Abstract 201: Results of the ANSWER Trial Using the PulseRider for the Treatment of Broad-necked, Bifurcation Aneurysms

Stroke ◽  
2017 ◽  
Vol 48 (suppl_1) ◽  
Author(s):  
Alex M Spiotta
Keyword(s):  
United States ◽  
Clinical Trial ◽  
The United States ◽  
San Jose ◽  
Neck Size ◽  
Aneurysm Embolization ◽  
Wide Neck ◽  
The U.S

Background: The safety and probable benefit of the PulseRider ® (Pulsar Vascular, San Jose, CA) for the treatment of broad-necked, bifurcation aneurysms was studied in the context of the prospective, non-randomized, single arm clinical trial - the Adjunctive Neurovascular Support of Wide-neck aneurysm Embolization and Reconstruction Trial (ANSWER). Objective: We present the results of the United States cases employing the PulseRider ® device as part of the ANSWER clinical trial. Methods: Aneurysms treated with the PulseRider ® device among U.S. sites enrolling in the ANSWER trial were prospectively studied and the results are summarized. Aneurysms arising at either the carotid terminus or basilar apex that were relatively broad necked were considered candidates for inclusion into the ANSWER study. Results: 34 patients were enrolled (29 female and 5 male) with a mean age of 60.9 years (27 basilar apex and 7 carotid terminus). Mean aneurysm height ranged from 2.4 to 15.9 mm with a mean neck size of 5.2 mm (range 2.3 - 11.6 mm). In all patients the device was delivered and deployed. Immediate Raymond I or II occlusion was achieved in 82.4% and progressed to 87.9% at six month follow up. A modified Rankin Score of 2 or less was seen in 94% of patients at 6 months. Conclusions: The results from the U.S. cases of the ANSWER trial demonstrate that the Pulse Rider® device is safe and effective as for the treatment of bifurcation aneurysms arising at the basilar apex or carotid terminus. As such, it represents a useful addition to the armamentarium of the neuroendovascular specialist.

Results of the ANSWER Trial Using the PulseRider for the Treatment of Broad-Necked, Bifurcation Aneurysms

Neurosurgery ◽  
2017 ◽  
Vol 81 (1) ◽  
pp. 56-65 ◽  
Author(s):  
Alejandro M. Spiotta ◽  
Colin P. Derdeyn ◽  
Satoshi Tateshima ◽  
Jay Mocco ◽  
R. Webster Crowley ◽  
...  
Keyword(s):  
United States ◽  
Clinical Trial ◽  
The United States ◽  
Neck Size ◽  
Aneurysm Embolization ◽  
Wide Neck

Abstract BACKGROUND: The safety and probable benefit of the PulseRider (Pulsar Vascular, Los Gatos, California) for the treatment of broad-necked, bifurcation aneurysms was studied in the context of the prospective, nonrandomized, single arm clinical trial—the Adjunctive Neurovascular Support of Wide-neck aneurysm Embolization and Reconstruction (ANSWER) Trial. OBJECTIVE: To present the results of the United States cases employing the PulseRider device as part of the ANSWER clinical trial. METHODS: Aneurysms treated with the PulseRider device among sites enrolling in the ANSWER trial were prospectively studied and the results are summarized. Aneurysms arising at either the carotid terminus or basilar apex that were relatively broad necked were considered candidates for inclusion into the ANSWER study. RESULTS: Thirty-four patients were enrolled (29 female and 5 male) with a mean age of 60.9 years (27 basilar apex and 7 carotid terminus). Mean aneurysm height ranged from 2.4 to 15.9 mm with a mean neck size of 5.2 mm (range 2.3-11.6 mm). In all patients, the device was delivered and deployed. Immediate Raymond I or II occlusion was achieved in 82.4% and progressed to 87.9% at 6-month follow-up. A modified Rankin Score of 2 or less was seen in 94% of patients at 6 months. CONCLUSION: The results from the ANSWER trial demonstrate that the PulseRider device is safe and offers probable benefit as for the treatment of bifurcation aneurysms arising at the basilar apex or carotid terminus. As such, it represents a useful addition to the armamentarium of the neuroendovascular specialist.

Aphomia gularis (Zeller) (Lepidoptera, Pyralidae) at Baie d'Urfé, Quebec

1955 ◽  
Vol 87 (6) ◽  
pp. 239-240 ◽  
Author(s):  
P. H. H. Gray
Keyword(s):  
United States ◽  
The United States ◽  
United States Department ◽  
National Museum ◽  
San Jose ◽  
Department Of Agriculture ◽  
States Department ◽  
Lepidoptera Pyralidae ◽  
The U.S

This moth was first reported on this continent as a pest in a consignment of peanuts, received in California from China (de Ong, 1919). Mr. Hahn W. Capps, of the United States Department of Agriculture, informs me, in litt., that 6 adults from that infestation, together with 2 from “near prunes” in 1930, and 8 from a prune warehouse in 1931, at San José, are in the U.S. National Museum.

