scholarly journals Utilização da cirurgia de mohs no tratamento de neoplasias Malignas não melanocíticas da pele

2021 ◽  
Vol 54 (3) ◽  
Author(s):  
João Augusto Gomes de Souza Monteiro de Brito ◽  
Lucas da Silva Lopes ◽  
Ana Luísa Gross Rodrigues ◽  
Caio Vinicius Botelho Brito
Keyword(s):  
Pubmed Central

Objetivo: Averiguar a efetividade da utilização da cirurgia de MOHS no manejo de tumores cutâneos tipo não melanoma em comparação a outros métodos de terapia. Métodos: O estudo consiste em uma revisão sistemática, cuja coleta de artigos ocorreu nas bases de dados MEDLINE, PubMed Central (PMC), LILACS e SciELO, utilizando os termos “Cirurgia de MOHS”, “Câncer de pele”, “Ensaio clínico”, excluindo “melanoma”. Resultados: Do total de 132 artigos identificados, foram considerados elegíveis 11. A análise dos artigos demonstrou que a CMM, comparada a outros métodos, apresentou resultados estéticos melhores, além de menor grau de complicações em tumores recorrentes e um custo/benefício variável com o país onde foi feita operação. A CMM também apresentou menores índices de recorrência em todos os estudos. Conclusão: No geral, a cirurgia de MOHS se mostrou um método terapêutico promissor. No entanto, existem ainda poucos estudos comparativos sobre a eficácia da CMM e os que existem se concentram em poucas regiões do mundo.

A contribuição visual para o controle postural

2001 ◽  
Vol 18 (3) ◽  
pp. 370-379 ◽  
Author(s):  
Antonio Vinicius Soares
Keyword(s):  
Pubmed Central ◽  
Contrôle Postural

Objetivo. O objetivo desta revisão de literatura foi levantar e discutir estudos sobre a contribuição visual para o controle postural, aspecto este, notoriamente necessário para o controle motor como um todo. Método. Foram revisados livros e artigos indexados nas bases de dados Scielo, Lilacs, PubMed Central, Medscape Neurology, publicados de 1987 a 2009, em inglês e português. Resultados. Revisaram-se os aspectos mais relevantes sobre a visão como um sistema sensorial especial; a sua relação com os sistemas somatossensorial e vestibular; os centros neurais integradores e as vias descendentes para o controle postural. Em seguida, foram abordados aspectos quanto à contribuição visual para o sistema de controle postural ao longo do desenvolvimento, pesquisas sobre o controle postural em cegos e em pacientes com distúrbios neurológicos. Conclusão. Embora a Teoria Ecológica proposta por James Gibson ainda considerada nova no campo da fisioterapia, os achados teóricos e de pesquisa poderão, com o tempo, avançar o suficiente para explicar como o sistema musculoesquelético é utilizado para restringir e organizar habilidades funcionais.

Questions to the Article of research output and international cooperation among countries during the COVID-19 pandemic (Preprint)

2020 ◽  
Author(s):  
Shu-Chun Kuo ◽  
Tsair-Wei Chien ◽  
Willy Chou
Keyword(s):  
Citation Analysis ◽  
International Cooperation ◽  
Web Of Science ◽  
Research Output ◽  
Visual Representations ◽  
Scientometric Analysis ◽  
Medical Subject Headings ◽  
Pubmed Central ◽  
The Us ◽  
Circle Diagram

UNSTRUCTURED We read with great interest the study by Grammes et al. on research output and international cooperation among countries during the COVID-19 pandemic. The paper is a quantitative study using scientometric analysis instead of a qualitative research using citation analysis. A total of 7,185 publications were extracted from Web of Science Core Collection (WoS) with keywords of “covid19 OR covid-19 OR sarscov2 OR sars-cov-2” as of July 4, 2020. We replicated a citation analysis study to extract abstracts from Pubmed Central(PMC) with similar keywords mentioned above and obtained 35,421 articles relevant to COVID-10 matching their corresponding number of citation in PMC. one hundred top-cited atricles were selected and compared on diagrams. Social network analysis combined with citation numbers in articles was performed to analyze international cooperation among countries. The results were shown on a world map instead of the circle diagram in the previous study. A Sankey diagram was applied to highlight entities(e.g., countries, article types, medical subject headings, and journals) with the most citations. Authors from Chian dominated citations in these 100 top-cited articles rather than the US in publications addressed in the previous study. Both visual representations of the world map and Sankey diagram were provided to readers with a better understanding of the research output and international cooperation among countries during the COVID-19 pandemic

