scholarly journals EFFECT OF SELENIUM-CHROME-LIPID SUBSTANCE FROM CHLORELLA VULGARIS BIEJ. ON OXIDATIVE STATUS OF RATS

Author(s):  
O. Ya. Lukashiv ◽  
O. I. Bodnar ◽  
H. B. Vinyarskа ◽  
V. V. Hrubinko

By incubation unicellular alga Chlorella vulgaris Biej. in aquaculture with sodium selenite and chrome (III) sulphate there was received and allocated stable lipid and selenium, chrome-lipid substance and studied their effects on oxidative status in healthy rats experiment. Putting substances at a dose of 1.85 mсg of selenium, chrome 1.1 mcg and 0.5 mg lipid per 1 ml of 1 % aqueous starch slurry body in healthy rats every day for 14 days suppressed prooxidative processes activated antioxidant status by glutation system by reduction of catalase and superoxidedismutase activity partly in experimental animals in the liver and in blood serum.

2015 ◽  
Vol 17 (4) ◽  
Author(s):  
H. B. Vinyarska ◽  
P. H. Lykhatskyi ◽  
O. I. Bodnar ◽  
L. S. Fira ◽  
V. V. Grubinko

<p>There were obtained and allocated stable selen-lipid and selen-zinc-lipid substances in a result of incubationof unicellular algae Chlorella vulgaris Biej. In aquaculture with sodium selenite and zinc sulfate their influence on oxidative and energetic status of healthy rat was investigated. There were suppressed prooxidative processes,activated antioxidant status, succinate dehydrogenase and cytochrome oxidase activity and glutamate dehydrogenase way of formation of glutamate were increased when substance at a dose of 0.4 mcg of selenium, 2.5 mcg of zinc<br />and 0.5 mg of lipid per 1 ml of 1 % starch-water suspensions was introduced in organisme of healthy rats. Also it contributed of formation and functioning of the active components of the antioxidant system – catalase, ceruloplasmin,<br />reduction glutathione in a liver and in a blood serum of experimental animals.</p>


Author(s):  
N. N. Malyutina ◽  
A. F. Bolotova ◽  
R. B. Eremeev ◽  
A. Zh. Gilmanov ◽  
D. Yu. Sosnin

Introduction. The overwhelming number of publications contains only data on the content of individual antioxidants, but not on the overall antioxidant activity of the blood in patients with vibration disease.The aim of the study was to determine the total antioxidant activity of blood serum in patients with vibration disease.Materials and methods. Th e main group consisted of 30 people diagnosed with “Vibration disease” of 1 degree (n=21) and 2 degrees (n=9). Th e control group consisted of 30 clinically healthy men, comparable in age with the main group (p=0.66). Th e total activity of antioxidant systems of blood plasma was evaluated photometrically using the test system “Total antioxidant status-Novo” (“Vector-best”, Russia).Results. The indicator of the total antioxidant status (TAS) was 1,038±0.232 mmol/l in the examined main group, against 1,456±0.225 mmol/l in the examined control group (p<0.000001). Th e coefficient of variation (CV) in patients with vibration disease was 22.35%, 1.45 times higher than in the control group (15.45%). In the main group there was a positive correlation between age and TAS (R=0.525), in the control group there was no such relationship (R=0.095). Th e degree of decrease depended on the severity of vibration disease.Conclusions. 1. The development of vibration disease is accompanied by a decrease in the antioxidant status of blood serum. 2. Th e degree of decrease in the antioxidant status of blood serum correlates with the severity of vibration disease. 3. Reduction of TAS can serve as a pathogenetic justification of the need to include drugs and/or biologically active additives with antioxidant activity in therapy


1997 ◽  
Vol 265 (1) ◽  
pp. 77-84 ◽  
Author(s):  
Deniz S. Erdinçler ◽  
Arzu Seven ◽  
Figen Inci ◽  
Tanju Beǧer ◽  
Gülden Candan

1993 ◽  
Vol 12 ◽  
pp. 27-28 ◽  
Author(s):  
J.S. Koenig ◽  
E. Bulant ◽  
W. Druml ◽  
M. Fischer ◽  
P. Balcke ◽  
...  

1989 ◽  
Vol 17 (3) ◽  
pp. 492-492 ◽  
Author(s):  
ROBERTA J. WARD ◽  
JATINDER JUTLA ◽  
TIMOTHY J. PETERS

2020 ◽  
Vol 28 (2) ◽  
pp. 145-152
Author(s):  
Șadiye-Ioana Scripcariu ◽  
Andreea Avasiloaiei ◽  
Demetra Socolov ◽  
Elena Mihălceanu ◽  
Daniela-Cristina Dimitriu ◽  
...  

AbstractAim: The aim of this study is to identify correlations between total antioxidant status values of mothers and their infants and compare these values in accordance to the presence or absence of intrauterine growth restriction.Material and methods: This is a prospective, comparative study performed over a period of 3 years on a number of 52 infants and their mothers. Thirty-six of them had intrauterine growth restriction and 16 were appropriate for their gestational age and were used for comparative purposes. General information regarding the mother, infant and pregnancy were recorded. In addition, total antioxidant status was assessed from blood samples, taken right before delivery from mothers and from the cord blood in infants.Results: We found significant differences between total antioxidant status both between mothers and neonates with IUGR (intrauterine growth restriction) versus without IUGR (p=0.018, and p<0.001, respectively). In addition, in both groups, there was a significant direct correlation between maternal and neonatal values of serum total antioxidant status (TAS) (p<0.001).In conclusion, we can say that TAS values, as an important marker of the oxidative status of patients, are correlated with the presence of IUGR and values recorded from blood samples of the mother may be predictive for the oxidative status of the infant, thus of IUGR.


Sign in / Sign up

Export Citation Format

Share Document