scholarly journals Choreoathetosis Is a Possible Adverse Event of a Commonly Used Antibiotic

2017 ◽  
Vol 9 (1) ◽  
pp. 81-85 ◽  
Author(s):  
Pornchai Sathirapanya
Keyword(s):  
Adverse Event ◽  
Cerebral Cortex ◽  
Literature Review ◽  
End Stage Renal Disease ◽  
Complete Resolution ◽  
Dosage Adjustment ◽  
Systemic Infection ◽  
Pharmacological Interaction ◽  
Stage Renal Disease ◽  
End Stage

Background: Choreoathetosis (CAS) is attributed to a few neuropsychiatric drugs; however, it is scarcely reported with commonly used antibiotics. Aims: To present a case of ceftriaxone (CTX)-induced CAS and to perform a literature review. Setting: A medical teaching hospital. Case History: An 83-year-old female with end stage renal disease was prescribed CTX 2 g/day intravenously and doxycycline (DXC) 200 mg/day orally for the treatment of acute community-acquired systemic infection. CAS developed 3 days after the administration of both drugs. Withdrawal of CTX and DXC yielded complete resolution of the CAS on the following day. Neither neurological adverse events related to DXC use nor pharmacological interaction between DXC and CTX was reported. Therefore, the CAS development was attributed to CTX. Conclusion: CTX as well as other ß-lactam antibiotics induce glutamate excess in the striatum and cerebral cortex, resulting in neurological hyperexcitability disorders. Dosage adjustment of these antibiotics in relation to the patients’ renal clearance is warranted.

Formal literature review of quality-of-life instruments used in end-stage renal disease

2000 ◽  
Vol 36 (2) ◽  
pp. 327-336 ◽  
Author(s):  
Kathleen A. Cagney ◽  
Albert W. Wu ◽  
Nancy E. Fink ◽  
Mollie W. Jenckes ◽  
Klemens B. Meyer ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Literature Review ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Stage Renal Disease ◽  
End Stage ◽  
Quality Of Life Instruments

scholarly journals Literature Review : Efektivitas Terapi Non Farmakologi Terhadap Penurunan Tekanan Darah Pada Pasien End Stage Renal Disease Yang Menjalani Hemodialisis

2021 ◽  
Vol 1 (1) ◽  
pp. 1
Author(s):  
Nurul Pradita ◽  
Kiki Hardiansyah Safitri
Keyword(s):  
Blood Pressure ◽  
Literature Review ◽  
Renal Disease ◽  
Study Design ◽  
End Stage Renal Disease ◽  
Pharmacological Therapy ◽  
Online Database ◽  
Stage Renal Disease ◽  
End Stage ◽  
E Mail

Literature Review : Efektivitas Terapi Non Farmakologi Terhadap Penurunan Tekanan Darah Pada Pasien End Stage Renal Disease Yang Menjalani Hemodialisis Nurul Pradita1, Kiki Hardiansyah Safitri2 1 Mahasiswa Program Studi NERS, ITKES Wiyata Husada, Jl.Kadrie Oening No 77 Samarinda, Kalimantan Timur e-mail : [email protected] 2Dosen, ITKES Wiyata Husada, Jl.Kadrie Oening No 77 Samarinda, Kalimantan Timur e-mail : [email protected]   ABSTRAK   Latar Belakang: End Stage renal disease (ESRD) bisa disebabkan oleh tekanan darah yang tidak terkontrol  (hipertensi) atau  penyakit ginjal dapat menyebabkan hipertensi. Terapi non farmakologi dapat membantu pasien mengatasi tekanan darah dengan efek samping yang minimal. Tujuan: Mengidentifikasi studi literatur efektifitas terapi non farmakologi terhadap penurunan tekanan darah pada pasien end stage renal disease. Metode: Desain penelitian Literature  Review, online database adalah jurnal Science Direct, PubMed(NCBI), google scholar. Jurnal yang digunakan dalam kurun kurun waktu 2012-2020, pencarian menggunakan Populasi : pasien ESRD dengan hipertensi, intervensi :terapi non farmakologi, comparison: terapi komplomentar, outcome:penurunan tekanan darah, study design : literature review dan quasi experiment. Hasil: Didapatkan 6893 jurnal, diseleksi menggunakan kriteria inklusi dan ekslusi,melalui diagram prisma didapatkan menjadi 12 jurnal. Terapi non farmakologi yang digunakan adalah progressive muscel relaxation (4 jurnal); terapi massase (1 jurnal ); terapi music (4 jurnal); intradialitic exercise (4 jurnal) Kesimpulan: Terapi non farmakologi bermakna di dalam studi literature untuk menurunkan tekanan darah yang bekerja dengan prinsip relaksasi, berpengaruh dalam peningkatan hormon endorphin yang menyebabkan pembuluh darah berdilatasi sehingga tekanan darah mengalami penurunan. Kata Kunci : Terapi Non farmakologi, Hipertensi , End Stage Renal Disease   ABSTRACT   Background: End Stage Renal Disease (ESRD) can be caused by uncontrolled blood pressure (hypertension) or kidney disease can cause hypertension. Non-pharmacological therapy can help patients with blood pressure with minimal side effects. Objective: To conduct a literature study on the effectiveness of non-pharmacological therapies in reducing blood pressure of End Stage Renal Disease patients. Method: Literature Review research design, the data were obtained from online database such as Science Direct, PubMed (NCBI), and google scholar in the period of 2012-2020. The Population in this study was ESRD patients with hypertension and the intervention given were non-pharmacological therapies, comparison: commentary therapy, outcome: lowering blood pressure, study design: literature review and quasi experiment. Results: There were 6893 journals, selected using inclusion and exclusion criteria, through the PRISMA diagram they were narrowed down into 12 journals. The non-pharmacological therapies used were progressive muscle relaxation (4 journals); massage therapy (1 journal); music therapy (4 journals); and intradialytic exercise (4 journals). Conclusion: Non-pharmacological therapy is significant in literature studies to reduce blood pressure which works with the principle of relaxation. Further, it has an effect in increasing the endorphin hormone which causes blood vessels to dilate and lead to decreasing blood pressure.   Keywords: Non pharmacological, Hypertension, End Stage Renal Disease

