scholarly journals Effects of Essential Oil Fragrances and Preferences thereof on Blood Pressure and Heart Rate in Healthy Human Subjects

2009 ◽  
Vol 6 (3) ◽  
pp. 137-142
Author(s):  
Hiroko MORI ◽  
Akiko KOBAYASHI ◽  
Sanae KIKKAWA ◽  
Hitoshi YAMASHITA
2016 ◽  
Vol 11 (10) ◽  
pp. 1934578X1601101
Author(s):  
Iris Stappen ◽  
Anna-Sofie Hoelzl ◽  
Olivera Randjelovic ◽  
Juergen Wanner

The influence of essential ginger oil ( Zingiberis aetheroleum from Zingiber officinale Roscoe) on blood pressure, heart rate and subjective well-being was investigated after inhalation and dermal application on healthy human subjects in two experiments. Additionally a GC-MS analysis of the tested oil is given. The essential oil exhibited a high amount of citral (19.4%). α-Zingiberene (17.4%), camphene (7.8%), trans, trans-α-farnesene (6.8%) and β-bisabolene (5.8%) were also prominent constituents. Compared with the control condition an activating effect was observed for ginger oil in the inhalation experiment.


1996 ◽  
Vol 58 (1-2) ◽  
pp. 44-50 ◽  
Author(s):  
Michio Watanabe ◽  
Yutaka Shimada ◽  
Shinya Sakai ◽  
Naotoshi Shibahara ◽  
Harumi Matsuda ◽  
...  

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Hisao Hiraba ◽  
Motoharu Inoue ◽  
Kanako Gora ◽  
Takako Sato ◽  
Satoshi Nishimura ◽  
...  

We previously found that the greatest salivation response in healthy human subjects is produced by facial vibrotactile stimulation of 89 Hz frequency with 1.9 μm amplitude (89 Hz-S), as reported by Hiraba et al. (2012, 20011, and 2008). We assessed relationships between the blood flow to brain via functional near-infrared spectroscopy (fNIRS) in the frontal cortex and autonomic parameters. We used the heart rate (HRV: heart rate variability analysis in RR intervals), pupil reflex, and salivation as parameters, but the interrelation between each parameter and fNIRS measures remains unknown. We were to investigate the relationship in response to established paradigms using simultaneously each parameter-fNIRS recording in healthy human subjects. Analysis of fNIRS was examined by a comparison of various values between before and after various stimuli (89 Hz-S, 114 Hz-S, listen to classic music, and “Ahh” vocalization). We confirmed that vibrotactile stimulation (89 Hz) of the parotid glands led to the greatest salivation, greatest increase in heart rate variability, and the most constricted pupils. Furthermore, there were almost no detectable differences between fNIRS during 89 Hz-S and fNIRS during listening to classical music of fans. Thus, vibrotactile stimulation of 89 Hz seems to evoke parasympathetic activity.


2009 ◽  
Vol 43 (1) ◽  
pp. 41-45 ◽  
Author(s):  
A Manzo ◽  
Y Ootaki ◽  
C Ootaki ◽  
K Kamohara ◽  
K Fukamachi

Circulation ◽  
1984 ◽  
Vol 69 (2) ◽  
pp. 203-213 ◽  
Author(s):  
R J Rodeheffer ◽  
G Gerstenblith ◽  
L C Becker ◽  
J L Fleg ◽  
M L Weisfeldt ◽  
...  

PLoS ONE ◽  
2021 ◽  
Vol 16 (3) ◽  
pp. e0248428
Author(s):  
Jumpei Mano ◽  
Keita Saku ◽  
Hiroyuki Kinoshita ◽  
Hiroshi Mannoji ◽  
Shigehiko Kanaya ◽  
...  

Background The increase of blood pressure (BP) variability (BPV) is recognized as an important additional cardiovascular risk factor in both normotensive subjects and hypertensive patients. Aging-induced atherosclerosis and autonomic dysfunction impair the baroreflex and, in turn, augment 24-hour BPV. In small and large animal experiments, impaired baroreflex steepens the slope of the power spectrum density (PSD) of continuous BP in the frequency range of 0.01 to 0.1 Hz. Although the repeated oscillometric BP recording over 24 hours or longer is a prerequisite to quantify BPV in humans, how the very short-term continuous BP recording reflects BPV remains unknown. This study aimed to evaluate the impact of aging on the very short-term (30-min) BPV in healthy human subjects by frequency analysis. Methods We recorded continuous BP tonometrically for 30 min in 56 healthy subjects aged between 28 and 85 years. Considering the frequency-dependence of the baroreflex dynamic function, we estimated the PSD of BP in the frequency range of 0.01 to 0.1 Hz, and compared the characteristics of PSD among four age groups (26–40, 41–55, 56–70 and 71–85 years). Results Aging did not significantly alter mean and standard deviation (SD) of BP among four age groups. PSD was nearly flat around 0.01 Hz and decreased gradually as the frequency increased. The slope of PSD between 0.01 and 0.1 Hz was steeper in older subjects (71 years or older) than in younger subjects (55 years or younger) (p < 0.05). Conclusions Aging steepened the slope of PSD of BP between 0.01 and 0.1 Hz. This phenomenon may partly be related to the deterioration of the baroreflex in older subjects. Our proposed method to evaluate very short-term continuous BP recordings may contribute to the stratification of BPV.


