Optical Coherence Tomography Angiography of Iris Nevus: A Case Report

Iris nevus is common: 6% of patients with suspected iris melanoma have lesions other than melanoma, and 36% of them are nevi. Iris nevus turns into melanoma in approximately 8% of cases at a mean of 15 years. This case report provides the first description of an iris tumor examined with iris optical coherence tomography angiography (OCTA) compared to iris fluorescein angiography (IFA). A 60-year-old man with a diagnosis of iris nevus in the left eye was referred to our department for IFA and iris OCTA. The iris vasculature in IFA was visible only in the early phases, but not clearly. OCTA, however, gave visualization of the vascular network and very precisely defined the vessels of the whole lesion, except for the pupillary portion, which was masked by superficial pigment accumulations. IFA and iris OCTA can add information about the vascular architecture compared to slit-lamp biomicroscopy, ultrasound biomicroscopy, and anterior-segment OCT. However, IFA is time-consuming and invasive and can – very occasionally – cause serious adverse reactions. In contrast, OCTA defines the texture of the iris vasculature better. In conclusion, OCTA is a new method, easy to execute, needing no dye injection, and provides useful information on the vascular network of iris lesions. It could therefore be helpful in the diagnosis and follow-up of these lesions.

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Case Report: A Case of Perifoveal Exudative Vascular Anomalous Complex With a Good Prognosis

Frontiers in Medicine ◽

10.3389/fmed.2021.757313 ◽

2021 ◽

Vol 8 ◽

Author(s):

Min Fu ◽

Pan Hu ◽

Gang Zhang ◽

Ludonghan Huang ◽

Huan Xu ◽

...

Keyword(s):

Optical Coherence Tomography ◽

Case Report ◽

Optical Coherence Tomography Angiography ◽

Case Reports ◽

Good Prognosis ◽

Optical Coherence ◽

Irreversible Damage ◽

Micropulse Laser ◽

History Of

Significance: Perifoveal exudative vascular anomalous complex (PEVAC) is a unique clinical lesion. It manifests as isolated lesions and is easily misdiagnosed. Thus far, few PEVAC case reports have been published. PEVAC is typically inconsistent with other reported macular lesions.Purpose: To report our 24-month follow-up experience on the treatment of PEVAC with a micropulse laser (MPL).Case Report: A 56-year-old Chinese woman with no history of other diseases complained of decreased vision in her left eye that had persisted for more than 1 year. Comprehensive ophthalmic examinations were performed, including a vision test, slit lamp fundus exam, optical coherence tomography (OCT), optical coherence tomography angiography (OCT-A), fluorescein fundus angiography (FFA) and indocyanine green angiography (ICGA). Intravitreal injection of ranibizumab was ineffective, and bleeding, exudation and visual acuity were not improved. After two rounds of micropulse laser (MPL) treatment, the patient was followed up, and the prognosis was good.Conclusion: PEVAC is very rare, and early diagnosis is important, as the lesions readily cause irreversible damage. Our results indicate that an MPL can be used as an alternative treatment for PEVAC patients.

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Diagnosis and Follow-Up of Nonexudative Choroidal Neovascularization With Multiple Optical Coherence Tomography Angiography Devices: A Case Report

Ophthalmic Surgery Lasers and Imaging Retina ◽

10.3928/23258160-20160808-13 ◽

2016 ◽

Vol 47 (8) ◽

pp. 778-781 ◽

Cited By ~ 5

Author(s):

Mark Lane ◽

Daniela Ferrara ◽

Ricardo Noguera Louzada ◽

James G. Fujimoto ◽

Johanna M. Seddon

Keyword(s):

Optical Coherence Tomography ◽

Case Report ◽

Choroidal Neovascularization ◽

Optical Coherence Tomography Angiography ◽

Optical Coherence

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Optical Coherence Tomography Angiography Evolution of Choroidal Neovascular Membrane in Choroidal Rupture Managed by Intravitreal Bevacizumab

