scholarly journals Risk of Brain Arteriovenous Malformation Hemorrhage Before and After Stereotactic Radiosurgery

Stroke ◽  
2019 ◽  
Vol 50 (6) ◽  
pp. 1384-1391 ◽  
Author(s):  
Dale Ding ◽  
Ching-Jen Chen ◽  
Robert M. Starke ◽  
Hideyuki Kano ◽  
John Y.K. Lee ◽  
...  
Keyword(s):  
Arteriovenous Malformation ◽  
Stereotactic Radiosurgery ◽  
Brain Arteriovenous Malformation ◽  
Before And After

scholarly journals Expression of osteopontin, matrix metalloproteinase-2 and -9 proteins in vascular instability in brain arteriovenous malformation

PeerJ ◽  
2019 ◽  
Vol 7 ◽  
pp. e7058 ◽  
Author(s):  
Lalita Anbarasen ◽  
Jasmine Lim ◽  
Retnagowri Rajandram ◽  
Kein Seong Mun ◽  
Sheau Fung Sia
Keyword(s):  
Serum Level ◽  
Matrix Metalloproteinase ◽  
Arteriovenous Malformation ◽  
Matrix Metalloproteinase 2 ◽  
Normal Brain ◽  
Brain Arteriovenous Malformation ◽  
Serum Samples ◽  
Tissue Samples ◽  
Control Subjects ◽  
Before And After

Background Matrix metalloproteinase (MMP)-2 and -9 are Osteopontin (OPN) dependent molecules implicated in the destabilization of blood vessels. OPN and MMPs have been studied in brain arteriovenous malformation (BAVM) patients’ tissues and blood samples before intervention. In this study, we compared the serum level of these markers before and after treatment, as well as assessed their protein expressions in BAVM tissues to evaluate their roles in this disease. Methodology Serum samples from six BAVM patients and three control subjects were analyzed using enzyme-linked immunoabsorbent assay (ELISA) for OPN. A total of 10 BAVM patients and five control subjects were analyzed using Multiplex ELISA for MMPs. A total of 16 BAVM tissue samples and two normal brain tissue samples were analyzed using immunohistochemistry. Result MMP-2 and -9 were significantly higher in the serum of BAVM patients before and after treatment than in control patients. There were no significant differences of OPN and MMP-9 serum level in BAVM patients before and after treatment. MMP-2 showed a significant elevation after the treatment. Expression of OPN, MMP-2 and -9 proteins were seen in endothelial cells, perivascular cells and brain parenchyma of BAVM tissues. Conclusion Findings revealed that the level of MMP-2 and -9 in the serum correlated well with the expression in BAVM tissues in several cases. Knockdown studies will be required to determine the relationships and mechanisms of action of these markers in the near future. In addition, studies will be required to investigate the expression of these markers’ potential applications as primary medical therapy targets for BAVM patients.

scholarly journals LINAC Stereotactic Radiosurgery for brain arteriovenous malformation: a single institutional experience from Saudi Arabia

2013 ◽  
Vol 1 (1) ◽  
pp. 1 ◽  
Author(s):  
Muhammad M Fareed ◽  
Abdullah A Amro ◽  
Yasser Bayoumi ◽  
Yasser I Orz ◽  
Mutahir Tunio ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Arteriovenous Malformation ◽  
Stereotactic Radiosurgery ◽  
Brain Arteriovenous Malformation ◽  
Institutional Experience

Analysis of potential time saving in brain arteriovenous malformation stereotactic radiosurgery planning using a new software platform

2021 ◽  
Author(s):  
Guilherme Dabus ◽  
Rupesh Kotecha ◽  
Italo Linfante ◽  
D Jay Wieczorek ◽  
Alonso N Gutierrez ◽  
...  
Keyword(s):  
Arteriovenous Malformation ◽  
Stereotactic Radiosurgery ◽  
Software Platform ◽  
Brain Arteriovenous Malformation ◽  
Time Saving

De Novo Development of Moyamoya Disease after Stereotactic Radiosurgery for Brain Arteriovenous Malformation in a Patient With RNF213 p.Arg4810Lys (rs112735431)

2020 ◽  
Vol 140 ◽  
pp. 276-282
Author(s):  
Seiei Torazawa ◽  
Satoru Miyawaki ◽  
Yuki Shinya ◽  
Mariko Kawashima ◽  
Hirotaka Hasegawa ◽  
...  
Keyword(s):  
Arteriovenous Malformation ◽  
Stereotactic Radiosurgery ◽  
Moyamoya Disease ◽  
De Novo ◽  
Brain Arteriovenous Malformation

Value of cone beam computed tomography to evaluate complication of intracranial haemorrhage in endovascular treatment (evt): a case report

2019 ◽  
Vol 1 (1) ◽  
pp. 16-18 ◽  
Author(s):  
Norafida Bahari ◽  
Nik Azuan Nik Ismail ◽  
Jegan Thanabalan ◽  
Ahmad Sobri Muda
Keyword(s):  
Computed Tomography ◽  
Arteriovenous Malformation ◽  
Endovascular Treatment ◽  
Cone Beam Computed Tomography ◽  
Diagnostic Value ◽  
Cone Beam ◽  
Brain Arteriovenous Malformation ◽  
Embolic Materials

In this article, we evaluate the effectiveness of Cone Beam Computed Tomography, through a case study, in assessing the complication of intracranial bleeding during an endovascular treatment of brain arteriovenous malformation when compared to Multislice-Detector Computed Tomography performed immediately after the procedure. The image quality of Cone Beam Computed Tomography has enough diagnostic value in differentiating between haemorrhage, embolic materials and the arteriovenous malformation nidus to facilitate physicians to decide for further management of the patient.

