОЇ КАРТИНИ СВІТУ

2018 ◽  
pp. 166-174
Author(s):  
М. В. Дзисюк
Keyword(s):  
Semantic Space ◽  
Spiritual Values ◽  
Spatial Features ◽  
Filling Ability ◽  
Material Reality ◽  
Space Saving ◽  
Long Time ◽  
Literary Techniques ◽  
Linguistic Process

Definitions of concept and sphere of the concept are widely used in different aspects of modern linguistics. There is no single understanding of these notions and universal methodology of research has not been invented by linguists yet. This predetermines topicality of the article. The aim of our research is analysis, generalization, and systematization of different approaches to the interpretation of the notion ‘concept’ that exist in modern linguistics. It results in the following tasks: analysis of existing definitions of concept and its division into certain ranges and defining classification features. Modern linguists raise the questions of the conceptual and linguistic image of the world, the role of a human factor in its formation and interaction as in a linguistic process more frequently and it is defined as a fact in today’s linguistic scientific literature. The problem of individual language formation, poetic one in particular gains important meaning in this context. Ukrainian linguists use the notion of ‘concept’ for a long time now although they adhere to different views on its definition. Researches of the question define two major approaches in the analysis of the notion ‘concept’ that is linguistic-cognitive and linguistic-cultural. We can claim that words-concepts are agents between material reality and the ideal world that is synthesized in poetry, carriers of sense since with their help the versatility of the real world correlates with eternal spiritual values. Therefore, main features of the notion ‘concept’ in which objectively-cognitive and subjectively-creative features are combines are as follow sensual authenticity, time-spatial features, mediation between material and spiritual, semantic filling, ability to polysemy. A word with a generally symbolic meaning that is implemented in a language process through literary techniques typical for poet’s idiotype is the main core of the concept. The concept in poetic language formation by modern Uman poets is semantically integral, fulfilled, able to penetrate into other concepts and absorb semantically narrower images saving unity and semantic independence, varying numerous interpretations that project it in a certain semantic space, saving potential of real reflection.

„Arvīd, uz kurieni Tu aizgāji?”: Arvīda Griguļa personības loma Rakstnieku savienības vēsturē

2020 ◽  
pp. 74-84
Author(s):  
Madara Eversone
Keyword(s):  
20Th Century ◽  
Communist Party ◽  
Central Committee ◽  
State Archive ◽  
National Archives ◽  
Literary Heritage ◽  
Literary Process ◽  
Long Time ◽  
The Impact

The article aims to highlight the role of Arvīds Grigulis’ (1906–1989) personality in the Latvian Soviet literary process in the context of the Latvian Soviet Writers’ Union, attempting to discover the contradictions and significance of Arvīds Grigulis’ personality. Arvīds Grigulis was a long-time member of the Writers’ Union, a member of the Soviet nomenklatura, and an authority of the soviet literary process. His evaluations of pre-soviet literary heritage and writings of his contemporaries were often harsh and ruthless, and also influenced the development of the further literary process. The article is based on the documents of the Central Committee of the Latvian Communist Party, the Latvian Soviet Writers’ Union and the Communist Party local organization of the Latvian Soviet Writers’ Union that are available at the Latvian State Archive of the National Archives of Latvia, as well as memories of Grigulis’ contemporaries. It is concluded that the personality of the writer Arvīds Grigulis, although unfolding less in the context of the Writers’ Union, is essential for the exploration of the soviet literary process and events behind the scenes. The article mainly describes events and episodes taking place until 1965, when Arvīds Grigulis’ influence in the Writers’ Union was more remarkable. Individual and further studies should analyse changes and the impact of his decisions in the cultural process of the 70s and 80s of the 20th century.

Acid-Sensing Ion Channels

2020 ◽  
Author(s):  
Stefan Gründer
Keyword(s):  
Nervous System ◽  
Ion Channels ◽  
Excitatory Synapses ◽  
Detailed Characterization ◽  
High Affinity ◽  
Acid Sensing Ion Channels ◽  
Long Time ◽  
Pathological Pain

Acid-sensing ion channels (ASICs) are proton-gated Na+ channels. Being almost ubiquitously present in neurons of the vertebrate nervous system, their precise function remained obscure for a long time. Various animal toxins that bind to ASICs with high affinity and specificity have been tremendously helpful in uncovering the role of ASICs. We now know that they contribute to synaptic transmission at excitatory synapses as well as to sensing metabolic acidosis and nociception. Moreover, detailed characterization of mouse models uncovered an unanticipated role of ASICs in disorders of the nervous system like stroke, multiple sclerosis, and pathological pain. This review provides an overview on the expression, structure, and pharmacology of ASICs plus a summary of what is known and what is still unknown about their physiological functions and their roles in diseases.

