Abstract MP41: Health-related Quality of Life and Risk of Hypertension in the Community: A Prospective Analysis from the Western New York Health Study

Circulation ◽  
2014 ◽  
Vol 129 (suppl_1) ◽  
Author(s):  
Saverio Stranges ◽  
Lisa Rafalson ◽  
Richard Donahue
Keyword(s):  
Quality Of Life ◽  
Blood Pressure ◽  
New York ◽  
Health Status ◽  
Health Study ◽  
Health Related Quality ◽  
Sf 36 ◽  
Related Quality ◽  
Health Related

Health-related Quality of Life and Risk of Hypertension in the Community: A Prospective Analysis from the Western New York Health Study Background: Measures of quality of life and health status are strong predictors of mortality and morbidity outcomes including cardiovascular disease (CVD). However, prospective epidemiological evidence from population-based studies on the potential impact of these measures on hypertension risk is scant. Objective: We sought to examine the independent role of measures of quality of life and health status on the risk of incident hypertension in a community-based sample from Western New York. Methods: A longitudinal analysis, over 6 years of follow-up, among 946 women and men (mean age 54.3 years) from the community, who were free of hypertension, CVD, and diabetes at the baseline examination, in the Western New York Health Study (WNYHS). Baseline variables included socio-demographics, anthropometrics, blood pressure, biomarker data, major behavioural risk factors, and measures of quality of life and health status, such as the physical and mental health component summaries of the short form-36 questionnaire (SF-36). Incident hypertension was defined as blood pressure > or =140/90 or on antihypertensive medication at the follow-up visit. Results: The cumulative six year incidence of hypertension was 22.6% (214/942). In bivariate analyses, there were several baseline correlates of incident hypertension, including age, BMI, and baseline blood pressure levels in both sexes; whereas cigarette smoking, change in BMI, family history of hypertension, and the SF-36 physical score were all significantly associated with hypertension only among women. After multivariate adjustment, cigarette use at baseline (OR: 2.96, 1.35, 6.51), family history of hypertension (OR: 2.59, 1.52-4.42), BMI change since baseline (OR: 1.18, 1.06-1.31), and the SF-36 physical score (OR: 0.97, 0.94-0.99 for a unit change) were the only significant predictors of hypertension independent of age and baseline blood pressure levels in women. Conclusions: Results from this study suggest that measures of health-related quality of life may represent independent predictors of hypertension risk, at least among women, above and beyond the role of traditional risk factors, such as age, smoking, body weight, and familial predisposition.

Abstract 13633: Predictors of Mental and Physical Health Outcomes of Patients Undergoing an Appointment-based Cardiac Rehabilitation Program

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Catherine Xie ◽  
Sean Fournier ◽  
Susan Hiller ◽  
Joyce Oen Hsiao ◽  
Rachel P Dreyer
Keyword(s):  
Quality Of Life ◽  
Health Status ◽  
Cardiac Rehabilitation ◽  
General Health ◽  
Health Related Quality ◽  
Sf 36 ◽  
Patient Reported ◽  
Related Quality ◽  
Health Related

Introduction: Cardiac rehabilitation (CR) is an evidence-based program to improve secondary prevention outcomes for patients with cardiovascular disease (CVD). Lower health-related quality of life is a known risk factor for worse CVD outcomes. We examined the effects of a patient-driven appointment-based CR program on health-related quality of life. Methods: We utilized data from the Yale New-Haven Health (YNHH) CR program over a 6-year period (2012-2017). Data was collected on patient demographics, clinical characteristics and socioeconomic status. The Medical Outcome Short-Form General Health Survey (SF-36) was used to measure general health status. We evaluated SF-36 score changes pre and post CR with paired T-tests and conducted logistic regression analysis to examine predictors of improvements in health-related quality of life. Results: Over the 6-year study period, a total of 2,135 patients (27.9% women, mean age 65±12 years) were enrolled in the CR program. Patients demonstrated significant improvements in both the SF-36 physical, mental and health transition components (P<0.001) (Table) . In particular, patients had significant improvement in the social functioning domain (measures limitations patients see in their ability to participate in social activities due to physical/emotional issues), with an increase of 23.3 points out of 100. Physician-reported patient stress and/or depression on intake medical exam were significant negative predictors for improvement in the total SF-36 score (OR 0.23, 95% CI 0.08-0.80, P=0.021), with the effect driven largely by its impact on the physical component of SF-36 (OR 0.27, 95% CI 0.09-0.83, P=0.022). Conclusion: We demonstrated that a novel appointment-based CR program produced improvements in patient-reported health-related quality of life. Appointment-based CR could be a viable alternative for patients who prefer more scheduling flexibility, to optimize health status improvement and CVD outcomes.

