scholarly journals Mixed Neuroendocrine Carcinoma and Squamous Cell Carcinoma of the Colon: Case Report and Literature Review

2018 ◽  
Vol 12 (2) ◽  
pp. 240-246 ◽  
Author(s):  
Shinya Munakata ◽  
Yuta Murai ◽  
Akihiro Koizumi ◽  
Hisaki Kato ◽  
Riku Yamamoto ◽  
...  

Neuroendocrine carcinoma (NEC) of the colon is very rare, and squamous cell carcinoma (SCC) of colon cancer is rare. We recently treated a patient with both NEC and SCC that initially presented as multiple unresectable liver and lung metastases. A 68-year-old Japanese man was referred to our hospital because of diarrhea with descending colon cancer obstruction. He underwent a left colectomy. Based on immunohistochemistry results, we diagnosed mixed NEC and SCC, the primary lesion location of which was probably the lung in the final pathologic examination. He began systemic palliative chemotherapy with CDDP and CPT-11. After 3 months of treatment, shown the progressive disease, we started CDDP and VP-16. The patient was not eligible for additional chemotherapy after 2 months.

2018 ◽  
Vol 11 (3) ◽  
pp. 791-796 ◽  
Author(s):  
Tagore Sunkara ◽  
Megan E Caughey ◽  
Priyanka Makkar ◽  
Febin John ◽  
Vinaya Gaduputi

Overall, colorectal cancer is the third most commonly diagnosed cancer in both men and women, meaning that it is one of the more widely recognized preventable cancers. Instances of colorectal malignancies though are overwhelmingly attributable to adenocarcinoma. Colorectal cancers with components of squamous cell carcinoma represent a statistical anomaly. Here, we present the case of a 50-year-old male, who complained of abdominal pain and weight loss over a 3-month period of time. Biopsies from a colonoscopy ultimately revealed that this patient’s colon cancer consisted of both adenocarcinoma and squamous cell carcinoma, representing a truly exceptional pathology finding in a patient diagnosed with a colorectal cancer.


2005 ◽  
Vol 22 (5) ◽  
pp. 371-374 ◽  
Author(s):  
Silaja Yitta ◽  
Mike K. Liang ◽  
Russell Berman ◽  
Joseph J. Carter ◽  
Herman T. Yee ◽  
...  

Head & Neck ◽  
2018 ◽  
Author(s):  
Irene Arroyo‐Solera ◽  
Miguel Ángel Pavón ◽  
Xavier León ◽  
Montserrat López ◽  
Alberto Gallardo ◽  
...  

1989 ◽  
Vol 75 (6) ◽  
pp. 597-599 ◽  
Author(s):  
Marco Benasso ◽  
Alejandro Ferro ◽  
Almalina Bacigalupo ◽  
Salvatore Toma ◽  
Silvio Vitriolo ◽  
...  

The present paper reports a retrospective analysis of 16 patients with distant metastases from squamous cell carcinoma of the head and neck observed in our Institute in the last 10 years. Nine patients out of 16 underwent chemotherapy (7 patients), chemotherapy and radiotherapy (1 patient), or an alternating chemo-radiotherapy regimen (1 patient). The remaining 7 patients were not considered for a palliative treatment because of a poor performance status. Two complete responses, 2 partial responses, 2 stable diseases and 3 progressions were observed, with an overall response rate of 44 %. Chemotherapy, when administrable, showed a temporary effectiveness, at least in patients with lung metastases. The combination of cisplatin and 5-fluorouracil seems to maintain the efficacy already shown in patients with locally relapsed disease.


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