scholarly journals Security and Privacy Requirements for Electronic Consent

2021 ◽  
Vol 20 (2) ◽  
pp. 1-24
Author(s):  
Stef Verreydt ◽  
Koen Yskout ◽  
Wouter Joosen
Keyword(s):  
Security And Privacy ◽  
Inclusion Criteria ◽  
Comprehensive Overview ◽  
Privacy And Security ◽  
Pubmed Central ◽  
Privacy Requirements ◽  
Development Lifecycle ◽  
Main Challenge ◽  
Security Challenges ◽  
Server Systems

Electronic consent (e-consent) has the potential to solve many paper-based consent approaches. Existing approaches, however, face challenges regarding privacy and security. This literature review aims to provide an overview of privacy and security challenges and requirements proposed by papers discussing e-consent implementations, as well as the manner in which state-of-the-art solutions address them. We conducted a systematic literature search using ACM Digital Library, IEEE Xplore, and PubMed Central. We included papers providing comprehensive discussions of one or more technical aspects of e-consent systems. Thirty-one papers met our inclusion criteria. Two distinct topics were identified, the first being discussions of e-consent representations and the second being implementations of e-consent in data sharing systems. The main challenge for e-consent representations is gathering the requirements for a “valid” consent. For the implementation papers, many provided some requirements but none provided a comprehensive overview. Blockchain is identified as a solution to transparency and trust issues in traditional client-server systems, but several challenges hinder it from being applied in practice. E-consent has the potential to grant data subjects control over their data. However, there is no agreed-upon set of security and privacy requirements that must be addressed by an e-consent platform. Therefore, security- and privacy-by-design techniques should be an essential part of the development lifecycle for such a platform.

scholarly journals Neuroimaging Findings in Adolescents and Young Adults with Anorexia Nervosa: A Systematic Review

Children ◽  
2021 ◽  
Vol 8 (2) ◽  
pp. 137
Author(s):  
Kalliopi Kappou ◽  
Myrto Ntougia ◽  
Aikaterini Kourtesi ◽  
Eleni Panagouli ◽  
Elpis Vlachopapadopoulou ◽  
...  
Keyword(s):  
Systematic Review ◽  
Young Adults ◽  
Anorexia Nervosa ◽  
Large Scale ◽  
Temporal Cortex ◽  
Adolescents And Young Adults ◽  
Pubmed Central ◽  
Executive Control Network ◽  
Young Females ◽  
Weight Restoration

Background: Anorexia nervosa (AN) is a serious, multifactorial mental disorder affecting predominantly young females. This systematic review examines neuroimaging findings in adolescents and young adults up to 24 years old, in order to explore alterations associated with disease pathophysiology. Methods: Eligible studies on structural and functional brain neuroimaging were sought systematically in PubMed, CENTRAL and EMBASE databases up to 5 October 2020. Results: Thirty-three studies were included, investigating a total of 587 patients with a current diagnosis of AN and 663 healthy controls (HC). Global and regional grey matter (GM) volume reduction as well as white matter (WM) microstructure alterations were detected. The mainly affected regions were the prefrontal, parietal and temporal cortex, hippocampus, amygdala, insula, thalamus and cerebellum as well as various WM tracts such as corona radiata and superior longitudinal fasciculus (SLF). Regarding functional imaging, alterations were pointed out in large-scale brain networks, such as default mode network (DMN), executive control network (ECN) and salience network (SN). Most findings appear to reverse after weight restoration. Specific limitations of neuroimaging studies in still developing individuals are also discussed. Conclusions: Structural and functional alterations are present in the early course of the disease, most of them being partially or totally reversible. Nonetheless, neuroimaging findings have been open to many biological interpretations. Thus, more studies are needed to clarify their clinical significance.

