scholarly journals Exercise cardiac output is maintained with advancing age in healthy human subjects: cardiac dilatation and increased stroke volume compensate for a diminished heart rate.

Circulation ◽  
1984 ◽  
Vol 69 (2) ◽  
pp. 203-213 ◽  
Author(s):  
R J Rodeheffer ◽  
G Gerstenblith ◽  
L C Becker ◽  
J L Fleg ◽  
M L Weisfeldt ◽  
...  
1996 ◽  
Vol 58 (1-2) ◽  
pp. 44-50 ◽  
Author(s):  
Michio Watanabe ◽  
Yutaka Shimada ◽  
Shinya Sakai ◽  
Naotoshi Shibahara ◽  
Harumi Matsuda ◽  
...  

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Hisao Hiraba ◽  
Motoharu Inoue ◽  
Kanako Gora ◽  
Takako Sato ◽  
Satoshi Nishimura ◽  
...  

We previously found that the greatest salivation response in healthy human subjects is produced by facial vibrotactile stimulation of 89 Hz frequency with 1.9 μm amplitude (89 Hz-S), as reported by Hiraba et al. (2012, 20011, and 2008). We assessed relationships between the blood flow to brain via functional near-infrared spectroscopy (fNIRS) in the frontal cortex and autonomic parameters. We used the heart rate (HRV: heart rate variability analysis in RR intervals), pupil reflex, and salivation as parameters, but the interrelation between each parameter and fNIRS measures remains unknown. We were to investigate the relationship in response to established paradigms using simultaneously each parameter-fNIRS recording in healthy human subjects. Analysis of fNIRS was examined by a comparison of various values between before and after various stimuli (89 Hz-S, 114 Hz-S, listen to classic music, and “Ahh” vocalization). We confirmed that vibrotactile stimulation (89 Hz) of the parotid glands led to the greatest salivation, greatest increase in heart rate variability, and the most constricted pupils. Furthermore, there were almost no detectable differences between fNIRS during 89 Hz-S and fNIRS during listening to classical music of fans. Thus, vibrotactile stimulation of 89 Hz seems to evoke parasympathetic activity.


2006 ◽  
Vol 291 (4) ◽  
pp. H1768-H1772 ◽  
Author(s):  
C. T. Paul Krediet ◽  
Johannes J. van Lieshout ◽  
Lysander W. J. Bogert ◽  
Rogier V. Immink ◽  
Yu-Sok Kim ◽  
...  

Vasovagal syncope is the most common cause of transient loss of consciousness, and recurrent vasovagal fainting has a profound impact on quality of life. Physical countermaneuvers are applied as a means of tertiary prevention but have so far only proven useful at the onset of a faint. This placebo-controlled crossover study tested the hypothesis that leg crossing increases orthostatic tolerance. Nine naïve healthy subjects [6 females, median age 25 yr (range 20–41 yr), mean body mass index 23 (SD 2)] were subjected to passive head-up tilt combined with a graded lower body negative pressure challenge (20, 40, and 60 mmHg) determining orthostatic tolerance thrice, in randomized order: 1) control, 2) with leg crossing, and 3) with oral placebo. Blood pressure (Finometer), heart rate, and changes in thoracic blood volume (impedance), stroke volume, and cardiac output (Modelflow) were followed during orthostatic stress. Primary outcome was time to presyncope (systolic blood pressure ≤85 mmHg, heart rate ≥140 beats/min). With leg crossing, orthostatic tolerance increased from 26 ± 2 to 34 ± 2 min (placebo 23 ± 3 min, P < 0.001). During leg crossing, mean arterial pressure (81 vs. 81 mmHg) and cardiac output (95 vs. 94% supine) remained unchanged; heart rate increase was lower (13 vs. 18 beats/min, P < 0.05); stroke volume was higher (79 vs. 74% supine, P < 0.05); and there was a trend toward lower thoracic impedance. Leg crossing increases orthostatic tolerance in healthy human subjects. As a measure of prevention, it is a worthwhile addition to the management of vasovagal syncope.


2009 ◽  
Vol 43 (1) ◽  
pp. 41-45 ◽  
Author(s):  
A Manzo ◽  
Y Ootaki ◽  
C Ootaki ◽  
K Kamohara ◽  
K Fukamachi

2002 ◽  
Vol 95 (3) ◽  
pp. 965-972 ◽  
Author(s):  
Fabrice Dosseville ◽  
Sebastien Moussay ◽  
Jacques Larue ◽  
Antoine Gauthier ◽  
Damien Davenne

To identify whether spontaneous motor rhythm is influenced by external or internal events and whether this rhythm fluctuates across the day in parallel with heart rate diurnal variations, we simultaneously recorded heart rate and spontaneous motor rate before and after a pedaling task performed five times a day by 10 healthy human subjects. Each subject performed a Spontaneous Motor Tempo, i.e., a finger-tapping task, at a comfortable and spontaneous cadence. Pre- and postexercise Spontaneous Motor Tempo was measured as well as heart rate. There were diurnal variations in Spontaneous Motor Tempo. Both measures increased significantly after pedaling, suggesting that cardiac and spontaneous rhythms are influenced simultaneously after a moderate exercise. Also, finger-taps occurred most frequently around the initiation of the heart systole. These results suggest that a putative internal clock might regulate Spontaneous Motor Tempo and that cardiac rhythm might influence this tempo


1999 ◽  
Vol 88 (03) ◽  
pp. 106-111 ◽  
Author(s):  
G Ruiz ◽  
J-L Torres ◽  
O Michel ◽  
R Navarro

AbstractWe record ECGs from healthy human subjects during 24-h long intervals, using ambulatory equipment. We calculate from the data various parameters, searching for those that change in a clear and systematic way under a homoepathic stimulus, (Strophantus hispidus 30 c). The energy fraction at high frequencies in the power spectrum of heart rate variability fulfills this condition, and we are able to interpret our results in a way consistent with the information on this medicine in the homeopathic Materia Medica.


2016 ◽  
Vol 11 (10) ◽  
pp. 1934578X1601101
Author(s):  
Iris Stappen ◽  
Anna-Sofie Hoelzl ◽  
Olivera Randjelovic ◽  
Juergen Wanner

The influence of essential ginger oil ( Zingiberis aetheroleum from Zingiber officinale Roscoe) on blood pressure, heart rate and subjective well-being was investigated after inhalation and dermal application on healthy human subjects in two experiments. Additionally a GC-MS analysis of the tested oil is given. The essential oil exhibited a high amount of citral (19.4%). α-Zingiberene (17.4%), camphene (7.8%), trans, trans-α-farnesene (6.8%) and β-bisabolene (5.8%) were also prominent constituents. Compared with the control condition an activating effect was observed for ginger oil in the inhalation experiment.


Sign in / Sign up

Export Citation Format

Share Document