scholarly journals Occurrence of Ergot (Sugary Disease) Incited by a Sphacelia sp. on Sorghum in Mississippi in 1997

Plant Disease ◽  
1998 ◽  
Vol 82 (5) ◽  
pp. 590-590 ◽  
Author(s):  
N. Zummo ◽  
L. M. Gourley ◽  
L. E. Trevathan ◽  
M. S. Gonzalez ◽  
J. Dahlberg
Keyword(s):  
United States ◽  
West Africa ◽  
The United States ◽  
San Jose ◽  
Illustrated Text ◽  
Large Numbers ◽  
Claviceps Africana ◽  
Sorghum Bicolor L ◽  
Aphid Honeydew ◽  
The U.S

Ergot (sugary disease) incited by a Sphacelia sp. was observed on Sorghum bicolor (L.) Moench var. Sweet Leaf II at Leland and Pop-larville, MS, in October 1997. The disease was characterized by droplets of a thick, sticky, semi-transparent secretion similar to aphid honeydew. The caryopsis of infected florets was converted to relatively soft, chalky pink, tumescent, immature sclerotia (1.5 to 1.7 × 4 mm) with blunt ends. Abundant conidia (11 to 17 × 5 to 7 μm) were produced on stromatic tissue and in large numbers in the sugary secretion. This fungus is similar to that described by Zummo in West Africa (2). Velazquez-Valle et al. (1) recently reported the distribution of Claviceps africana Frederiksen, Mantle & de Milliano in the United States in 1997. The Sphacelia stage of the fungus found in Mississippi is similar to that reported from other areas of the U.S. Our report extends the range for this fungus, which is contiguous to those areas reported by Velazquez-Valle et al. (1). References: (1) R. Velazquez-Valle et al. 37th Annu. Mtg. Carib. Div., Am. Phytopa-thol. Soc., San Jose, Costa Rica, No. 77, 1997. (2) N. Zummo. 1984. Sorghum Diseases in West Africa. An Illustrated Text. USDA/USAID, Zaria, Nigeria.

scholarly journals Adding Person-Centered Measures to Research on Detection and Diagnosis of Dementia

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 263-263
Author(s):  
Katie Maslow
Keyword(s):  
United States ◽  
The United States ◽  
Diagnostic Evaluation ◽  
Screening Tests ◽  
Initial Screening ◽  
Diagnosis Of Dementia ◽  
Detection And Diagnosis ◽  
The U.S

Abstract In the United States, numerous studies on detection and diagnosis of dementia show that large proportions of subjects refuse initial screening tests. Moreover, among those who accept the tests, score poorly, and are therefore referred for a diagnostic evaluation, large proportions do not follow up to get the evaluation. Available data on characteristics of subjects who refuse initial screening and follow-up evaluation suggest that incorporating procedures based on person-centered concepts and practices, such as procedures that acknowledge individuals’ unique characteristics and attempt to involve, enable, and empower them, could lead to more effective detection and diagnosis. Based on results of an analysis of measures used in studies conducted in the U.S. and elsewhere, this presentation will describe frequently used measures and identify person-centered measures that could be added to studies of alternate procedures intended to increase detection and diagnosis.

scholarly journals Patient advocacy organizations’ information for patients on pre-approval access to investigational treatments

2019 ◽  
Vol 12 (1) ◽  
Author(s):  
Kelly McBride Folkers ◽  
Sarah Leone ◽  
Arthur Caplan
Keyword(s):  
United States ◽  
Clinical Trial ◽  
Clinical Trials ◽  
Drug Administration ◽  
Patient Advocacy ◽  
The United States ◽  
Patient Access ◽  
Advocacy Organizations ◽  
Lack Of Information ◽  
The U.S

Abstract Objective To evaluate the availability of information regarding patient access to investigational treatments through clinical trials and non-trial pre-approval access pathways from a sample of patient advocacy organization (PAO) websites in the United States. Results We systematically analyzed the content of 118 randomly selected PAO websites to assess whether they contained information on clinical trials and non-trial pathways—e.g., the U.S. Food and Drug Administration (FDA) expanded access (EA) program and right to try—over the course of two months from February to March 2019. A majority (81%, n = 96) of PAOs provided a link to ClinicalTrials.gov, and 73% (n = 86) had their own clinical trial finder or list of relevant trials. 23% (n = 27) mentioned EA, with 8% (n = 9) providing specific resources for FDA’s EA program. 8% (n = 10) provided a statement on the passage of the federal right to try law. A majority of PAO websites contained information on clinical trials, but a minority discussed non-trial pre-approval access. The lack of information on the latter highlights an area in need of improvement.