scholarly journals Physiological and Psychological Effects of Watching Videos of Different Durations Showing Urban Bamboo Forests with Varied Structures

2020 ◽  
Vol 17 (10) ◽  
pp. 3434
Author(s):  
Yuqian Wang ◽  
Mingyan Jiang ◽  
Yinshu Huang ◽  
Zhiyi Sheng ◽  
Xiao Huang ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Skin Conductance ◽  
Human Body ◽  
Stable State ◽  
Mean Value ◽  
Psychological Effects ◽  
Physiological Indicators ◽  
Psychological Indicators ◽  
Before And After ◽  
Long Time

This study illustrated the physiological and psychological effects of watching videos of different durations showing bamboo forests with varied structures. Physiological indicators, including EEG (electroencephalogram), blood pressure, skin conductance, and pulse, were monitored in 180 Chinese university students (mean age: 20.72 ± 2.56 years) while they were watching bamboo videos. Before and after watching the videos, their psychological indicators, including positive and negative moods, were measured using the Profile of Mood States questionnaire. After watching the bamboo videos of different durations, all of the physiological indicators responded to the stimulation after only 1 min. The indicators showed different trends at 1, 3 and 5 min. EEG decreased and then was maintained at a stable level after 1 min, and the high β, low β, and α waves had no significant differences between 1, 3 and 5 min. Blood pressure dropped to a stable state after 3 min, and the decline was significantly different greater after 3 min than after 1 min. Skin conductance increased for 1 to 5 min, and it did not stabilize after a long time (5 min). Pulse decreased after 1 min but increased after 5 min. After watching the videos with bamboo of varying structures, the physiological and psychological indicators showed significantly different changes. Skin conductance significantly increased (mean value: 6.78%), and the amount of sweat was more effectively reduced, thereby reducing tension, when the students viewed videos of sympodial bamboo forests compared with monopodial bamboo forests. Bamboo forests with a higher canopy density (0.83–0.85) could significantly decrease α waves (mean value: 1.50 Hz), relaxing the human body. High β and low β waves showed greater decreases, with tension reduced more effectively, when bamboo forests with a low tilt ratio (< 1.5%) were viewed. Bamboo forests with neat undergrowth could have more beneficial physiological and psychological effects on the human body.

scholarly journals Abnormal brain cholesterol homeostasis in Alzheimer’s disease—a targeted metabolomic and transcriptomic study

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Vijay R. Varma ◽  
H. Büşra Lüleci ◽  
Anup M. Oommen ◽  
Sudhir Varma ◽  
Chad T. Blackshear ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Brain Tissue ◽  
Cholesterol Metabolism ◽  
Cholesterol Biosynthesis ◽  
Cholesterol Homeostasis ◽  
Transcriptomic Data ◽  
Brain Cholesterol ◽  
Cholesterol Levels

AbstractThe role of brain cholesterol metabolism in Alzheimer’s disease (AD) remains unclear. Peripheral and brain cholesterol levels are largely independent due to the impermeability of the blood brain barrier (BBB), highlighting the importance of studying the role of brain cholesterol homeostasis in AD. We first tested whether metabolite markers of brain cholesterol biosynthesis and catabolism were altered in AD and associated with AD pathology using linear mixed-effects models in two brain autopsy samples from the Baltimore Longitudinal Study of Aging (BLSA) and the Religious Orders Study (ROS). We next tested whether genetic regulators of brain cholesterol biosynthesis and catabolism were altered in AD using the ANOVA test in publicly available brain tissue transcriptomic datasets. Finally, using regional brain transcriptomic data, we performed genome-scale metabolic network modeling to assess alterations in cholesterol biosynthesis and catabolism reactions in AD. We show that AD is associated with pervasive abnormalities in cholesterol biosynthesis and catabolism. Using transcriptomic data from Parkinson’s disease (PD) brain tissue samples, we found that gene expression alterations identified in AD were not observed in PD, suggesting that these changes may be specific to AD. Our results suggest that reduced de novo cholesterol biosynthesis may occur in response to impaired enzymatic cholesterol catabolism and efflux to maintain brain cholesterol levels in AD. This is accompanied by the accumulation of nonenzymatically generated cytotoxic oxysterols. Our results set the stage for experimental studies to address whether abnormalities in cholesterol metabolism are plausible therapeutic targets in AD.

Sign in / Sign up

Export Citation Format

Share Document