Research on Reproduction at the New England Regional Primate Research Center1

2015 ◽  
pp. 198-202 ◽  
Author(s):  
B. F. Trum
Keyword(s):  
New England ◽  
Regional Primate Research ◽  
Primate Research

scholarly journals Evolution of Two Types of Rhesus Lymphocryptovirus Similar to Type 1 and Type 2 Epstein-Barr Virus

1999 ◽  
Vol 73 (11) ◽  
pp. 9206-9212 ◽  
Author(s):  
Young-Gyu Cho ◽  
Alexey V. Gordadze ◽  
Paul D. Ling ◽  
Fred Wang
Keyword(s):  
New England ◽  
Epstein Barr Virus ◽  
B Cell Lymphoma ◽  
Regional Primate Research ◽  
Primate Research ◽  
Barr Virus ◽  
Immunodeficiency Virus ◽  
Epstein Barr

ABSTRACT Rhesus monkeys and other nonhuman Old World primates are naturally infected with lymphocryptoviruses (LCV) that are closely related to Epstein-Barr virus (EBV). A rhesus LCV isolate (208-95) was derived from a B-cell lymphoma in a simian immunodeficiency virus-infected rhesus macaque. The EBNA-2 homologues from 208-95 and a previous rhesus LCV isolate (LCL8664) were polymorphic on immunoblotting, so the EBNA-2 genes from these two rhesus LCV were cloned, sequenced, and compared. The EBNA-2 genes have 40% nucleotide and 41% amino acid identities, and the differences are similar to those between the type 1 and type 2 EBV EBNA-2. Sequence from a portion of the LMP1 gene which is extremely divergent among different LCV was virtually identical between the 208-95 and LCL8664 strains, confirming a common rhesus LCV background. Thus, the EBNA-2 polymorphism defines the presence of two different rhesus LCV types, and both rhesus LCV types were found to be prevalent in the rhesus monkey population at the New England Regional Primate Research Center. The existence of two rhesus LCV types suggests that the selective pressure for the evolution of two LCV types is shared by human and nonhuman primate hosts.

scholarly journals Simian Neonatology: I. Gestational Maturity and Extrauterine Viability

1972 ◽  
Vol 9 (5) ◽  
pp. 301-309 ◽  
Author(s):  
R. A. Price ◽  
Miriam R. Anver ◽  
F. G. Garcia
Keyword(s):  
Birth Weight ◽  
New England ◽  
Neonatal Period ◽  
Perinatal Period ◽  
Saimiri Sciureus ◽  
Regional Primate Research ◽  
Primate Research ◽  
Saguinus Oedipus ◽  
Death Rates ◽  
Neonatal Deaths

In a 21-month period, 225 simians were born at the New England Regional Primate Research Center. Of these, 141 (63%) survived the neonatal period, and 84 (37%) were either born dead or died during the first 30 days of life. Sixty-two of the 84 neonatal deaths occurred during the perinatal period (0–7 days of life). In four macaque species studied, groups of infants that were high and low survival risks were established by examining weight-specific death rates. Criteria for establishing immaturity by birth weight were suggested in Saguinus oedipus and Saimiri sciureus.

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