A Benign Sickle-Cell Disease in a Saudi Subject with β°-Thalassemia and Glucose-6-Phosphate Dehydrogenase Deficiency

1989 ◽  
Vol 39 (2) ◽  
pp. 118-120
Author(s):  
A.I. Alayash ◽  
J. Bonaventura ◽  
A. Al-Quorain
Keyword(s):  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Dehydrogenase Deficiency ◽  
Cell Disease ◽  
Glucose 6 Phosphate Dehydrogenase

scholarly journals Epidemiology of hereditary anemias in Saudi Arabia

2021 ◽  
Author(s):  
Shada Murshed Alharbi ◽  
Jawad Hussain Alshaiti ◽  
Jamila Mofareh Ghazwani ◽  
Afia Mofareh Ghazwani ◽  
Nawaf Mohammed Abushelwah ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Dehydrogenase Deficiency ◽  
Epidemiological Studies ◽  
Cell Disease ◽  
The Past ◽  
Prevalence Trends ◽  
High Prevalence ◽  
Glucose 6 Phosphate Dehydrogenase

The prevalence rates of hereditary anemias in Saudi Arabia are remarkably high when compared to other countries. For instance, estimates show that the prevalence of thalassemia constitutes one of the highest rates globally. Furthermore, it has been demonstrated that epidemiology significantly differs between the different regions across the Kingdom. Therefore, many epidemiological investigations were conducted. In this context, it has been demonstrated that the prevalence of thalassemia ranges from 0.4% to 5.9% in the Northern and Eastern regions, respectively. In the present literature review, we have discussed the different findings of epidemiological studies that studied the epidemiology of hereditary anemias in Saudi Arabia. We mainly discussed the epidemiology of glucose-6-phosphate dehydrogenase deficiency (G6PD), sickle cell disease, and thalassemia. Recent evidence indicates that the trends of β-thalassemia are significantly decreasing over the past years. On the other hand, it has been demonstrated that the prevalence trends of sickle cell disease is constant over the past years. G6PD is also highly prevalent in Saudi Arabia. However, recent evidence is lacking in the literature and needs to be updated by future investigations. Consanguineous marriage has been reported to be an important risk factor for the high prevalence of β-thalassemia and sickle cell disease across the Kingdom.

Neonatal Screening for Sickle Cell Disease, Glucose-6-Phosphate Dehydrogenase Deficiency and α-Thalassemia in Qatif and Al Hasa

1998 ◽  
Vol 18 (4) ◽  
pp. 289-292 ◽  
Author(s):  
Zaki Nasserullah ◽  
Abdulaziz Al Jame ◽  
Hussain Abu Srair ◽  
Ghazi Al Qatari ◽  
Saad Al Naim ◽  
...  
Keyword(s):  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Neonatal Screening ◽  
Dehydrogenase Deficiency ◽  
Cell Disease ◽  
Glucose 6 Phosphate Dehydrogenase

The clinical impact of glucose-6-phosphate dehydrogenase deficiency in patients with sickle cell disease

2018 ◽  
Vol 25 (6) ◽  
pp. 494-499 ◽  
Author(s):  
Matthew S. Karafin ◽  
Xiaoyun Fu ◽  
Angelo D’Alessandro ◽  
Tiffany Thomas ◽  
Eldad A. Hod ◽  
...  
Keyword(s):  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Dehydrogenase Deficiency ◽  
Clinical Impact ◽  
Cell Disease ◽  
Glucose 6 Phosphate Dehydrogenase

The effect of the coinheritance of Glucose-6-phosphate dehydrogenase deficiency on the severity of sickle cell disease

2019 ◽  
Vol 26 (2) ◽  
pp. 118
Author(s):  
TaiwoRachel Kotila ◽  
FolukeAtinuke Fasola ◽  
FlorenceOlamide Fowodu ◽  
WuraolaAdebola Shokunbi
Keyword(s):  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Dehydrogenase Deficiency ◽  
Cell Disease ◽  
Glucose 6 Phosphate Dehydrogenase

Glucose-6-Phosphate Dehydrogenase Deficiency and Homozygous Sickle Cell Disease in Congo

1998 ◽  
Vol 48 (4) ◽  
pp. 192-197 ◽  
Author(s):  
Jean Claude Bouanga ◽  
René Mouélé ◽  
Claude Préhu ◽  
Henri Wajcman ◽  
Josué Feingold ◽  
...  
Keyword(s):  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Dehydrogenase Deficiency ◽  
Cell Disease ◽  
Glucose 6 Phosphate Dehydrogenase ◽  
Homozygous Sickle Cell Disease

scholarly journals Premarital counselling: an experience from Bahrain

1997 ◽  
Vol 3 (3) ◽  
pp. 415-419
Author(s):  
Shaikha Salim Al Arrayed ◽  
Nada Hafadh ◽  
Samera Al Serafi
Keyword(s):  
At Risk ◽  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Dehydrogenase Deficiency ◽  
Sickle Cell Trait ◽  
Cell Disease ◽  
Beta Thalassaemia ◽  
Thalassaemia Trait ◽  
Analyse Data ◽  
Glucose 6 Phosphate Dehydrogenase

The present study was conducted to analyse data of the first 500 clients who voluntarily attended premarital counselling during 1993-1994. It was found that 74.1% of clients were not related to their partner, 23.2% were first cousins and 1.5% were second cousins;the rest were distant relatives. Sickle-cell disease was found in 1.6% of clients, sickle-cell trait in 13.0%, beta-thalassaemia trait in 2.0% and glucose-6-phosphate dehydrogenase deficiency in 26.0%. Of the couples attending counselling, 8.1% were found to be at risk of having affected offspring. The consanguinity rate among the couples at risk was 15.4%

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