Possible Protective Effect of Chronic Renal Failure against Sepsis and Endotoxin-lnduced Organ Failure and Mortality in Acute Renal Failure

1. γ-Glutamyl l-dopa, a renal pro-drug for dopamine, was administered to rats before and after injection of glycerol, and to a control group which received water in place of glycerol. A third group of rats was given glycerol but no γ-glutamyl l-dopa. 2. The plasma creatinine in rats given γ-glutamyl l-dopa and glycerol was significantly lower than in rats receiving glycerol alone. 3. The fall in urine creatinine excretion, and polyuria, after glycerol was reduced by γ-glutamyl l-dopa and the natriuresis abolished. 4. γ-Glutamyl l-dopa given alone caused a 4000-fold increase in urine dopamine excretion, associated with a natriuresis. 5. The administration of γ-glutamyl l-dopa reduces the severity of renal failure produced by glycerol.

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Continuous renal replacement therapy is associated with less chronic renal failure than intermittent haemodialysis after acute renal failure

Yearbook of Critical Care Medicine ◽

10.1016/s0734-3299(08)70597-5 ◽

2008 ◽

Vol 2008 ◽

pp. 241-243

Author(s):

C. Bekes

Keyword(s):

Renal Failure ◽

Acute Renal Failure ◽

Chronic Renal Failure ◽

Renal Replacement Therapy ◽

Continuous Renal Replacement Therapy ◽

Replacement Therapy ◽

Intermittent Haemodialysis

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Acute renal failure after transarterial chemoembolization progressing to chronic renal failure in hepatocellular carcinoma

Nephrology Dialysis Transplantation ◽

10.1093/ndt/15.5.741 ◽

2000 ◽

Vol 15 (5) ◽

pp. 741-742 ◽

Cited By ~ 3

Author(s):

Moon‐Jae Kim ◽

Seoung Woo Lee ◽

Gyeong A Kim ◽

Joon Ho Song

Keyword(s):

Hepatocellular Carcinoma ◽

Renal Failure ◽

Acute Renal Failure ◽

Chronic Renal Failure ◽

Transarterial Chemoembolization

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Protective effect of heme oxygenase induction in ischemic acute renal failure

Critical Care Medicine ◽

10.1097/00003246-200003000-00033 ◽

2000 ◽

Vol 28 (3) ◽

pp. 809-817 ◽

Cited By ~ 129

Author(s):

Hiroko Shimizu ◽

Toru Takahashi ◽

Tsutomu Suzuki ◽

Akira Yamasaki ◽

Tadao Fujiwara ◽

...

Keyword(s):

Renal Failure ◽

Acute Renal Failure ◽

Protective Effect ◽

Heme Oxygenase ◽

Ischemic Acute Renal Failure

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Uroangiographic Contrast Media-Induced Nephropathy: Correlations between Their Physicochemical Properties and Renal Damage

Urologia Journal ◽

10.1177/039156030507200405 ◽

2005 ◽

Vol 72 (4) ◽

pp. 446-456

Author(s):

C. Alberti ◽

M. Piovano ◽

A. Tizzani

Keyword(s):

Diabetes Mellitus ◽

Renal Failure ◽

Acute Renal Failure ◽

Chronic Renal Failure ◽

Contrast Media ◽

Renal Damage ◽

Contrast Material ◽

Vasoactive Mediators ◽

Adequate Hydration ◽

Hospital Acquired

Contrast media-induced nephropathy (CN) is an important cause of hospital-acquired acute renal failure. Patients with both diabetes mellitus and renal impairment are at high risk. CN pathophysiology involves activation of the tubulo-glomerular feedback and vasoactive mediators such as renin-angiotensin 2, endothelin, adenosine, ADH, etc. The risk of CN can be minimized by the use of non-ionic, low or isoosmolar, contrast material, adequate hydration and prophylactic pharmacological measures. In patients with chronic renal failure who are undergoing arteriography (e.g. coronary angiography and angioplasty), periprocedural hemofiltration appears effective in preventing further renal damage due to contrast agents.

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