scholarly journals Suppurative Lymphadenitis after Radioactive Iodine Therapy for Graves’ Disease: A Rare Complication?

2019 ◽  
Vol 8 (6) ◽  
pp. 324-327 ◽  
Author(s):  
Shi Hui Junice Wong
Keyword(s):  
Radioactive Iodine ◽  
Rare Complication ◽  
Cervical Lymphadenopathy ◽  
Symptomatic Treatment ◽  
Graves Disease ◽  
Radioactive Iodine Therapy ◽  
Short Term ◽  
Cervical Lymphadenitis ◽  
Incision And Drainage ◽  
Radiation Induced

Background: Radioiodine (RAI) therapy for Graves’ disease is a well-accepted and effective treatment with a good side effect profile. Short-term adverse effects can occasionally include radiation-induced thyroiditis. To my knowledge, cervical lymphadenitis associated with RAI therapy for Graves’ disease has not been reported before. Case Report: A 38-year-old woman initially presented with uncontrolled thyrotoxicosis secondary to Graves’ disease. She subsequently received RAI therapy for her condition. Within a week, she developed painful bilateral cervical lymphadenopathy that progressed to abscess formation requiring incision and drainage. No other causes (neoplastic or infective) were found. Symptomatic treatment was instituted, and within 2 months the lymphadenitis resolved completely. Discussion: RAI therapy for Graves’ disease can sometimes cause radiation-induced thyroiditis but associated cervical lymphadenopathy or lymphadenitis has not been described. This may represent a continuum of the proinflammatory state induced by RAI manifesting as a rare but potentially morbid complication.

scholarly journals Short-term effect of radioactive iodine therapy on CXCL-10 production in Graves’ disease

2011 ◽  
Vol 34 (5) ◽  
pp. 262 ◽  
Author(s):  
Qing-Yu Dong ◽  
Shou-jie Li ◽  
Guan-Qi Gao ◽  
Xiao-meng Liu ◽  
Wen-xia Li ◽  
...  
Keyword(s):  
Radioactive Iodine ◽  
Dynamic Change ◽  
Strong Association ◽  
Serum Levels ◽  
Control Group ◽  
Thyroid Peroxidase ◽  
Graves Disease ◽  
Radioactive Iodine Therapy ◽  
Short Term ◽  
Pre Treatment

Purpose: To observe the short-term dynamic change in serum CXC chemokine ligand-10 (CXCL10) levels in patients with Graves' disease (GD) before and after iodine therapy and to analyze the relationship between CXCL10 levels and clinical disease indices. Methods: ELISA was used to determine serum levels of CXCL10 in 43 patients with GD shortly before radioiodine therapy and on days six, 14, and 60, post-therapy. Results: Patients with newly diagnosed GD showed significantly higher levels of serum CXCL10 compared with the control group (P < 0.01). The serum CXCL10 level increased slightly on day six after treatment of radioactive iodine (P < 0.01). There was no significant statistical difference in serum CXCL10 levels pre-treatment and on day 14 post-treatment. A significant reduction in serum CXCL10 level was observed on day 60 (P < 0.01). GD patients with exophthalmia showed higher serum CXCL10 level than GD patients without exophthalmia. No correlation was found between levels of CXCL10 and FT3, FT4 or TSH at any time point, but significant positive correlation was shown between thyroid peroxidase antibodies (TPOAb) and CXCL10 (r=0.50, P < 0.01). Conclusion: CXCL10 participates in the early inflammatory response after radioactive iodine therapy in patients with Graves’ disease and shows a strong association with the autoimmune process.

Abstract #1116 Radioactive Iodine Therapy for Graves Disease: What Predicts Failure?

2018 ◽  
Vol 24 ◽  
pp. 281-282
Author(s):  
Kalyani Regeti ◽  
Rajinikanth Yatavelli ◽  
Harsha Karanchi ◽  
Binod Pokhrel
Keyword(s):  
Radioactive Iodine ◽  
Graves Disease ◽  
Radioactive Iodine Therapy

Hyperparathyroidism subsequent to radioactive iodine therapy for Graves' disease

Head & Neck ◽  
2021 ◽  
Author(s):  
Richard H. Law ◽  
Daniel L. Quan ◽  
Andrew J. Stefan ◽  
Edward L. Peterson ◽  
Michael C. Singer
Keyword(s):  
Radioactive Iodine ◽  
Graves Disease ◽  
Radioactive Iodine Therapy

scholarly journals Anaplastic Thyroid Carcinoma Following Radioactive Iodine Therapy for Graves' Disease

2013 ◽  
Vol 28 (1) ◽  
pp. 61 ◽  
Author(s):  
Sun Hwa Kim ◽  
Hee Young Kim ◽  
Kwang Yoon Jung ◽  
Dong Seop Choi ◽  
Sin Gon Kim
Keyword(s):  
Thyroid Carcinoma ◽  
Radioactive Iodine ◽  
Anaplastic Thyroid Carcinoma ◽  
Graves Disease ◽  
Radioactive Iodine Therapy

scholarly journals Kikuchi-Fujimoto Disease: A Study Of 67 Cases From Coastal South India 

2020 ◽  
Author(s):  
Basavaprabhu Achappa ◽  
Nipuni Chamathka Herath ◽  
Jyoti Ramanath Kini ◽  
Ramesh Holla ◽  
Bodhi Sebastian ◽  
...  
Keyword(s):  
Clinical Presentation ◽  
Histopathological Examination ◽  
Cervical Lymphadenopathy ◽  
Symptomatic Treatment ◽  
Lymph Node Biopsy ◽  
Unknown Etiology ◽  
Extensive Literature ◽  
Cervical Lymphadenitis ◽  
Benign Condition ◽  
The Mean

Abstract Background Kikuchi-Fujimoto disease is a rare, benign condition, of unknown etiology, presenting as cervical lymphadenitis, usually tender and maybe associated with systemic symptoms. Despite the extensive literature on this disease, it continues to be misdiagnosed owing to its misleading clinical presentation. Results The mean age in our study was 26.9 (±11.3) years with a female majority of 65.7%. The clinical presentation of most cases was, tender swelling over the side of the neck ( n =50, 74.6%). On local examination, the mean length and width were 2.3 (±1.0) cm and 2.2 (±0.7) cm respectively. Histopathological examination revealed that most patients presented in the proliferative stage ( n =40, 59.7%). In 83.6% of the patients lymphadenopathy resolved in less than 2 months. Follow up of these patients over 9 months revealed that a vast majority of the patients underwent full recovery with symptomatic treatment ( n =42, 62.7%). Conclusions The disease is prevalent in young, female patients of Asian descent and often presents as cervical lymphadenopathy. Early diagnosis with excisional lymph node biopsy is crucial to avoid unnecessary investigations and treatment. Treatment is only symptomatic unless complicated, where steroid therapy is considered. Kikuchi’s disease has an excellent prognosis with almost no risk of fatality.

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