Tight Junctions of Human Uterine Epithelial Cells Change during the Menstrual Cycle: A Morphometric Study

1992 ◽  
Vol 144 (1) ◽  
pp. 36-38 ◽  
Author(s):  
C.R. Murphy ◽  
P.A.W. Rogers ◽  
M.J. Hosie ◽  
J. Leeton ◽  
L. Beaton
2005 ◽  
Vol 267 (1) ◽  
pp. 103-108 ◽  
Author(s):  
Amanda M. Preston ◽  
Laura A. Lindsay ◽  
Christopher R. Murphy

1992 ◽  
Vol 7 (6) ◽  
pp. 883-885 ◽  
Author(s):  
P. A. W. Rogers ◽  
C. R. Murphy ◽  
J. Leeton ◽  
M. J. Hosie ◽  
L. Beaton

1985 ◽  
Vol 78 (1) ◽  
pp. 163-172
Author(s):  
C.R. Murphy ◽  
B. Martin

Freeze-fracture cytochemistry with digitonin has been used to examine the cholesterol content of the plasma membrane of uterine epithelial cells during the early stages of pregnancy in the rat. Lesions caused by digitonin complexing with cholesterol were seen on both lateral and apical portions of the membrane but tight junctions and desmosomes were lesion-free. Compared with day 1 of pregnancy, lesions on the apical plasma membrane were much more extensive and some were of different morphology on day 6 - the day of blastocyst implantation. We consider mechanisms of lesion formation and interpret the results to indicate a higher content and perhaps a different organization of cholesterol in the apical plasma membrane on day 6 of pregnancy. We also suggest how this increase may occur.


Author(s):  
A. C. Enders

The alteration in membrane relationships seen at implantation include 1) interaction between cytotrophoblast cells to form syncytial trophoblast and addition to the syncytium by subsequent fusion of cytotrophoblast cells, 2) formation of a wide variety of functional complex relationships by trophoblast with uterine epithelial cells in the process of invasion of the endometrium, and 3) in the case of the rabbit, fusion of some uterine epithelial cells with the trophoblast.Formation of syncytium is apparently a membrane fusion phenomenon in which rapid confluence of cytoplasm often results in isolation of residual membrane within masses of syncytial trophoblast. Often the last areas of membrane to disappear are those including a desmosome where the cell membranes are apparently held apart from fusion.


2012 ◽  
Vol 5 (6) ◽  
pp. 870-880 ◽  
Author(s):  
Y. Yin ◽  
C. Lin ◽  
G. M. Veith ◽  
H. Chen ◽  
M. Dhandha ◽  
...  

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