scholarly journals Effect of Oxygen Breathing on Pacing-Induced Angina Pectoris and other Manifestations of Coronary Insufficiency

Circulation ◽  
1972 ◽  
Vol 45 (4) ◽  
pp. 837-844 ◽  
Author(s):  
MATIJA HORVAT ◽  
SHINJI YOSHIDA ◽  
RAVI PRAKASH ◽  
HAROLD S. MARCUS ◽  
H. J.C. SWAN ◽  
...  
2019 ◽  
Vol 9 (3) ◽  
pp. 197-206
Author(s):  
Kanika Patel ◽  
Mahfoozur Rahman ◽  
Vikas Kumar ◽  
Amita Verma ◽  
Dinesh Kumar Patel

Background: Ammi visnaga commonly known as ‘honey plant, tooth pick fruit, bisnaga and khella’ is an important plant of Apiaceae family. It is an annual herb found in Europe, Asia, North Africa, Latin America and in India. Carrot, parsnip, celery, coriander, anise, caraway, cumin, parsley and dill are some other plants of the same family i.e., ‘Apiaceae’. Fruits of Ammi visnaga (A. visnaga) are medicinally used as a strong photosensitizer, diaphoretic, carminative and antispasmodic agents. Objective: A. visnaga has been used for the treatment of bronchial asthma, coronary insufficiency, angina pectoris, psoriasis, renal colic and ureteric stones. Visnagin (C13H10O4) is a ‘furanochromone derivative’ which is the main active constituent’s of A. visnaga. Visnagin is used for the treatment of low blood-pressure, angina pectoris and kidney stone. It also has neuroprotective and antiinflammatory activity. Moreover, visnagin also treat whooping cough, ureter and bile duct, gall bladder and renal colic, tumors and epileptic seizures. Methods: This review summarizes data’s regarding the biological importance, pharmacological uses and medicinal importance of A. visnaga and their important active constituent’s “visnagin”. Moreover, the detailed pharmacological aspects of visnagin were presented in this review. Further various analytical techniques used for the extraction and isolation of visnagin were also discussed. Studies related to the pharmacological profile of the plants and their active phytoconstituents are one of the leading areas of research. Conclusion: This review will be beneficial to the scientific society to understand the importance of A. visnaga plant and their active constituents ‘visnagin’for the development of alternative tools to treat disorders in the future.


2017 ◽  
Vol 02 (04) ◽  
pp. 094-098
Author(s):  
Meenakshi Kadiyala ◽  
Rameshwar Roopchandar ◽  
Chandrshekaran Krishnaswamy

AbstractBecause of improvement in survival from coronary artery disease and increasing life expectancy of the population, chronicity and resistance to therapy have become growing problems confronting the cardiologist. Refractory angina pectoris is an entity based on clinical diagnosis, and it refers to recurrent and sustained chest pain more than 3 months duration caused by coronary insufficiency that is unamenable to conventional modalities of treatment, including drugs, percutaneous coronary interventions, or coronary bypass grafting. Individuals with this entity may have an impaired quality of life, with recurrent angina, poor general health and psychological distress impairing functional and productive sustenance. A multitude of therapeutic options exists for patients with refractory angina pectoris, and randomized trials have shown them to be reasonably effective in reducing symptoms, though further research is warranted.


1962 ◽  
Vol 17 (2) ◽  
pp. 233-238 ◽  
Author(s):  
Zora J. Griffo ◽  
Albert Roos

The effect of oxygen breathing on pulmonary compliance was studied in paralyzed, artificially ventilated dogs and in two normal subjects. 1) In the dogs and the human subjects the course of compliance during oxygen breathing for periods of 1frac12–2 hr following hyperinflation was compared with that during air breathing. 2) In dogs compliance after apnea on oxygen (following hyperinflation) for frac12–7 min was compared with that after apnea on air. Intrapulmonary pressure during apnea was atmospheric. 3) In the human subjects the course of compliance was followed during air breathing for 50–70 min, preceded by hyperinflation and immediately followed by oxygen breathing for 80–100 min. In none of these three sets of studies did oxygen breathing affect the course or magnitude of pulmonary compliance. It is concluded that breathing pure oxygen at atmospheric pressure for several hours does not enhance the development of pulmonary atelectasis in normal subjects. Submitted on July 3, 1961


1979 ◽  
Vol 47 (5) ◽  
pp. 1112-1117 ◽  
Author(s):  
W. E. Truog ◽  
M. P. Hlastala ◽  
T. A. Standaert ◽  
H. P. McKenna ◽  
W. A. Hodson

The effect of oxygen breathing on shunt and ventilation-perfusion ratios (VA/Q) in anesthetized rats was studied using a modification of the multiple inert gas elimination technique. Base-line analyses showed hypoxemia in some animals breathing room air (arterial O2 tensions 48-70 Torr) associated with intrapulmonary shunts ranging from 0 to 22%, and variable low VA/Q lung regions as determined by calculation of the inert gas arterial-alveolar difference curve. Of nine rats that breathed 100% oxygen for 30 min, three showed increases in shunt (0% leads to 19%, 1.5% leads to 16%, 11% leads to 40%). These three animals had larger preexisting low VA/Q regions than the six that developed no shunt (0.48 +/- 0.15 vs. 0.17 +/- 0.03 (mean +/- SD); P less than 0.05). These data are compatible with the theory of absorption atelectasis. This study documents the usefulness of the inert gas elimination technique for studying pulmonary gas exchange problems in small animals.


1965 ◽  
Vol 20 (5) ◽  
pp. 855-858 ◽  
Author(s):  
Samuel T. Giammona ◽  
Donald Kerner ◽  
Stuart Bondurant

To evaluate the effects of oxygen breathing at atmospheric pressure on pulmonary surfactant, cats, rabbits, and rats were continuously kept in 98% oxygen until death occurred. Pulmonary surfactant was extracted by mincing of the lung and by foam fractionation of the lung. Surface tension of the extracts was measured on a Wilhelmy balance. Lung extracts prepared by both methods from the cats and rabbits kept in oxygen had greater surface tension than lung extracts from control animals. Surface tension of extracts prepared by foam fractionation of lungs of rats kept in oxygen did not differ from that of extracts of lungs of control rats, whereas surface tension of extracts prepared by mincing lungs of rats kept in oxygen had minimum surface tension greater than that of lung extracts of control rats. This species difference in the effects of oxygen breathing on pulmonary surfactant may reflect a difference in the pathogenesis of oxygen intoxication. oxygen intoxication; surface tension Submitted on October 19, 1964


2006 ◽  
Vol 121 (3) ◽  
pp. 823-828 ◽  
Author(s):  
P. R. B. Caldwell ◽  
S. T. Giammona ◽  
W. L. Lee ◽  
S. Bondurant

1944 ◽  
Vol 27 (6) ◽  
pp. 803-816 ◽  
Author(s):  
Arthur M. Master ◽  
Harry L. Jaffe ◽  
Simon Dack ◽  
Arthur Grishman

Thorax ◽  
1974 ◽  
Vol 29 (6) ◽  
pp. 673-677 ◽  
Author(s):  
H. Lecerof

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