2014 ◽  
Vol 112 (2) ◽  
pp. 183-192 ◽  
Author(s):  
Erik K. Grasser ◽  
Abdul Dulloo ◽  
Jean-Pierre Montani

Overconsumption of sugar-sweetened beverages has been implicated in the pathogenesis of CVD. The objective of the present study was to elucidate acute haemodynamic and microcirculatory responses to the ingestion of sugary drinks made from sucrose, glucose or fructose at concentrations similar to those often found in commercial soft drinks. In a randomised cross-over study design, twelve young healthy human subjects (seven men) ingested 500 ml tap water in which was dissolved 60 g of either sucrose, glucose or fructose, or an amount of fructose equivalent to that present in sucrose (i.e. 30 g fructose). Continuous cardiovascular monitoring was performed for 30 min before and at 60 min after ingestion of sugary drinks, and measurements included beat-to-beat blood pressure (BP) and impedance cardiography. Additionally, microvascular endothelial function testing was performed after iontophoresis of acetylcholine and sodium nitroprusside using laser Doppler flowmetry. Ingestion of fructose (60 or 30 g) increased diastolic and mean BP to a greater extent than the ingestion of 60 g of either glucose or sucrose (P< 0·05). Ingestion of sucrose and glucose increased cardiac output (CO; P< 0·05), index of contractility (P< 0·05) and stroke volume (P< 0·05), but reduced total peripheral resistance (TPR; P< 0·05), which contrasts with the tendency of fructose (60 and 30 g) to increase resistance. Microvascular endothelial function did not differ in response to the ingestion of various sugary drinks. In conclusion, ingestion of fructose, but not sucrose, increases BP in healthy human subjects. Although sucrose comprises glucose and fructose, its changes in TPR and CO are more related to glucose than to fructose.


2002 ◽  
Vol 95 (3) ◽  
pp. 965-972 ◽  
Author(s):  
Fabrice Dosseville ◽  
Sebastien Moussay ◽  
Jacques Larue ◽  
Antoine Gauthier ◽  
Damien Davenne

To identify whether spontaneous motor rhythm is influenced by external or internal events and whether this rhythm fluctuates across the day in parallel with heart rate diurnal variations, we simultaneously recorded heart rate and spontaneous motor rate before and after a pedaling task performed five times a day by 10 healthy human subjects. Each subject performed a Spontaneous Motor Tempo, i.e., a finger-tapping task, at a comfortable and spontaneous cadence. Pre- and postexercise Spontaneous Motor Tempo was measured as well as heart rate. There were diurnal variations in Spontaneous Motor Tempo. Both measures increased significantly after pedaling, suggesting that cardiac and spontaneous rhythms are influenced simultaneously after a moderate exercise. Also, finger-taps occurred most frequently around the initiation of the heart systole. These results suggest that a putative internal clock might regulate Spontaneous Motor Tempo and that cardiac rhythm might influence this tempo


1991 ◽  
Vol 10 (6) ◽  
pp. 411-418 ◽  
Author(s):  
Neil A. Minton ◽  
John A. Henry

1 Five healthy human subjects were given, in single-blind fashion, either (a) 625 mg theophylline orally, followed 4 h later, by a 40 min infusion of adenosine (40 μg kg -1 min-1 for 5 min, 60 μg kg-1 min -1 for 5 min and 80 μg kg-1 min-1 for 30 min), or (b) 625 mg theophylline orally followed by 0.9% sodium chloride infusion, or (c) placebo theophylline tablets followed by adenosine infusion. 2 All five subjects experienced adverse effects during adenosine infusion, mainly at the higher infusion rates; two subjects also experienced chest pain but not during combined treatment with theophylline and adenosine. 3 Diastolic blood pressure (DBP) rose by 16.5 mmHg ( P < 0.001) following treatment with theophylline only, fell by 24.5 mmHg ( P < 0.001) during the adenosine infusion after placebo theophylline and remained unchanged during the adenosine infusion following theophylline. Pulse rate rose by 12 min -1 ( P < 0.01) during adenosine infusion following placebo, but not after theophylline alone or theophylline and adenosine combined. 4 The respiratory rate fell by 6 min-1 ( P < 0.01) during treatment with adenosine only, being lower than for the two treatments containing theophylline ( P < 0.05). 5 Plasma potassium and magnesium fell by 0.25 mmol I-1 ( P < 0.001) and 0.037 mmol I-1 ( P < 0.05), respectively, during treatment with theophylline only, but these effects were not altered by infusion of adenosine. 6 This study has demonstrated interactions between theophylline and adenosine on diastolic blood pressure and respiratory rate, but no interaction on metabolic parameters. Adenosine infusion is unlikely to be of value in the management of theophylline toxicity, but its effects on theophylline-induced cardiac arrhythmias remain unexplored.


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