Esophageal Ulceration due to Oral Medications

Objectives: To minimise the dose of Anti-platelet drugs and to treat the acute case of DVT through Ayurvedic oral medications. Methods: The present diagnosed case of DVT approached to OPD of KLE BMK Ayurveda Hospital with a complaints of swelling and pain in the calf muscle of the left lower limb associated with reddish brown discoloration in the foot and occasionally nasal and gum bleeding was treated consequently for 5 months with Punarnavadi Mandoor and Shiva Gutika orally. Results: There is significant decrease in the symptoms of DVT and also major changes seen in Venous Colour Doppler study of the left lower limb. Conclusion: Acute DVT is caused by a blood clot in a deep vein and can be life threatening as it may leads to serious complication like pulmonary embolism which can be cured through Ayurvedic oral medications.

Download Full-text

Ayurvedic understanding of Central Pontine Myelinolysis - A Case Report

Journal of Ayurveda and Integrated Medical Sciences (JAIMS) ◽

10.21760/jaims.v3i3.12900 ◽

2018 ◽

Vol 3 (3) ◽

Author(s):

Anoop AS ◽

Lakshmiprasad L. Jadhav ◽

Sruthy Nair ◽

Rohan Mohandas

Keyword(s):

Serum Sodium Level ◽

Central Pontine Myelinolysis ◽

Chronic Alcoholism ◽

Serum Electrolyte ◽

Oral Medications ◽

Shoulder Joints ◽

Pontine Myelinolysis ◽

Chief Complaints ◽

Hyponatremic Encephalopathy ◽

Central Pontine

A 56 year old male patient was admitted to S.D.M Ayurveda Hospital, Hassan, Karnataka with the confirmed diagnosis of Central Pontine Myelinolysis (CPM) on 11/12/17. The chief complaints were weakness of both hands and legs, stiffness in both hands and legs, pain in both shoulder joints, slurred speech, difficulty in walking with gait changes. H/O chronic alcoholism. MRI brain showed pontine and basal ganglia diffusion restriction - Acute Pontine Myelinolysis. The serum electrolyte showed serum sodium level as 128 mmol/litre. This disease can be understood as Samana Avruta Vyana in hyponatremic encephalopathy stage and the stage of myelinolysis can be understood as Sarvanga Vata with Kapha Avruta Udana and Vyana. After clinical evaluation, Avarana Chikitsa was started followed by Kevala Vatika Chikitsa and significant improvement was seen. Significant result was observed in subjective and objective parameters after the treatment. The patient was discharged with oral medications for 1 month.

Download Full-text

Feedback of patient survey on medication improves the management of polypharmacy: a pilot trial

BMC Family Practice ◽

10.1186/s12875-021-01396-x ◽

2021 ◽

Vol 22 (1) ◽

Author(s):

Yuta Hirose ◽

Kiyoshi Shikino ◽

Yoshiyuki Ohira ◽

Sumihide Matsuoka ◽

Chihiro Mikami ◽

...

Keyword(s):

Health Professionals ◽

Questionnaire Survey ◽

Pilot Trial ◽

Patient Survey ◽

Contributing Factors ◽

Chi Square ◽

Oral Medications ◽

Medical Institutions ◽

Chi Square Test ◽

Survey Results

Abstract Background Patient awareness surveys on polypharmacy have been reported previously, but no previous study has examined the effects of sending feedback to health professionals on reducing medication use. Our study aimed to conduct a patient survey to examine factors contributing to polypharmacy, feedback the results to health professionals, and analyze the resulting changes in the number of polypharmacy patients and prescribed medications. Methods After conducting a questionnaire survey of patients in Study 1, we provided its results to the healthcare professionals, and then surveyed the number of polypharmacy patients and oral medications using a before-after comparative study design in Study 2. In Study 1, we examined polypharmacy and its contributing factors by performing logistic regression analysis. In Study 2, we performed a t-test and a chi-square test. Results In the questionnaire survey, significant differences were found in the following 3 items: age (odds ratio (OR) = 3.14; 95% confidence interval (CI) = 2.01–4.91), number of medical institutions (OR = 2.34; 95%CI = 1.50–3.64), and patients’ difficulty with asking their doctors to deprescribe their medications (OR = 2.21; 95%CI = 1.25–3.90). After the feedback, the number of polypharmacy patients decreased from 175 to 159 individuals and the mean number of prescribed medications per patient decreased from 8.2 to 7.7 (p < 0.001, respectively). Conclusions Providing feedback to health professionals on polypharmacy survey results may lead to a decrease in the number of polypharmacy patients. Factors contributing to polypharmacy included age (75 years or older), the number of medical institutions (2 or more institutions), and patients’ difficulty with asking their physicians to deprescribe their medications. Feedback to health professionals reduced the percentage of polypharmacy patients and the number of prescribed medications. Trial registration UMIN. Registered 21 June 2020 - Retrospectively registered, https://www.umin.ac.jp/ctr/index-j.htm