Suicide methods in South Asia over two decades (2001–2020)

2021 ◽  
pp. 002076402110157
Author(s):  
S M Yasir Arafat ◽  
Syeda Ayat-e-Zainab Ali ◽  
Vikas Menon ◽  
Fahad Hussain ◽  
Daniyal Shabbir Ansari ◽  
...  
Keyword(s):  
Sri Lanka ◽  
South Asia ◽  
South Asian ◽  
English Language ◽  
Public Health Problem ◽  
Asian Countries ◽  
Pubmed Central ◽  
Suicide Methods ◽  
Search Terms ◽  
Quantitative Studies

Background: Suicide is a global preventable public health problem. About a quarter of all suicides in the world occur in South Asia. As means restriction is an important suicide prevention strategy, gaining knowledge of the common suicide methods and their changing trends in each country and region is crucial. Aims: We aimed to assess the suicide methods in South Asian countries over the last two decades. Methods: A search was performed in PubMed, PubMed Central, Scopus, and Google Scholar with the search terms. Original articles of quantitative studies, published in the English language, from 2001 to 2020, with full-accessible text, that rank different methods of suicide in eight South Asian countries, were included. Results: A total of 68 studies were found eligible for review. The Maximum number of studies were found from India ( n = 38), followed by Bangladesh ( n = 12), Pakistan ( n = 9), Sri Lanka ( n = 6), and Nepal ( n = 3). Hanging ( n = 40, 55.8%) and poisoning ( n = 24, 35.3%) were the two most common suicide methods reported, in that order. Hanging followed by poisoning were the commonest suicide methods in Bangladesh, India, and Pakistan while in Sri Lanka, poisoning was the preferred method to hanging. There is a decline in suicide by poisoning and an increase in suicide by hanging in Sri Lanka, Bangladesh, and India. Although hanging is still the commonest method in Pakistan, the use of firearms is growing in recent years (2011–2020). Conclusions: There is a steady decline in the incidence of suicides by poisoning following pesticide regulations in South Asian countries. However, there is heterogeneity of study methods, probable under-reporting of suicide, and lack of robust suicide data.

scholarly journals Publishing group offers peer review on PubMed Central

Nature ◽  
10.1038/45875 ◽  
1999 ◽  
Vol 402 (6758) ◽  
pp. 110-110 ◽  
Author(s):  
Declan Butler
Keyword(s):  
Peer Review ◽  
Pubmed Central ◽  
Publishing Group

scholarly journals Database citation in supplementary data linked to Europe PubMed Central full text biomedical articles

2015 ◽  
Vol 6 (1) ◽  
pp. 1 ◽  
Author(s):  
Şenay Kafkas ◽  
Jee-Hyub Kim ◽  
Xingjun Pi ◽  
Johanna R McEntyre
Keyword(s):  
Full Text ◽  
Supplementary Data ◽  
Pubmed Central

scholarly journals Disease stability and extended dosing under anti-VEGF treatment of exudative age-related macular degeneration (AMD) — a meta-analysis

2021 ◽  
Author(s):  
Justus G. Garweg ◽  
Christin Gerhardt
Keyword(s):  
Macular Degeneration ◽  
Meta Analysis ◽  
Subretinal Fluid ◽  
Age Related Macular Degeneration ◽  
Pubmed Central ◽  
Age Related ◽  
Interval Extension ◽  
Second Year ◽  
Mean Differences

Abstract Purpose To assess disease stability (absence of intra- and/or subretinal fluid) and the portion of eyes being capable to extend their treatment interval to ≥ 12 weeks in exudative age-related macular degeneration (AMD). Methods A systematic literature search was performed in NCBI, PubMed, CENTRAL, and ClinicalTrials.gov to identify clinical studies reporting treatment outcomes for ranibizumab, aflibercept, and brolucizumab in exudative AMD under a treat-and-extend protocol and a follow-up of ≥ 12 months. Weighted mean differences and subgroup comparisons were used to integrate the different studies. Results This meta-analysis refers to 29 published series, including 27 independent samples and 5629 patients. In the pooled group, disease stability was reported in 62.9% and 56.0%, respectively, after 12 and 24 months of treatment, whereas treatment intervals were extended to ≥ 12 weeks in 37.7% and 42.6%, respectively. Ranibizumab, aflibercept, and brolucizumab differed regarding their potential to achieve disease stability (56.3%, 64.5%, and 71.5% after 12, and 50.0%, 52.7% and 75.7% after 24 months; p = < 0.001) and to allow an interval extension to ≥ 12 weeks (28.6%, 34.2%, and 53.3% after 12, and 34.2%, 47.7%, and 41.7% after 24 months; p = < 0.001). Conclusion The portion of eyes achieving disease stability regressed in the second year, whereas the portion of eyes under a ≥ 12-week interval increased. This discrepancy may reflect the challenges in balancing between under-treatment and a reduced treatment burden.

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