scholarly journals Physiological Correlates of Neurobehavioral Disinhibition that Relate to Drug Use and Risky Sexual Behavior in Adolescents with Prenatal Substance Exposure

2014 ◽  
Vol 36 (3-4) ◽  
pp. 306-315 ◽  
Author(s):  
Elisabeth Conradt ◽  
Linda L. Lagasse ◽  
Seetha Shankaran ◽  
Henrietta Bada ◽  
Charles R. Bauer ◽  
...  
2011 ◽  
Vol 23 (3) ◽  
pp. 777-788 ◽  
Author(s):  
Philip A. Fisher ◽  
Barry M. Lester ◽  
David S. DeGarmo ◽  
Linda L. Lagasse ◽  
Hai Lin ◽  
...  

AbstractThe negative effects of prenatal substance exposure on neurobiological and psychological development and of early adversity are clear, but little is known about their combined effects. In this study, multilevel analyses of the effects of prenatal substance exposure and early adversity on the emergence of neurobehavioral disinhibition in adolescence were conducted. Neurobehavioral disinhibition has previously been observed to occur frequently in multiproblem youth from high-risk backgrounds. In the present study, neurobehavioral disinhibition was assessed via behavioral dysregulation and poor executive function composite measures. Data were drawn from a prospective longitudinal investigation of prenatal substance exposure that included 1,073 participants followed from birth through adolescence. The results from latent growth modeling analyses showed mean stability but significant individual differences in behavioral dysregulation and mean decline with individual differences in executive function difficulties. Prior behavioral dysregulation predicted increased executive function difficulties. Prenatal drug use predicted the emergence and growth in neurobehavioral disinhibition across adolescence (directly for behavioral dysregulation and indirectly for executive function difficulties via early adversity and behavioral dysregulation). Prenatal drug use and early adversity exhibited unique effects on growth in behavioral dysregulation; early adversity uniquely predicted executive function difficulties. These results are discussed in terms of implications for theory development, social policy, and prevention science.


2020 ◽  
Vol 216 ◽  
pp. 108260 ◽  
Author(s):  
Tyrel J. Starks ◽  
S. Scott Jones ◽  
Daniel Sauermilch ◽  
Matthew Benedict ◽  
Trinae Adebayo ◽  
...  

2014 ◽  
Vol 49 (11) ◽  
pp. 1457-1464 ◽  
Author(s):  
Liesl A. Nydegger ◽  
Susan L. Ames ◽  
Alan W. Stacy ◽  
Jerry L. Grenard

2009 ◽  
Vol 19 (5) ◽  
pp. 605-620 ◽  
Author(s):  
Ainhoa Rodriguez Garcia de Cortazar ◽  
Andres Cabrera Leon ◽  
Mariano Hernan Garcia ◽  
Juan Manuel Jimenez Nunez

1994 ◽  
Vol 8 (1) ◽  
pp. 3-7 ◽  
Author(s):  
John Schafer ◽  
Laura Blanchard ◽  
William Fals-Stewart

2020 ◽  
Vol 8 (E) ◽  
pp. 256-261
Author(s):  
Emmanuel Amoo ◽  
Olujide A. Adekeye ◽  
Florence Omumu ◽  
Olubunmi O. Akinpelu ◽  
Mofoluwake P. Ajayi ◽  
...  

BACKGROUND: Sexual risk behavior and drug abuse among adolescents and youths remained perpetual topical issues of focus in most developmental programs related to developing countries, especially in Nigeria, where the school-going adolescents constitute more than half of the youths. The high level of teenage pregnancy and sexual violence such as abuses and other harmful trajectories including STIs and HIV is increasingly reported than the pre-2000s. AIM: This study focuses on underscoring the variation in risky sexual behavior among school-going users and non-users of drugs. It also analyzed the predisposing factors of drug use among school-going adolescents in Nigeria. METHODS: In combination with problem behavior theory, the research draws data (n = 11,799) from the 2012 National HIV and AIDS and Reproductive Health Survey (NARHS Plus II) collated by the Federal Ministry of Health in Nigeria with support from the Department for International Development and United States Agency for International Development, to underscore the self-reported sexual risk behavior among students who are users and non-users of drugs. RESULTS: The result revealed that 32.5% (male) and 33.4% (female) use drugs. More than half of the respondents reported that they have engaged in sexual intercourse, 27.3% (male) and 31.8% (female) have had ≥2 lifetime sexual partners. There is higher odds ratio (OR) of risky sexual behavior among students that have ever used drugs or taken alcohol (OR = 2.2, 95% CI [1.8–2.8]) for male and (OR = 2.1, 95% CI [0.83–2.03]) for female. CONCLUSION: The study concludes that continued exposure of school-going youths to drugs or alcohol may pose serious challenge of risky sexual behavior and also severe threat to initiatives on zero new HIV infections or zero new AIDS death in Nigeria. The authors recommend that campaign to discourage drug or alcohol use should be intensified and introduced to all schools.


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