scholarly journals Gastrointestinal Stromal Tumour with Synchronous Bone Metastases: A Case Report and Literature Review

2017 ◽  
Vol 10 (1) ◽  
pp. 66-76 ◽  
Author(s):  
Philippe Rochigneux ◽  
Lénaig Mescam-Mancini ◽  
Delphine Perrot ◽  
Erwan Bories ◽  
Laurence Moureau-Zabotto ◽  
...  

Gastrointestinal stromal tumours (GISTs) are mesenchymal tumours of the digestive tract, derived from Cajal interstitial cells. Bone metastases are very rare, and there is no consensus regarding their treatment. Here, we present the unusual case of a 66-year-old man with a gastric GIST with synchronous bone and liver metastases, fully documented at the pathological and molecular levels with a KIT exon 11 mutation. After 9 months of imatinib, the scanner showed a 33% partial response of target lesions. We also review the literature and describe the characteristics, treatment, and outcome of all cases previously reported.

2020 ◽  
pp. 014556132090573
Author(s):  
Edgar del Toro ◽  
Adwight Risbud ◽  
Nima Khosravani ◽  
Gennadiy Vengerovich ◽  
Alfredo Archilla

Sphenoid wing meningiomas are tumors that typically present with vision deterioration and neurological changes due to their proximity to the sella, cavernous sinus, and other vital structures. Some unusual symptoms have also been described in the literature, such as cognitive dysfunction, parkinsonism, and intracerebral hemorrhage. In this report, we detail another unusual case of sphenoid wing meningioma in a 63-year-old female who presented with left sudden sensorineural hearing loss. A brief review of the literature is also included.


2016 ◽  
Vol 17 (1) ◽  
pp. 56-59 ◽  
Author(s):  
Abdulmaged M. Musaad ◽  
Nassir Ahaboob Arabi ◽  
Tarig Hussein ◽  
Alsaggad Eltayeb ◽  
Mutaz Salah ◽  
...  

2006 ◽  
Vol 65 (4) ◽  
pp. 402-408 ◽  
Author(s):  
Chow H. Patrick Chan ◽  
Gavin C.A. Fabinyi ◽  
Renate M. Kalnins

Author(s):  
Pieter Ekermans ◽  
Rene de Gama ◽  
Celeste Kock ◽  
Ebrahim Hoosien ◽  
Tomas Slavik ◽  
...  

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