Existence of c-kit Receptor-Positive, Tryptase-Negative, IgE-Negative Cells in Human Allergic Nasal Mucosa: A Candidate for Mast Cell Progenitor

1997 ◽  
Vol 112 (1) ◽  
pp. 36-43 ◽  
Author(s):  
Shinichi Kawabori ◽  
Naoki Kanai ◽  
Takuro Tosho ◽  
Toshihide Adachi
Keyword(s):  
Mast Cell ◽  
Nasal Mucosa ◽  
Mast Cell Progenitor

Inflammatory biomarker, neopterin, enlarges splenic mast-cell-progenitor pool: Prominent impairment of responses in age-related stromal cell-impairment mouse SCI/SAM

2006 ◽  
Vol 6 (12) ◽  
pp. 1847-1858 ◽  
Author(s):  
Toshitaka Fukumoto ◽  
Isao Tsuboi ◽  
Tomonori Harada ◽  
Masaki Hiramoto ◽  
Akihiro Minami ◽  
...  
Keyword(s):  
Mast Cell ◽  
Stromal Cell ◽  
Inflammatory Biomarker ◽  
Age Related ◽  
Mast Cell Progenitor

scholarly journals Lymphocyte and mast cell counts are increased in the nasal mucosa in symptomatic natural colds

2003 ◽  
Vol 131 (1) ◽  
pp. 138-142 ◽  
Author(s):  
O.-P. ALHO ◽  
T. J. KARTTUNEN ◽  
R. KARTTUNEN ◽  
H. TUOKKO ◽  
M. KOSKELA ◽  
...  
Keyword(s):  
Mast Cell ◽  
Nasal Mucosa ◽  
Cell Counts

Mast cell stabilizers

1992 ◽  
Vol 107 (6_part_2) ◽  
pp. 841-844 ◽  
Author(s):  
Hueston C. King
Keyword(s):  
Allergic Rhinitis ◽  
Mast Cell ◽  
Cell Membrane ◽  
Nasal Mucosa ◽  
Nasal Polyps ◽  
Nasal Congestion ◽  
Correct Diagnosis ◽  
Vasomotor Rhinitis ◽  
Ige Mediated ◽  
Exercise Induced

The precise mode of action of the well-studied cromolyn sodium and the newer nedocromil sodium has not been completely elucidated. Because the drugs do not pass the cell membrane and enter the cell, they are virtually not metabolized, do not exert a systemic action, and therefore are associated with only minimal systemic toxicity. To be effective either drug must be applied topically and directly to the nasal mucosa. Proper contact with the nasal mucosa is essential for efficacy; in patients with nasal congestion and secretions, vasoconstrictors or saline lavages are indicated before cromolyn or nedocromil use. Both products are highly effective in patients who have IgE-mediated allergic rhinitis but must be administered prophylactically before exposure to an allergen to prevent development of the allergic event. Neither drug is effective in vasomotor rhinitis, exercise-induced rhinitis, or in the management of nasal polyps. Correct diagnosis is essential before therapy.

scholarly journals Antigen-Induced Increases in Pulmonary Mast Cell Progenitor Numbers Depend on IL-9 and CD1d-Restricted NKT Cells

2009 ◽  
Vol 183 (8) ◽  
pp. 5251-5260 ◽  
Author(s):  
Tatiana G. Jones ◽  
Jenny Hallgren ◽  
Alison Humbles ◽  
Timothy Burwell ◽  
Fred D. Finkelman ◽  
...  
Keyword(s):  
Mast Cell ◽  
Nkt Cells ◽  
Mast Cell Progenitor

scholarly journals KIT signaling is dispensable for human mast cell progenitor development

Blood ◽  
2017 ◽  
Vol 130 (16) ◽  
pp. 1785-1794 ◽  
Author(s):  
Joakim S. Dahlin ◽  
Maria Ekoff ◽  
Jennine Grootens ◽  
Liza Löf ◽  
Rose-Marie Amini ◽  
...  
Keyword(s):  
Mast Cell ◽  
Human Mast Cell ◽  
Key Points ◽  
Mast Cell Progenitor

Key Points SCF and KIT signaling are dispensable for the survival, proliferation, and maturation of human mast cell progenitors.

A self-renewing, bipotential erythroid/mast cell progenitor in continuous cultures of normal murine bone marrow

1985 ◽  
Vol 125 (1) ◽  
pp. 10-18 ◽  
Author(s):  
Fran�oise Wendling ◽  
Mona Shreeve ◽  
David McLeod ◽  
Arthur Axelrad
Keyword(s):  
Bone Marrow ◽  
Mast Cell ◽  
Continuous Cultures ◽  
Murine Bone Marrow ◽  
Mast Cell Progenitor
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