Exogenous Nerve Growth Factor Promotes the Repair of Cardiac Sympathetic Heterogeneity and Electrophysiological Instability in Diabetic Rats

Cardiology ◽  
2013 ◽  
Vol 127 (3) ◽  
pp. 155-163 ◽  
Author(s):  
Mei Xue ◽  
Yong-Li Xuan ◽  
Ye Wang ◽  
He-Sheng Hu ◽  
Xiao-Lu Li ◽  
...  
2017 ◽  
Vol 32 (3) ◽  
pp. 903-912 ◽  
Author(s):  
Yuxing Zhao ◽  
Zhaoxing Shen ◽  
Dongling Zhang ◽  
Huiqiong Luo ◽  
Jinliang Chen ◽  
...  

2020 ◽  
Vol 35 (8) ◽  
pp. 1431-1432
Author(s):  
Yuxing Zhao ◽  
Zhaoxing Shen ◽  
Dongling Zhang ◽  
Huiqiong Luo ◽  
Jinliang Chen ◽  
...  

2002 ◽  
Vol 30 (5) ◽  
pp. 512-519 ◽  
Author(s):  
H Kanbayashi ◽  
H Itoh ◽  
T Kashiwaya ◽  
K Atoh ◽  
I Makino

This study investigated the time-course of the nociceptive neuropeptide substance P and nerve growth factor (NGF), which facilitates substance P production, in lumbar and cervical dorsal root ganglia (DRG) of streptozotocin-induced diabetic rats. Levels of substance P and NGF were measured by radioimmunoassay and sandwich enzyme-linked immunosorbent assay, respectively, 2 months, 4 months and 8 months after induction of diabetes, and compared with age-matched non-diabetic control rats. At 2 months and 4 months, substance P and NGF levels were lower in the lumbar DRG of the diabetic rats than in controls. At 8 months, substance P and NGF were lower in both the lumbar and cervical DRG of the diabetic rats than in controls. These data demonstrate that a decrease in substance P levels in primary sensory neurons with NGF depletion occurs in an axonal length-dependent manner in diabetic rats, and that this decrease may be correlated with the duration of diabetes.


2015 ◽  
Vol 1624 ◽  
pp. 455-468 ◽  
Author(s):  
Marzia Soligo ◽  
Virginia Protto ◽  
Fulvio Florenzano ◽  
Luisa Bracci-Laudiero ◽  
Fabrizio De Benedetti ◽  
...  

2013 ◽  
Vol 14 (7) ◽  
pp. 720-730 ◽  
Author(s):  
Mohammed Shaqura ◽  
Baled I. Khalefa ◽  
Mehdi Shakibaei ◽  
Jens Winkler ◽  
Mahmoud Al-Khrasani ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document