scholarly journals Comparisons of Health-Related Quality of Life and Impact Factors in Patients with Depression and Schizophrenia

2020 ◽  
Author(s):  
Chonghua Wan ◽  
Jingjing Zhang ◽  
Yan Lin ◽  
Keying Zhao ◽  
Jiahong Luo ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Health Status ◽  
Impact Factors ◽  
Health Related Quality ◽  
Schizophrenia Group ◽  
Depression Group ◽  
Sf 36 ◽  
Related Quality ◽  
Health Related

Abstract Background: Depression and schizophrenia are the global common causes worldwide of long-term and devastating disability, which significantly impact the patient quality of life. This paper is aimed to analyze and compare the health-related quality of life (HRQOL) of patients with Depression and Schizophrenia, determine main impact factors of their HRQOL with these two diseases and try to distinct the difference of impacts at socio-demographic，socioeconomic and medical level. Methods: 204 out-patients and in-patients diagnosed Depression or Schizophrenia according to Chinese classification and diagnostic criteria of mental disorders (CCMD-3) were sampled, who were volunteering to participate and can understand the meaning of questionnaires with accordance of the included criteria. The Health survey questionnaire (SF-36) and self-administered measurements were used to appraisal the subjective health status, the disease characteristics and other relevant medical potential predictors of participants. Results: All of the domain scores of SF-36 of patients with Depression and Schizophrenia are both lower than healthy people and there are significant differences in all domains, compared with depression group, most domains of SF-36 in Schizophrenia group are lower besides the body pain (BP) and social function (SF), and are difference in domains of role physical (RP) and mental health (MH) between two patient groups. For depression group, the predictors of unmarried status, subject change of health status and depression degree are correlated to HRQOL in PCS, the predictors of unmarried status, ethnicity and duration of disease are correlated to HRQOL in MCS. For schizophrenia group, predictors of subjective change of health status, family annual income, educational level, severity degree and ethnicity are associated with HRQOL in PCS, only predictor of ethnicity is associated with HRQOL in MCS. Conclusion: The HRQOL of patients was likely be impacted by the factors at both socio-demographic and medical level, but the functions of the same factors were different between depression and schizophrenia.

scholarly journals Brazilian normative data for the Short Form 36 questionnaire, version 2

2013 ◽  
Vol 16 (4) ◽  
pp. 889-897 ◽  
Author(s):  
Josué Laguardia ◽  
Mônica Rodrigues Campos ◽  
Claudia Travassos ◽  
Alberto Lopes Najar ◽  
Luiz Antonio dos Anjos ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Health Status ◽  
Rural Areas ◽  
Normative Data ◽  
Short Form ◽  
Health Related Quality ◽  
Sf 36 ◽  
Related Quality ◽  
Health Related

METHODS: The study Pesquisa Dimensões Sociais das Desigualdades (PDSD) (Social Dimensions of Inequalities) involves 12,423 randomly selected Brazilian men and women aged 18 years old or more from urban and rural areas of the five Brazilian regions, and the information collected included the SF-36 as a measure of health-related quality of life. This provided a unique opportunity to develop age and gender-adjusted normative data for the Brazilian population. RESULTS: Brazilian men scored substantially higher than women on all eight domains and the two summary component scales of the SF-36. Brazilians scored less than their international counterparts on almost all of SF-36 domains and both summary component scales, except on general health status (US), pain (UK) and vitality (Australia, US and Canada). CONCLUSION: The differences in the SF-36 scores between age groups, genders and countries confirm that these Brazilian norms are necessary for comparative purposes. The data will be useful for assessing the health status of the general population and of patient populations, and the effect of interventions on health-related quality of life.

scholarly journals Evaluation of health-related quality of life in patients with Cushing's syndrome with a new questionnaire

