Calcitonin Gene-Related Peptide in Morphologically Well-Defíned Type II Neurons of the Enteric Nervous System in the Porcine Small Intestine

1987 ◽  
Vol 129 (4) ◽  
pp. 325-328 ◽  
Author(s):  
Dietrich W. Scheuermann ◽  
Werner Stach ◽  
Marie H.A. De Groodt-Lasseel ◽  
Jean-Pierre Timmermans
2000 ◽  
Vol 285 (1) ◽  
pp. 33-36 ◽  
Author(s):  
Yoshiaki Doi ◽  
Hong Peng ◽  
Hideaki Kudo ◽  
Kunshige Hamasaki ◽  
Sunao Fujimoto

1995 ◽  
Vol 73 (7) ◽  
pp. 945-956 ◽  
Author(s):  
Gerhard Skofitseh ◽  
Wolfgang Gubisch ◽  
Sunil J. Wimalawansa ◽  
David M. Jacobowitz

Using the indirect immunofluorescence method with a polyclonal antiserum raised in rabbits and directed against amylin (AMY), we have investigated the distribution of AMY-like immunoreactivity (-ir) throughout the central nervous system of the rat. The widespread distribution of AMY-ir was much more abundant than that previously reported for calcitonin gene related peptide (CGRP) immunoreactivity. In most brain areas there was no overlap between AMY- and CGRP-ir cell body groupings, with the exception of the motor nuclei of the hindbrain and spinal cord, which were found to contain large numbers of AMY- and CGRP-immunoreactive cell bodies. Areas with a moderate to dense appearance of AMY-ir were the rhinencephalon, the nucleus of the diagonal band, the magnocellular, dorso- and ventro-medial and mammillary nuclei of the hypothalamus, the habenula, the compact part of the substantia nigra, the ruber and pontine nuclei, and the inferior olive and the cerebellar nuclei. The widespread immunohistochemical distribution of AMY-ir in the rat brain is in partial agreement with the distribution of AMY-binding sites.Key words: calcitonin gene related peptide, amylin, central nervous system, immunohistochemistry, rat.


Sign in / Sign up

Export Citation Format

Share Document