scholarly journals What Are High-Flow and Low-Flow Oxygen Delivery Systems?

Stroke ◽  
2005 ◽  
Vol 36 (10) ◽  
pp. 2066-2067 ◽  
Author(s):  
Ritesh Agarwal ◽  
Dheeraj Gupta
Author(s):  
William Poncin ◽  
Grégory Reychler ◽  
Christophe De Terwangne ◽  
Matthieu Marnette ◽  
Frédéric Duprez

BMJ Open ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. e037964
Author(s):  
Shahan Waheed ◽  
Nazir Najeeb Kapadia ◽  
Muhammad Faisal Khan ◽  
Salima Mansoor Kerai ◽  
Ahmed Raheem ◽  
...  

IntroductionApnoeic oxygenation is a process of delivering continuous oxygen through nasal cannula during direct laryngoscopy. The oxygen that is delivered through these nasal cannulas is either low flow or high flow. Although the effectiveness of apnoeic oxygenation has been shown through systematic reviews and randomised controlled trials, a comparison of high-flow versus low-flow oxygen delivery has not been tested through a superiority study design. In this study we propose to assess the effectiveness of giving low-flow oxygen with head side elevation versus high-flow oxygen with head side elevation against the usual practice of care in which no oxygen is provided during direct laryngoscopy.Methods and analysisThis will be a three-arm study instituting a block randomisation technique with a sample size of 46 in each arm (see table 1). Due to the nature of the intervention, no blinding will be introduced. The primary outcomes will be lowest non-invasive oxygen saturation measurement during direct laryngoscopy and during the 2 min after the placement of the tube and the first pass success rate. The intervention constitutes head side elevation up to 30° for improving glottis visualisation together with low-flow or high-flow oxygen delivery through nasal cannula to increase safe apnoea time for participants undergoing endotracheal intubation. Primary analysis will be intention to treat.Ethics and disseminationThe study is approved by the Ethical Review Committee of Aga Khan University Hospital (2019-0726-2463). The project is an institution University Research Committee grant recipient 192 002ER-PK. The results of the study will be disseminated among participants, patient communities and healthcare professionals in the institution through seminars, presentations and emails. Further, the findings will be published in a highly accessed peer-reviewed medical journal and will be presented at both national and international conferences.Trial registration numberClinicalTrials.gov Registry (NCT04242537).


2015 ◽  
Vol 58 (1) ◽  
pp. 49-52 ◽  
Author(s):  
Pinar Uygur ◽  
Sedat Oktem ◽  
Perran Boran ◽  
Engin Tutar ◽  
Gulnur Tokuc

2016 ◽  
Vol 105 (8) ◽  
pp. e368-e372 ◽  
Author(s):  
Gregorio P. Milani ◽  
Anna M. Plebani ◽  
Elisa Arturi ◽  
Danila Brusa ◽  
Susanna Esposito ◽  
...  

1989 ◽  
Vol 25 (6) ◽  
pp. 370-371
Author(s):  
G. R. WILLIAMS ◽  
I. B. MASTERS ◽  
M. A. HARRIS

1989 ◽  
Vol 17 (1) ◽  
pp. 78-82
Author(s):  
P. A. Johnson ◽  
A. K. Outhred ◽  
R. F. Raper ◽  
M. McD. Fisher

The performance of ten high-flow Bird blenders (3M Company) was assessed to ascertain the stability of the oxygen delivery both over time and within a single respiratory cycle. Blended oxygen concentrations were assessed for both continuous low flow and for intermittent flow with variable tidal volumes as is seen with mechanical ventilation. Studies were repeated after the addition of a high flow bleed from the blender via a T-piece. We observed clinically significant variations in the oxygen concentrations delivered by several blenders when the relationship between air and oxygen supply pressures varied. This variability was greatest when the air and oxygen pressures were nearly equal. When the line pressures were stable, mixed oxygen concentrations were constant but variations in oxygen delivery were found within individual breath cycles. This could be explained by postulating that at the initiation of flow from the blender a small pocket of unblended gas (pure air or pure oxygen) was issued by the blender before the balancing mechanism stabilised to deliver the desired oxygen concentration. This variability of oxygen delivery may have considerable impact on the measurement of oxygen consumption using the open circuit technique. The addition of a high flow bleed completely ablated this blender-derived variation in oxygen delivery.


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