2008 ◽  
Vol 158 (5) ◽  
pp. 623-630 ◽  
Author(s):  
S M Webb ◽  
X Badia ◽  
M J Barahona ◽  
A Colao ◽  
C J Strasburger ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Clinical Practice ◽  
Health Status ◽  
General Health ◽  
Health Related Quality ◽  
General Health Status ◽  
Sf 36 ◽  
Related Quality ◽  
Health Related

Chronic exposure to hypercortisolism has significant impact on patient's health and health-related quality of life (HRQoL), as demonstrated with generic questionnaires. We have developed a disease-generated questionnaire to evaluate HRQoL in patients with Cushing's syndrome (CS; CushingQoL).ObjectiveValidate the CushingQoL questionnaire in patients with CS in clinical practice conditions.DesignObservational, international, cross-sectional study.MethodsA total of 125 patients were recruited by 14 investigators from Spain, France, Germany, The Netherlands, and Italy over a 2-month period. Clinical and hormonal data were collected and correlated with results of the generic short form 36 (SF-36) questionnaire, a question on self-perceived general health status and the CushingQoL score.ResultsA total of 107 patients were pituitary-dependent and 18 adrenal-dependent CS; 104 (83%) were females, mean age 45 years (range 20–73 years); 39 (31%) were currently hypercortisolemic; and 47 (38%) adrenal insufficient. In clinical practice, CushingQoL was feasible (117; 94% of patients fully responded to the questionnaire in a mean time of 4 min), reliable (Crohnbach's α=0.87), and valid (factorial analysis demonstrated unidimensionality and Rasch analysis lead to a final version with 12 items). A significant (P<0.001) correlation was observed between CushingQoL score and patients self-perceived general health status and dimensions of SF-36 (Pearson's correlation coefficient ≥0.597). Patients with current hypercortisolism scored worse (lower) than those without (44±22 vs 56±21, P=0.004). Linear regression analysis identified female gender and hypercortisolism as significant predictors for worse QoL.ConclusionCushingQoL is useful to evaluate HRQoL in patients with CS and correlates with clinical parameters.

Mental Health Status and Health-Related Quality of Life among Systemic Lupus Erythematosus (SLE) Patients in Thailand: A Multi-Site Study

2020 ◽  
Vol 103 (11) ◽  
pp. 1185-1193
Keyword(s):  
Quality Of Life ◽  
Mental Health ◽  
Health Status ◽  
Lupus Erythematosus ◽  
Self Esteem ◽  
Mental Health Status ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

Background: The systemic lupus erythematosus (SLE) patients oftentimes suffer from both physical and psychosocial challenges that may lead to low health-related quality of life (HRQoL). However, limited research has been done in this area. Objective: To examined mental health status and HRQoL among SLE patients in Thailand. Materials and Methods: The present study was a cross-sectional study conducted at the rheumatology clinic of four major hospitals in Thailand. The paper-based questionnaire consisted of demographic, health history such as depression, anxiety, stress Scale (DASS-21), and the Rosenberg self-esteem scale (RSE), and the disease-specific Lupus Quality of Life scale (LupusQoL). Depending on the variable’s level of measurement such as categorical or continuous, Spearman’s Rho or Pearson’s product moment correlation coefficients were used to explore the relationships among the variables. Hierarchical multiple regression was used to identify the predictors of LupusQoL. Results: Among the 387 participants, many might have experienced depression, anxiety, and stress (30%, 51%, and 29%, respectively). Self-esteem among the participants was good (31.8 out of 40). All eight domains of LupusQoL were affected with intimate relationship domain being impacted the most. The overall LupusQoL was significantly associated with the number of prescribed medications (r=–0.23), depression (r=–0.70), anxiety (r=–0.58), stress (r=–0.67), and self-esteem (r=0.59), p<0.001. Significant predictors of the overall LupusQoL were mental health status (depression, anxiety, and stress) and self-esteem, F (3, 81)=43.10, p<0.001, adjusted R²=0.60. Conclusion: SLE patients should be holistically assessed in both physical and psychological aspects. In addition to proper medical treatments, healthcare providers should use a multidisciplinary team approach to resolve the patients’ psychosocial issues, which in turn, may increase the patients’ quality of life. Self-care education may be necessary to help the patients manage the condition and decrease the number of medications. Keywords: Mental health, Quality of life, SLE, Thailand

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