Interactions between Glutamate and Dopamine in the Ventral Striatum: Evidence for a Dual Glutamatergic Function with Respect to Motor Control

Author(s):  
Anders Svensson ◽  
Maria L. Carlsson ◽  
Arvid Carlsson
2016 ◽  
Vol 18 (1) ◽  
pp. 7-21 ◽  

Corticostriatal connections play a central role in developing appropriate goal-directed behaviors, including the motivation and cognition to develop appropriate actions to obtain a specific outcome. The cortex projects to the striatum topographically. Thus, different regions of the striatum have been associated with these different functions: the ventral striatum with reward; the caudate nucleus with cognition; and the putamen with motor control. However, corticostriatal connections are more complex, and interactions between functional territories are extensive. These interactions occur in specific regions in which convergence of terminal fields from different functional cortical regions are found. This article provides an overview of the connections of the cortex to the striatum and their role in integrating information across reward, cognitive, and motor functions. Emphasis is placed on the interface between functional domains within the striatum.


2010 ◽  
Vol 20 (2) ◽  
pp. 29-36
Author(s):  
Erin M. Wilson ◽  
Ignatius S. B. Nip

Abstract Although certain speech development milestones are readily observable, the developmental course of speech motor control is largely unknown. However, recent advances in facial motion tracking systems have been used to investigate articulator movements in children and the findings from these studies are being used to further our understanding of the physiologic basis of typical and disordered speech development. Physiologic work has revealed that the emergence of speech is highly dependent on the lack of flexibility in the early oromotor system. It also has been determined that the progression of speech motor development is non-linear, a finding that has motivated researchers to investigate how variables such as oromotor control, cognition, and linguistic factors affect speech development in the form of catalysts and constraints. Physiologic data are also being used to determine if non-speech oromotor behaviors play a role in the development of speech. This improved understanding of the physiology underlying speech, as well as the factors influencing its progression, helps inform our understanding of speech motor control in children with disordered speech and provide a framework for theory-driven therapeutic approaches to treatment.


2014 ◽  
Author(s):  
Pin-Hao Andy Chen ◽  
Paul J. Whalen ◽  
Jonathan B. Freeman ◽  
James M. Taylor ◽  
Todd F. Heatherton
Keyword(s):  

2009 ◽  
Author(s):  
Robert M. Kohl ◽  
Raymond W. McCoy ◽  
Jacob K. Mutch

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