Tissue Reaction to Polypropylene Mesh: A Study of Oedema, Blood Flow, and Inflammation in the Abdominal Wall

1991 ◽  
Vol 23 (3-4) ◽  
pp. 240-249 ◽  
Author(s):  
S. Dabrowiecki ◽  
K. Svanes ◽  
J. Lekven ◽  
K. Grong
Keyword(s):  
Blood Flow ◽  
Abdominal Wall ◽  
Polypropylene Mesh ◽  
Tissue Reaction

scholarly journals COMPARATIVE ULTRASTRUCTURAL CHARACTERISTICS OF THE EFFECT OF “LIGHTWEIGHT” AND “HEAVYWEIGHT” POLYPROPYLENE MESHES ON THE PRO-CESSES OF ANTERIOR ABDOMINAL WALL TISSUE REGENERATION WHEN PERFORMING RETROMUSCULAR ALLOGENEOPLASTY

2018 ◽  
Vol 17 (2) ◽  
pp. 76-83
Author(s):  
V. I. Pyatnochk ◽  
I. Ya. Dzyubanovsʹkyy ◽  
K. S. Volkov
Keyword(s):  
Abdominal Wall ◽  
Polypropylene Mesh ◽  
Anterior Abdominal Wall ◽  
Tissue Reaction ◽  
Tissue Response ◽  
Ultrastructural Changes ◽  
Lightweight Mesh ◽  
Aseptic Inflammation ◽  
Ultrastructural Studies ◽  
Tissue Reactions

The ultrastructural changes of the tissues of musculo-aponeurotic layer of anterior abdominal wall after implantation of the “lightweight” and “heavyweight” polypropylene meshes into the retrometallic space were studied in the experiment. Significant differences of the tissue reactions at different periods of the experiment on the implanted material were evidenced. The presence of a moderately pronounced inflammatory tissue reaction was noticed on the 14th day of the study in the area of the implantation of the “lightweight” polypropylene mesh compared to the “heavyweight” one: the inflammatory response included acute manifestations of aseptic inflammation with a significant tissue response. On the 28th day of the experiment, in cases of implantation of the “lightweight” mesh, the stabilization of tissue reaction to the implant with reduction of inflammatory changes was observed, as evidenced by a significantly smaller number of leukocyte infiltration sites, a significant improvement in vascularization and development of collagen fibres around the mesh material with fibroblasts, which was not observed in the area of implantation of the “heavyweight” polypropylene mesh. The conducted morphological and ultrastructural studies have prioritized the use of “lightweight” meshes when choosing material to perform allohernioplasty.

Pneumoperitoneum impairs blood flow and augments tumor growth in the abdominal wall

2004 ◽  
Vol 18 (2) ◽  
pp. 293-296 ◽  
Author(s):  
O. Lundberg ◽  
A. Kristoffersson
Keyword(s):  
Blood Flow ◽  
Tumor Growth ◽  
Abdominal Wall

Blood flow and tissue reaction at skin wound closures

1988 ◽  
Vol 12 (5) ◽  
pp. 635-640 ◽  
Author(s):  
Yukio Nagamachi
Keyword(s):  
Blood Flow ◽  
Skin Wound ◽  
Tissue Reaction

scholarly journals Evaluation of peritoneal adhesions formation and tissue response to polypropylene - poli (2-hydroxyethyl methacrylate)-(polyHEMA) implant on rats' abdominal wall

2010 ◽  
Vol 25 (4) ◽  
pp. 337-341 ◽  
Author(s):  
Neusa Margarida Paulo ◽  
Sonia Maria Malmonge ◽  
Liliana Borges de Menezes ◽  
Flávia Gontijo de Lima ◽  
Aline de Moraes Faria ◽  
...  
Keyword(s):  
Abdominal Wall ◽  
Polypropylene Mesh ◽  
Histopathological Examination ◽  
Adhesion Formation ◽  
Foreign Body Response ◽  
Tissue Response ◽  
Female Rats ◽  
Hydroxyethyl Methacrylate ◽  
Peritoneal Adhesions ◽  
Body Response