Value of cone beam computed tomography to evaluate complication of intracranial haemorrhage in endovascular treatment (evt): a case report.

2019 ◽  
pp. 16-18
Author(s):  
Norafida Bahari ◽  
NikAzuan Nik Ismail ◽  
Jegan Thanabalan ◽  
Ahmad Sobri Muda
Keyword(s):  
Computed Tomography ◽  
Arteriovenous Malformation ◽  
Endovascular Treatment ◽  
Cone Beam Computed Tomography ◽  
Diagnostic Value ◽  
Cone Beam ◽  
Brain Arteriovenous Malformation ◽  
Embolic Materials

In this article, we evaluate the effectiveness of Cone Beam Computed Tomography, through a case study, in assessing the complication of intracranial bleeding during an endovascular treatment of brain arteriovenous malformation when compared to Multislice-Detector Computed Tomography performed immediately after the procedure. The image quality of Cone Beam Computed Tomography has enough diagnostic value in differentiating between haemorrhage, embolic materials and the arteriovenous malformation nidus to facilitate physicians to decide for further management of the patient.

scholarly journals “MEDICOLEGAL MASQUERADE” A RUPTURED BRAIN ARTERIOVENOUS MALFORMATION MIMICKING HOMICIDE: A CASE REPORT

2021 ◽  
pp. 100186
Author(s):  
Aaron Nyirenda ◽  
Cordilia Himwaze ◽  
Luchenga Mucheleng’anga
Keyword(s):  
Case Report ◽  
Arteriovenous Malformation ◽  
Brain Arteriovenous Malformation

Arterial-spin labeling MRI identifies residual cerebral arteriovenous malformation following stereotactic radiosurgery treatment

2020 ◽  
Vol 47 (1) ◽  
pp. 13-19 ◽  
Author(s):  
Jeremy J. Heit ◽  
Neil H. Thakur ◽  
Michael Iv ◽  
Nancy J. Fischbein ◽  
Max Wintermark ◽  
...  
Keyword(s):  
Arteriovenous Malformation ◽  
Stereotactic Radiosurgery ◽  
Arterial Spin Labeling ◽  
Spin Labeling ◽  
Cerebral Arteriovenous Malformation

Decision-Making in the Scheduling of Endovascular Treatment after Brain Arteriovenous Malformation Haemorrhage: A Retrospective Single Centre Study

2011 ◽  
Vol 24 (6) ◽  
pp. 879-885 ◽  
Author(s):  
J.J. Downer ◽  
M. Cellerini ◽  
R.A. Corkill ◽  
S. Lalloo ◽  
W. Küker ◽  
...  
Keyword(s):  
Early Intervention ◽  
High Risk ◽  
Arteriovenous Malformation ◽  
Endovascular Treatment ◽  
Complication Rate ◽  
Injury Severity ◽  
Endovascular Intervention ◽  
Brain Arteriovenous Malformation ◽  
Single Centre ◽  
Significant Difference

The appropriate timing for endovascular intervention after brain arteriovenous malformation (bAVM) rupture is not known. This paper aims to determine factors that lead to early endovascular intervention and to investigate whether early intervention has the same complication rate as late intervention in a single centre. All patients who underwent endovascular treatment for a ruptured bAVM at our institution in the period January 2007 and July 2010 were included in this retrospective observational study. Of 50 patients, 33 had early endovascular intervention, defined as within 30 days of haemorrhage and the remaining 17 patients had endovascular treatment at day 30 or beyond. A greater proportion of patients treated within the first 30 days were in neurointensive care preoperatively (51.5% vs. 23.5%, p=0.07). A ‘high-risk’ angioarchitectural feature was identified in more patients who had acute intervention (78.8% vs. 11.8%, p<0.0001) and targeted embolization was also more frequent in this group (48.5% vs. 5.9%, p=0.004). Nidal aneurysms, venous varices and impaired venous outflow (venous stenosis) were the principal ‘high risk’ features. Clinically apparent complications occurred in 10.8% of procedures with permanent neurological deficit in 3.6%. There was no directly procedure-related mortality. There was no statistically significant difference in the complication rate of early procedures compared with delayed interventions (12.5% vs. 7.4%, p=0.71). Greater initial injury severity and the presence of high-risk lesion characteristics are the factors that lead to early endovascular intervention. Early intervention is associated with a higher complication rate, but this difference is not statistically significant.

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