scholarly journals Management of patient compliance in the treatment of hypertension. Report of the NHLBI Working Group.

Hypertension ◽  
1982 ◽  
Vol 4 (3) ◽  
pp. 415-423 ◽  

2009 ◽  
Vol 5 (1) ◽  
pp. 52
Author(s):  
Michel Burnier ◽  

It is well-documented that reducing blood pressure (BP) in hypertensive individuals reduces the risk of cardiovascular events. Despite this, many patients with hypertension remain untreated or inadequately treated and fail to reach the recommended BP goals. Suboptimal BP control, while arising from multiple causes, is often due to poor patient compliance and/or persistence, and results in a significant healthcare and socioeconomic burden. By reducing the pill burden, the use of single-pill combination therapies for the treatment of hypertension has the potential to increase patient compliance and persistence. Compared with antihypertensive monotherapies, single-pill combinations may offer equivalent or better efficacy and the same or improved tolerability. As a result, single-pill combinations have the potential to reduce both the cardiovascular event rates and the non-drug healthcare costs associated with hypertension.



1995 ◽  
Vol 47 (6) ◽  
pp. 477-481 ◽  
Author(s):  
J. -M. Detry ◽  
◽  
P. Block ◽  
G. De Backer ◽  
J. -P. Degaute ◽  
...  


1976 ◽  
Vol 51 (s3) ◽  
pp. 559s-561s
Author(s):  
K. P. O'brien ◽  
E. J. W. Stephens

1. Patients with moderate to severe hypertension were studied during a 12 weeks period, while taking a slow-release formulation of oxprenolol once daily, in a dose equal to their previous total daily dose of oxprenolol given in divided doses. 2. There were no significant differences between blood pressure at the beginning and end of the 12 weeks period. 3. Once-daily dosage offers advantages of patient compliance.



1982 ◽  
Vol 10 (5) ◽  
pp. 351-356
Author(s):  
Diego González

This multicentre, open study was conducted in 263 hypertensive patients from six different countries by seventeen investigators. The results confirm the efficacy and safety of nadolol, used alone or in combination therapy in the treatment of hypertension, even inpatients in whom previous antihypertensive therapy with other drugs was unsatisfactory. The study also demonstrated that nadolol can effectively replace a variety of other antihypertensive agents, and, because of once a day dosage, can enhance patient compliance and produce better therapeutic responses.



1975 ◽  
Vol 26 ◽  
pp. 21-26

An ideal definition of a reference coordinate system should meet the following general requirements:1. It should be as conceptually simple as possible, so its philosophy is well understood by the users.2. It should imply as few physical assumptions as possible. Wherever they are necessary, such assumptions should be of a very general character and, in particular, they should not be dependent upon astronomical and geophysical detailed theories.3. It should suggest a materialization that is dynamically stable and is accessible to observations with the required accuracy.



1979 ◽  
Vol 44 ◽  
pp. 349-355
Author(s):  
R.W. Milkey

The focus of discussion in Working Group 3 was on the Thermodynamic Properties as determined spectroscopically, including the observational techniques and the theoretical modeling of physical processes responsible for the emission spectrum. Recent advances in observational techniques and theoretical concepts make this discussion particularly timely. It is wise to remember that the determination of thermodynamic parameters is not an end in itself and that these are interesting chiefly for what they can tell us about the energetics and mass transport in prominences.



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