Download Full-text

Time to Switch Herpes Simplex Virus Oral Medications From Prescription to Over-the-Counter

Infectious Diseases in Clinical Practice ◽

10.1097/ipc.0000000000000662 ◽

2018 ◽

Vol 26 (6) ◽

pp. e93-e94

Author(s):

Alyssa M. Aldridge ◽

Francine Touzard Romo ◽

Timothy P. Flanigan

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Over The Counter ◽

Oral Medications ◽

Simplex Virus

Download Full-text

Antiepileptic Drug Management in Hospitalized Epilepsy Patients With Nil Per Os Diets: A Retrospective Review

The Neurohospitalist ◽

10.1177/1941874418802513 ◽

2018 ◽

Vol 9 (2) ◽

pp. 65-70

Author(s):

Anna M. Bank ◽

Jong Woo Lee ◽

Alexa N. Ehlert ◽

Aaron L. Berkowitz

Keyword(s):

Antiepileptic Drug ◽

Medical Center ◽

Academic Medical Center ◽

Management Strategies ◽

Hospital Setting ◽

Drug Selection ◽

Drug Management ◽

Oral Medications ◽

Academic Medical ◽

Patients With Epilepsy

Background and Purpose: Antiepileptic drug (AED) management in patients with epilepsy who cannot take their usual oral medications is a common neurologic dilemma in the hospital setting. Strategies to maintain seizure control in patients with nil per os (NPO, nothing by mouth) diet orders include continuation of oral AEDs despite NPO nutrition orders, administration of intravenous AED(s), or temporary administration of benzodiazepines. The frequency with which these strategies are used and their effectiveness in preventing in-hospital seizures is unknown. Methods: We conducted a retrospective cohort study to determine AED management strategies and seizure frequency in hospitalized epilepsy patients with NPO diet status admitted to an academic medical center between 2001 and 2016. Clinical documentation was reviewed. Antiepileptic drug selection (medication and route of administration) and presence or absence of seizures were recorded. Results: We identified 199 admissions during which epilepsy patients had NPO diet orders. Antiepileptic drug management strategies included continuation of oral medications (50.3% of admissions), intravenous AED monotherapy (22.1%), intravenous AED polytherapy (12.6%), benzodiazepines (1.0%), holding AEDs (4.5%), or a combination (9.5%). Seizures occurred during 14 admissions. Treatment with AED polytherapy prior to admission and changing the patient’s AED regimen during admission were associated with increased odds of seizures during admission ( P = .0028; P = .0114). Conclusions: These results suggest that patients’ home oral AED regimens should be continued when possible in order to minimize the frequency of seizures during hospitalizations.

Download Full-text

Updated List of Light-Sensitive Oral Medications

Hospital Pharmacy ◽

10.1177/0018578719844699 ◽

2019 ◽

Vol 55 (6) ◽

pp. 349-365

Author(s):

Scott Perkins ◽

Adam Evans ◽

Allison King

Keyword(s):

Dosage Form ◽

Drug Information ◽

Dosage Forms ◽

Drug Products ◽

Solid Dosage ◽

Oral Medications ◽

Information Center ◽

Oral Liquid ◽

Liquid Products ◽

Professional Resources

The Campbell University Drug Information Center supports health professionals by providing responses to drug-related inquiries. An inquiry was received by the Drug Information Center for a comprehensive list of oral solutions which should be protected from light. In investigating this request for information, a list of light-sensitive oral prescription drug products published in Hospital Pharmacy in 2009 was identified. This discovery highlighted the need for both an updated list and one which distinguished oral solid products and oral liquid products. The purpose of this project was to update the previously published list and to distinguish between oral solid and liquid dosage forms. The process of updating this list entailed several professional resources. A list of all oral products was obtained and then sorted to clearly identify which products were available in oral solid dosage form only, oral liquid dosage form only, and both dosage forms. Once delineated, the product labels for each medication were scoured for language indicating the product is light sensitive.

Download Full-text