scholarly journals Multifocal Epithelioid Hemangioendothelioma Complicated with Disseminated Intravascular Coagulation

2021 ◽  
pp. 1490-1496
Author(s):  
Hiroaki Kimura ◽  
Norio Yamamoto ◽  
Katsuhiro Hayashi ◽  
Takashi Higuchi ◽  
Hiroyuki Tsuchiya
Keyword(s):  
Disseminated Intravascular Coagulation ◽  
Epithelioid Hemangioendothelioma ◽  
Antitumor Therapy ◽  
Tissue Mass ◽  
Vascular Neoplasm ◽  
Intravascular Coagulation ◽  
The Right ◽  
Term Management ◽  
Nafamostat Mesylate

Epithelioid hemangioendothelioma (EHE) is a rare malignant vascular neoplasm that requires long-term management. Several reports describe disseminated intravascular coagulation (DIC) associated with angiosarcoma, but no association with EHE has been reported. We encountered a patient with DIC complicated by multifocal EHE. The patient was an 83-year-old woman with spinal lesions, small lung nodules, and a soft tissue mass in the right buttock. The tumor was biopsied and diagnosed as EHE. The patient received pain control therapy without antitumor therapy. One month later, DIC developed with tumor progression. DIC subsided with nafamostat mesylate infusion, and oral apixaban was administered. DIC was managed for 5 months until the patient died of brain metastases. This is the first report of a patient with DIC complicated by EHE. It should be noted that progression of EHE can cause DIC. We were able to manage DIC using anticoagulant agents.

scholarly journals Acute Promyelocytic Leukemia: Results of Treatment by Daunorubicin

Blood ◽  
1973 ◽  
Vol 41 (4) ◽  
pp. 489-496 ◽  
Author(s):  
Jean Bernard ◽  
Marise Weil ◽  
Michel Boiron ◽  
Claude Jacquillat ◽  
Georges Flandrin ◽  
...  
Keyword(s):  
Acute Promyelocytic Leukemia ◽  
Median Duration ◽  
Disseminated Intravascular Coagulation ◽  
Promyelocytic Leukemia ◽  
The Other ◽  
Intravascular Coagulation ◽  
Results Of Treatment

Abstract Daunorubicin induces complete remissions in about 50% of patients with acute promyelocytic leukemia. The median duration of these remission is 26 mo. Failures are mainly due to hemorrhages as a result of disseminated intravascular coagulation during the first 5 days (25%) or due to sepsis during the second and third week (25%). Long-term survivals are more frequent than in the other acute granulocytic leukemias.

Disseminated Intravascular Coagulation (DIC) during Long-Term Bypass

1986 ◽  
Vol 32 (1) ◽  
pp. 542-545
Author(s):  
LILJ UZIEL ◽  
MASSIMO M. CUGNO ◽  
AGOSTINA COLOMBO ◽  
ANGELO AGOSTONI ◽  
FRANCESCA ROSSI ◽  
...  
Keyword(s):  
Disseminated Intravascular Coagulation ◽  
Intravascular Coagulation

scholarly journals A Case of Vanishing Metastatic Mass: Right Atrial Mass in the Setting of Primary Epithelioid Hemangioendothelioma of the Spine

2018 ◽  
Vol 11 (2) ◽  
pp. 534-540 ◽  
Author(s):  
Eshan Patel ◽  
P. Kancharla ◽  
B.K. Surapaneni ◽  
K. Hennrick ◽  
M. Goldfinger ◽  
...  
Keyword(s):  
Clinical Presentation ◽  
Epithelioid Hemangioendothelioma ◽  
The Body ◽  
Right Atrial ◽  
Low Grade ◽  
Vascular Neoplasm ◽  
Right Atrial Mass ◽  
Progression Of Disease ◽  
The Right ◽  
Age And Sex

Epithelioid hemangioendothelioma (EHE) is a rare low-grade vascular neoplasm that is characterized as intermediate between benign hemangioma and high-grade angiosarcoma affecting 1 in 1,000,000 people worldwide. It has been described throughout the body with lung, liver, skin, and bone being the most frequent sites. Primary EHE of the spine has been reported in 56 cases so far with no correlation of age and sex. Our case highlights a rare clinical presentation, etiopathogenesis, diagnosis, and treatment of EHE of the spine with metastasis to the right atrium. This is the first documented case of EHE of the spine with metastatic spread to the heart treated with bevacizumab leading to resolution of the heart metastatic mass. Further studies are warranted to develop a treatment formula for this rare tumor, to consider combination chemotherapy and new adjuvant targeted immunotherapies to prevent progression of disease.