PURPOSE: To verify if the composit poli (2-hydroxyethyl methacrylate)-PolyHEMA/polypropylene mesh implanted in the female rat's abdominal wall could be suitable for the prevention of peritoneal adhesions, and for the evaluation of the tecidual response produced by this biomaterial. METHODS: Polypropylene meshes (Group PP, n=20) and polypropylene meshes coated with a layer of poli (2-hydroxyethyl methacrylate)-PolyHEMA (Group PH, n=20) were implanted on the abdominal wall of Wistar female rats. Ten animals from each group were submitted to euthanasia at 15 and 30 days of the postoperative period. RESULTS: The animals from the group PP presented visceral adhesions on the mesh surface, which was not observed in the ones from group PH. At the histopathological examination foreign body response was observed in both groups, whilst there was a greater intensity of inflammatory response in group PH on both moments. CONCLUSION: The poli (2-hydroxyethyl methacrylate) polyHEMA hydrogel associated to polypropylene mesh reduces visceral adhesion formation in rats, although it may be associated to greater inflammatory reaction.

scholarly journals ESTIMATION OF THE EFFECT OF PLATELET RICH PLASMA PRODUCTS IN THE INTEGRATION OF POLYPROPYLENE MESH IMPLANT IN BIOLOGICAL TISSUES. EXPERIMENTAL MODEL IN RATS

2018 ◽  
Vol 5 ◽  
pp. 11-19
Author(s):  
Dmitro Atanasov
Keyword(s):  
Stem Cells ◽  
Adipose Tissue ◽  
Polypropylene Mesh ◽  
Morphological Changes ◽  
Platelet Rich Plasma ◽  
Biological Tissues ◽  
Tissue Reaction ◽  
Plasma Cytokines ◽  
Mesh Implant ◽  
Positive Effect

The aim of the research is to determine morphological changes in the area of implantation of the polypropylene mesh implant and to determine the effect on the integration of the prosthesis of locally introduced adipose tissue and platelet rich plasma. Materials and methods. The experiment was performed on 36 sexually mature males of the Wistar line rats. The experiment simulated, studied and quantified local morphological responses and changes in developing in biological tissues that are in contact with implanted highly porous lightweight (80 g/m2) mesh implant in isolation and also in conditions of local administration of fatty graft and platelet rich plasma. Results: Assuming introduction of adipose tissue and platelet rich plasma in the zone of integration of mesh alloprosthesis under the influence of introduced regenerative cytokines as well as stromal stem cells activated by them there is an earlier activation of regenerative processes, enhanced angiogenesis which determines the optimal nature of the integration of the prosthesis with the formation of thin collagen fibers in more early terms minimizing excess peri-prosthetic fibrosis. Isolated introduction into the implantation zone of fatty suspension determines similar changes that have a slightly less pronounced character. These changes are quantitatively studied and the results obtained are statistically significant. Conclusions: Applying a fatty graft together with platelet rich plasma in the area of implantation of the lung polypropylene prosthesis, there was an accelerated tissue reaction from the integration of the prosthesis. Mesenchymal stem cells of adipose tissue that is a target for plasma cytokines enriched with thrombocytes have a more pronounced effect in stimulating reparative processes provided that they are simultaneously administered with PRP compared with isolated administration without PRP. The use of platelet rich plasma and adipose tissue design has a significant positive effect on local angiogenesis. Under conditions of improved angiogenesis and other stimulating factors in the conditions of introduction of adipose tissue and PRP, the integration of the prosthesis occurs with significantly lower peri-prosthetic fibrosis.

Liver

2020 ◽  
pp. 155-166
Author(s):  
Jad M. Abdelsattar ◽  
Moustafa M. El Khatib ◽  
T. K. Pandian ◽  
Samuel J. Allen ◽  
David R. Farley
Keyword(s):  
Blood Flow ◽  
Chronic Hepatitis ◽  
Liver Disease ◽  
Hepatitis C ◽  
Liver Failure ◽  
Abdominal Wall ◽  
Alcoholic Liver Disease ◽  
Nonalcoholic Steatohepatitis ◽  
Falciform Ligament ◽  
Ascites Tumors

The liver arises from the foregut-midgut junction. It is contained in the Glisson capsule, and the falciform ligament attaches the liver to the anterior abdominal wall. Hepatocytes perform approximately 500 functions. Chronic hepatitis C, alcoholic liver disease, and nonalcoholic steatohepatitis may cause cirrhosis and give rise to liver failure and potentially HCC. MRI, CT, and US are helpful for determining the extent of cirrhosis and detecting ascites, tumors, and blood flow. Fifty percent to 80% of the liver can be resected if the remainder functions well. Liver resections may bleed, leak bile, or lead to infection.

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