Case Reports in Ophthalmological Medicine ◽

10.1155/2019/5241573 ◽

2019 ◽

Vol 2019 ◽

pp. 1-4 ◽

Cited By ~ 1

Author(s):

Massimo Lorusso ◽

Luisa Micelli Ferrari ◽

Eleni Nikolopoulou ◽

Tommaso Micelli Ferrari

Keyword(s):

Optical Coherence Tomography ◽

Choroidal Neovascularization ◽

Optical Coherence Tomography Angiography ◽

Anterior Segment ◽

Intravitreal Bevacizumab ◽

Optical Coherence ◽

Vascular Structure ◽

Choroidal Neovascular Membrane ◽

Choroidal Rupture

Purpose. To describe a case of a 25-year-old man with choroidal neovascularization (CNV) secondary to traumatic choroidal rupture treated with intravitreal bevacizumab and to evaluate the vascular structure of the area near the traumatic choroidal rupture. Methods. The patient underwent complete ophthalmologic evaluation, including best-corrected visual acuity (BCVA), intraocular pressure, anterior segment and funds examination, and optical coherence tomography angiography (OCTA) at baseline and on each follow-up visit. Fluorescein angiography (FA) was performed at baseline. Intravitreal bevacizumab was administered at the time of choroidal neovascular membrane diagnosis. Results. At baseline, ophthalmoscopic examination of the left eye revealed four subretinal macular hemorrhages and two choroidal ruptures located temporally to the fovea. On OCT angiograms, the choroidal rupture appeared as a hypointense break in choriocapillaris plexus. At 4-week follow-up, the OCTA disclosed a well circumscribed lesion characterized by numerous and fine anastomotic vessels. Patient received intravitreal injection of bevacizumab. At 6-week post injection, OCTA documented regression of the neovascular complex. Conclusion. Choroidal neovascularization is a common complication associated with traumatic choroidal rupture and OCTA may represent a complementary diagnostic technique to evaluate the vascular structure of the area near the traumatic choroidal rupture.

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Pediatric Free-floating Anterior Chamber Cyst of the Iris Pigment Epithelium

American Journal of Ophthalmic Clinical Trials ◽

10.25259/ajoct-5-2018 ◽

2018 ◽

Vol 1 ◽

pp. 3

Author(s):

Joshua S Agranat ◽

Yoshihiro Yonekawa

Keyword(s):

Optical Coherence Tomography ◽

Anterior Chamber ◽

Incidental Finding ◽

Pigment Epithelium ◽

Anterior Segment ◽

Ultrasound Biomicroscopy ◽

Optical Coherence ◽

Visual Axis ◽

Associated Malignancy ◽

Anatomic Locations

Iris pigment epithelial (IPE) cysts are a subset of iris cysts that arise from the IPE. They are spontaneously erupting epithelial-lined cavities that are found in various anatomic locations of the iris, including the iris pupillary margin, midzone, periphery, and free floating in the vitreous or anterior chamber. We report the case of an asymptomatic 13-year-old boy with an incidental finding of a dislodged anterior chamber cyst diagnosed on routine examination. Modern multimodal image analysis of the cyst including anterior segment optical coherence tomography and ultrasound biomicroscopy (UBM) was utilized to characterize the microstructural anatomy of the lesion. The patient was managed conservatively without complications. Cysts of the IPE typically do not affect vision or ocular health and can be monitored and observed after ascertaining no associated malignancy. Initial diagnostic investigation can include UBM and anterior segment optical coherence tomography. Intervention should be reserved only for cases where the cyst growth leads to obstruction of the visual axis and/or other secondary complications.

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The Use of Anterior-Segment Optical-Coherence Tomography for the Assessment of the Iridocorneal Angle and Its Alterations: Update and Current Evidence

Journal of Clinical Medicine ◽

10.3390/jcm10020231 ◽

2021 ◽

Vol 10 (2) ◽

pp. 231

Author(s):

Giacinto Triolo ◽

Piero Barboni ◽

Giacomo Savini ◽

Francesco De Gaetano ◽

Gaspare Monaco ◽

...