Mediastinal Epithelioid Hemangioendothelioma Invading Superior Vena Cava: A Case Report and Review of Literature

2019 ◽  
Vol 15 (3) ◽  
pp. 349-352
Author(s):  
Su Hong Kim ◽  
Young Seon Kim ◽  
Min Hye Jang ◽  
Hee Jung Kwon
Keyword(s):  
Superior Vena Cava ◽  
Superior Vena ◽  
Vena Cava ◽  
Anterior Mediastinum ◽  
Epithelioid Hemangioendothelioma ◽  
Vascular Neoplasm ◽  
Case Presentation ◽  
Contrast Enhanced ◽  
The Right ◽  
Brachiocephalic Veins

Introduction: Epithelioid Hemangioendothelioma (EHE) is a rare vascular neoplasm. Common locations of EHE are the bone, soft tissue, liver, and lung, but the mediastinal location is extremely rare. Few cases of mediastinal EHE, invading the Superior Vena Cava (SVC) have been reported. </P><P> Case Presentation: We report a case of a 21-year-old man with EHE invading the SVC, which was incidentally detected on performing chest radiography. A contrast-enhanced chest Computed Tomography (CT) scan demonstrated a well-defined, oval mass located on the right side of the anterior mediastinum. The mass showed homogeneous enhancement with punctate calcifications, and it invaded the SVC at the confluence area of the right and left brachiocephalic veins. Conclusion: Mediastinal EHE invading the SVC may present as a homogeneously enhancing mass with punctate calcifications. It should be added to the differential diagnosis of tumors of the mediastinum. Accurate preoperative diagnosis of EHE is critical for surgical planning; therefore, knowledge of the radiologic features of EHE is important.

scholarly journals Epithelioid Hemangioendothelioma of Cavernous Sinus

2017 ◽  
Vol 06 (03) ◽  
pp. 206-209
Author(s):  
Raj Chandran ◽  
Jyotsna Nair ◽  
Krishna Balachandran ◽  
Bhanu Rajmohan
Keyword(s):  
Cavernous Sinus ◽  
Cranial Nerve ◽  
Epithelioid Hemangioendothelioma ◽  
Rare Tumor ◽  
Cranial Nerve Involvement ◽  
Sixth Cranial Nerve ◽  
Vascular Neoplasm ◽  
Headache Pain ◽  
The Right ◽  
Uncommon Location

AbstractEpithelioid hemangioendothelioma is an uncommon vascular neoplasm. It is rare in the intracranial location. Its occurrence in the region of cavernous sinus is reported only once. Here, we report a case of 49-year-old man who presented with a headache, pain in the right eye, diplopia, and ptosis due to third and sixth cranial nerve involvement. Imaging showed an enhancing lesion in the region of cavernous sinus on the right side. Pterional craniotomy, combined extradural and intradural approach, and subtotal excision of the tumor was done. Histopathology and immunohistochemistry were suggestive of epithelioid hemangioendothelioma which is a rare tumor in this location. We report this case because of its rarity and uncommon location.

scholarly journals Cutaneous actinomycosis and long-term management through using oral and topical antibiotics: A case report

2018 ◽  
Vol 8 (4) ◽  
Author(s):  
Ali Hassan Najmi ◽  
Ibrahim Hassan Najmi ◽  
Mosa Mohmmed Hassan Tawhari ◽  
Khadija Hafed Sawadi ◽  
Khaled Ahamed Hassan Khbrani ◽  
...  
Keyword(s):  
Case Report ◽  
Bacterial Infection ◽  
Rare Entity ◽  
Central Hospital ◽  
Topical Antibiotics ◽  
Surgical Department ◽  
The Right ◽  
Local Examination ◽  
Term Management

Actinomycosis is a subacute or chronic suppurative bacterial infection which caused because of filamentous gram-positive, anaerobic to microaerophilic nonacid fast bacilli primarily of the genus Actinomyces that normally colonize the mouth, colon, and vagina. Primary cutaneous actinomycosis is a rare entity and is generally associated with trauma. A 61- year-old Yemeni male firstly presented to the surgical department in King Fahd Central Hospital with multiple swelling, petted lesions and boring of sensation in the right foot. Local examination showed multiple erythematous nodules and plaques with discharge in the right leg, and active sinus was not determined.

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