An American Language

2018 ◽  
Author(s):  
Rosina Lozano
Keyword(s):  
United States ◽  
National Policy ◽  
The United States ◽  
Spanish Language ◽  
Spanish Speakers ◽  
Language Recognition ◽  
Political Language ◽  
Political Issue ◽  
History Of ◽  
The U.S

An American Language is a political history of the Spanish language in the United States. The nation has always been multilingual and the Spanish language in particular has remained as an important political issue into the present. After the U.S.-Mexican War, the Spanish language became a language of politics as Spanish speakers in the U.S. Southwest used it to build territorial and state governments. In the twentieth century, Spanish became a political language where speakers and those opposed to its use clashed over what Spanish's presence in the United States meant. This book recovers this story by using evidence that includes Spanish language newspapers, letters, state and territorial session laws, and federal archives to profile the struggle and resilience of Spanish speakers who advocated for their language rights as U.S. citizens. Comparing Spanish as a language of politics and as a political language across the Southwest and noncontiguous territories provides an opportunity to measure shifts in allegiance to the nation and exposes differing forms of nationalism. Language concessions and continued use of Spanish is a measure of power. Official language recognition by federal or state officials validates Spanish speakers' claims to US citizenship. The long history of policies relating to language in the United States provides a way to measure how U.S. visions of itself have shifted due to continuous migration from Latin America. Spanish-speaking U.S. citizens are crucial arbiters of Spanish language politics and their successes have broader implications on national policy and our understanding of Americans.

Palestine Unbound

2018 ◽  
Vol 47 (3) ◽  
pp. 130-134
Keyword(s):  
United States ◽  
Human Rights ◽  
Task Force ◽  
The United States ◽  
Donald Trump ◽  
Tel Aviv ◽  
The Us ◽  
Intention To Move ◽  
Arab Israeli Conflict ◽  
The U.S

This section, updated regularly on the blog Palestine Square, covers popular conversations related to the Palestinians and the Arab-Israeli conflict during the quarter 16 November 2017 to 15 February 2018: #JerusalemIstheCapitalofPalestine went viral after U.S. president Donald Trump recognized Jerusalem as the capital of Israel and announced his intention to move the U.S. embassy there from Tel Aviv. The arrest of Palestinian teenager Ahed Tamimi for slapping an Israeli soldier also prompted a viral campaign under the hashtag #FreeAhed. A smaller campaign protested the exclusion of Palestinian human rights from the agenda of the annual Creating Change conference organized by the US-based National LGBTQ Task Force in Washington. And, UNRWA publicized its emergency funding appeal, following the decision of the United States to slash funding to the organization, with the hashtag #DignityIsPriceless.

The French Way

2011 ◽  
Author(s):  
Richard F. Kuisel
Keyword(s):  
United States ◽  
The United States ◽  
French Language ◽  
French Cinema ◽  
Free Markets ◽  
Technology Sector ◽  
Aids Epidemic ◽  
Political Reality ◽  
Politics And Culture ◽  
The U.S

There are over 1,000 McDonald's on French soil. Two Disney theme parks have opened near Paris in the last two decades. And American-inspired vocabulary such as “le weekend” has been absorbed into the French language. But as former French president Jacques Chirac put it: “The U.S. finds France unbearably pretentious. And we find the U.S. unbearably hegemonic.” Are the French fascinated or threatened by America? They Americanize yet are notorious for expressions of anti-Americanism. From McDonald's and Coca-Cola to free markets and foreign policy, this book looks closely at the conflicts and contradictions of France's relationship to American politics and culture. The book shows how the French have used America as both yardstick and foil to measure their own distinct national identity. France has charted its own path: it has welcomed America's products but rejected American policies; assailed Americ's “jungle capitalism” while liberalizing its own economy; attacked “Reaganomics” while defending French social security; and protected French cinema, television, food, and language even while ingesting American pop culture. The book examines France's role as an independent ally of the United States, but he also considers the country's failures in influencing the Reagan, Bush, and Clinton administrations. Whether investigating France's successful information technology sector or its spurning of American expertise during the AIDS epidemic, the book asks if this insistence on a French way represents a growing distance between Europe and the United States or a reaction to American globalization. Exploring cultural trends, values, public opinion, and political reality, this book delves into the complex relationship between two modern nations.

Latino Catholicism

2011 ◽  
Author(s):  
Timothy Matovina
Keyword(s):  
United States ◽  
Sixteenth Century ◽  
Catholic Church ◽  
Social Life ◽  
Social Issues ◽  
The United States ◽  
Societal Impact ◽  
Comprehensive Overview ◽  
Public Debates ◽  
The U.S

Most histories of Catholicism in the United States focus on the experience of Euro-American Catholics, whose views on social issues have dominated public debates. This book provides a comprehensive overview of the Latino Catholic experience in America from the sixteenth century to today, and offers the most in-depth examination to date of the important ways the U.S. Catholic Church, its evolving Latino majority, and American culture are mutually transforming one another. This book highlights the vital contributions of Latinos to American religious and social life, demonstrating in particular how their engagement with the U.S. cultural milieu is the most significant factor behind their ecclesial and societal impact.

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