Keyword(s):

Optical Coherence Tomography ◽

Intraocular Pressure ◽

Clinical Relevance ◽

Anterior Segment ◽

Angle Closure ◽

Current Evidence ◽

Optical Coherence ◽

Iridocorneal Angle ◽

Wide Range

The introduction of anterior-segment optical-coherence tomography (AS-OCT) has led to improved assessments of the anatomy of the iridocorneal-angle and diagnoses of several mechanisms of angle closure which often result in raised intraocular pressure (IOP). Continuous advancements in AS-OCT technology and software, along with an extensive research in the field, have resulted in a wide range of possible parameters that may be used to diagnose and follow up on patients with this spectrum of diseases. However, the clinical relevance of such variables needs to be explored thoroughly. The aim of the present review is to summarize the current evidence supporting the use of AS-OCT for the diagnosis and follow-up of several iridocorneal-angle and anterior-chamber alterations, focusing on the advantages and downsides of this technology.

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Comparison of the retinal vascular network and structure in patients with optic neuritis associated with myelin oligodendrocyte glycoprotein or aquaporin-4 antibodies: an optical coherence tomography angiography study

Journal of Neurology ◽

10.1007/s00415-021-10609-3 ◽

2021 ◽

Author(s):

Jian Yu ◽

Yongheng Huang ◽

Lei Zhou ◽

Jingzi ZhangBao ◽

Yuan Zong ◽

...

Keyword(s):

Optical Coherence Tomography ◽

Optic Neuritis ◽

Optical Coherence Tomography Angiography ◽

Myelin Oligodendrocyte Glycoprotein ◽

Vascular Network ◽

Aquaporin 4 ◽

Optical Coherence

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Anterior segment optical coherence tomography findings of iris granulomas in Hansen's disease: a case report

Journal of Ophthalmic Inflammation and Infection ◽

10.1186/1869-5760-3-36 ◽

2013 ◽

Vol 3 (1) ◽

pp. 36 ◽

Cited By ~ 4

Author(s):

Padmamalini Mahendradas ◽

Kavitha Avadhani ◽

Sarika Ramachandran ◽

Sahana Srinivas ◽

Madhavi Naik ◽

...

Keyword(s):

Optical Coherence Tomography ◽

Case Report ◽

Anterior Segment ◽

Optical Coherence ◽

Hansen's Disease ◽

Hansen’S Disease

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Spontaneous attachment of complex Descemet’s membrane detachment following multiple failed interventions

BMJ Case Reports ◽

10.1136/bcr-2021-243960 ◽

2021 ◽

Vol 14 (8) ◽

pp. e243960

Author(s):

Shikha Gupta ◽

Karthikeyan Mahalingam ◽

Tushar Agarwal

Keyword(s):

Optical Coherence Tomography ◽

Anterior Segment ◽

Corneal Transplant ◽

Optical Coherence ◽

Initial Attempt ◽

Ocular Tissues ◽

Surgical Interventions ◽

Complicated Cataract ◽

First Time

We describe a case with complex Descemet membrane detachment (DMD) which persisted despite initial two failed surgical attempts to appose the ocular tissues. However, over time, tissue alignment was obtained spontaneously. A 60-year-old woman, operated trabeculectomy, had a total DMD intraoperatively during a complicated cataract surgery. Initial attempt to DM repositioning with intracameral air injection failed. Anterior Segment Optical Coherence Tomography (ASOCT) showed detachment of both DM and pre-Descemet’s layer (PDL). After consultation with a corneal surgeon, patient was again attempted for Intra-operative Optical Coherence Tomography (iOCT)-guided settlement of DMD with intracameral air which again failed. So, the patient was registered for lamellar corneal transplant, but at 3 months follow-up, DM had spontaneously attached, confirmed on ASOCT. This case shows for the first time that even complex DMDs involving PDL, can spontaneously appose despite failed surgical interventions.

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