The New Compound Heterozygous Mutation of NUP Nephropathy: Report of Two Cases and Literature Review

2021 ◽  
Author(s):  
Yuxin Pei ◽  
Liping Rong ◽  
Mengjie Jiang ◽  
Zhilang Lin ◽  
Cheng Cheng ◽  
...  
Keyword(s):  
Nephrotic Syndrome ◽  
Literature Review ◽  
End Stage Renal Disease ◽  
Compound Heterozygous ◽  
Founder Mutations ◽  
Steroid Resistant ◽  
Steroid Resistant Nephrotic Syndrome ◽  
Renal Manifestation ◽  
Stage Renal Disease ◽  
End Stage

Abstract Backgrounds: NUP nephropathy is identified as a rare monogenic cause of steroid-resistant nephrotic syndrome recently. To explore the relationship between NUP mutation and renal disorders, we provide two cases and a literature review of the genotypical and phenotypical features in patients with NUP nephropathy.Results: We reported two patients with newly diagnosed NUP nephropathy who carried a compound heterozygous mutations in NUP107 and NUP93 gene respectively. Both patients were diagnosed steroid-resistant nephrotic syndrome and progressed to end-stage renal disease in childhood. While the mutation c.1537+1G>A in NUP93 gene was previously described, the mutations c.460A>G and c.1085C>T in NUP107 gene and c.1472A>T in NUP93 gene were novel. We also summarized the phenotypic and genetic spectrum of NUP nephropathy in eighty-six reported patients who carried 50 different mutations in 6 NUP genes (NUP107, NUP93, NUP205, NUP85, NUP133, NUP160). The majority of them were Asians (66/86, 76.7%). The mutation c.2492A>C and c.1079-1083del in NUP107 had been identified as the founder mutations in East Asian[1-3], while c.1772G>T and c.1886A>G in NUP93 might be the founder mutations in Western Europe and Turkish respectively. Nephrotic syndrome was the most common renal manifestation (68/86, 79.1%). Although the renal prognosis was poor that 80.8% (59/73) of them developed end-stage renal disease within the first two decades, the outcome of renal transplantation in NUP nephropathy is better than patients with other steroid-resistant nephrotic syndrome. Focal segmental glomerulosclerosis was the most prevalent renal biopsy pathologic type (56/65, 86.1%). Various extra-renal manifestations were found in 44.8% (26/58) of patients. Neurological involvement was the most common extra-renal presentation (22/26, 84.6%), including microcephaly (13/22, 59.1%), intellectual disability (12/22, 54.5%), and global developmental delay (10/22, 45.5%). Diverse abnormalities of the facial appearance (8/26, 30.8%), short stature (5/26, 19.2%),and contain convergent strabismus (4/26, 15.4%) had also been reported. There are significant differences in extra-renal manifestations between different genomics. Conclusions: The renal manifestation of NUP nephropathy is highly consistent that most patients suffered early-onset SRNS with FSGS. More than half of the patients had extra-renal symptom concomitantly. Asians showed potential susceptibility to NUP nephropathy. Despite the limited reports, some genotype-phenotype correlations have been gradually revealed.

scholarly journals Restless Leg Syndrome in the Setting of Patients With End-Stage Renal Disease on Hemodialysis: A Literature Review

Cureus ◽  
2020 ◽  
Author(s):  
Srikala Kambampati ◽  
Shehnaz Wasim ◽  
Vishal Kukkar ◽  
Vanessa M Awad ◽  
Bilal Haider Malik
Keyword(s):  
Literature Review ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Restless Leg Syndrome ◽  
Stage Renal Disease ◽  
End Stage
Sign in / Sign up

Export Citation Format

Share Document