scholarly journals Mechanism of the Stratum Corneum Stripping of Acrylic Pressure Sensitive Adhesives with Different Storage Elastic Modulus

2011 ◽  
Vol 47 (12) ◽  
pp. 465-470 ◽  
Author(s):  
Kentaro MIYAZAKI ◽  
Tomoko TATSUNO ◽  
Sou MIYATA
Keyword(s):  
Elastic Modulus ◽  
Stratum Corneum ◽  
Pressure Sensitive Adhesives ◽  
Pressure Sensitive

Adhesion of Pressure Sensitive Adhesives with Applications in Transdermal Drug Delivery

2000 ◽  
Vol 662 ◽  
Author(s):  
Marc B. Taub ◽  
Reinhold H. Dauskardt
Keyword(s):  
Drug Delivery ◽  
Stratum Corneum ◽  
Large Scale ◽  
Adhesive Layer ◽  
Strain Energy Release ◽  
Work Of Adhesion ◽  
Adhesive Properties ◽  
Pressure Sensitive Adhesives ◽  
Pressure Sensitive ◽  
Beam Sample

AbstractThe development and implementation of successful transdermal devices for drug delivery requires an understanding of the adhesion occurring between the device and the soft dermal layer. This study utilizes a mechanics approach to quantify the adhesive properties of representative pressure sensitive adhesives (PSAs) used as the adhesive layer in these systems. Debonding of PSAs is accompanied by cavitation in the PSA and the formation of an extensive cohesive zone behind the debond tip. The presence of such large-scale bridging provides significant energy dissipation and increased resistance to delamination. The strain energy release rate (G) during debonding of a cantilever-beam sample, containing at its midline a thin layer of PSA, was utilized to quantify the adhesion of the PSA. The analysis accounts for both the work of adhesion as well as the viscoelastic constitutive behavior of the soft adhesive layer. Effects of strain rate, physiological environment, and permeation-enhancement additions are considered. The resistance of human stratum corneum to debonding between corneocyte layers is also presented, as knowledge of this parameter is essential for developing techniques to test the fracture resistance of the PSA-stratum corneum interface present in the clinical use of these transdermal devices.

Passivation of pressure sensitive adhesive stickies by addition of acrylic fibers to OCC pulp before papermaking

TAPPI Journal ◽  
2016 ◽  
Vol 15 (10) ◽  
pp. 631-639
Author(s):  
MOHAMMAD HADI ARYAIE MONFARED ◽  
HOSSEIN RESALATI ◽  
ALI GHASEMIAN ◽  
MARTIN A. HUBBE
Keyword(s):  
Adverse Effects ◽  
Control Sample ◽  
Pressure Sensitive Adhesive ◽  
Acrylic Fiber ◽  
Burst Strength ◽  
Pressure Sensitive Adhesives ◽  
Pressure Sensitive ◽  
Tear Index ◽  
Breaking Length ◽  
Acrylic Fibers

This study investigated the addition of acrylic fiber to old corrugated container (OCC) pulp as a possible means of overcoming adverse effects of water-based pressure sensitive adhesives during manufacture of paper or paperboard. Such adhesives can constitute a main source of stickies, which hurt the efficiency of the papermaking process and make tacky spots in the product. The highest amount of acrylic fiber added to recycled pulps generally resulted in a 77% reduction in accepted pulp microstickies. The addition of acrylic fibers also increased pulp freeness, tear index, burst strength, and breaking length, though there was a reduction in screen yield. Hence, in addition to controlling the adverse effects of stickies, the addition of acrylic fibers resulted in the improvement of the mechanical properties of paper compared with a control sample.

Aspects of Pressure Sensitive Adhesives in Fabricating Drug-in-Adhesive Transdermal Therapeutic Systems

2017 ◽  
Vol 7 (1) ◽  
pp. 3-15 ◽  
Author(s):  
Anurag Verma ◽  
Vaibhav Rastogi ◽  
Pragya Yadav ◽  
Niharika Lal
Keyword(s):  
Pressure Sensitive Adhesives ◽  
Pressure Sensitive

Biobased acrylic pressure-sensitive adhesives

2021 ◽  
Vol 117 ◽  
pp. 101396
Author(s):  
Martijn A. Droesbeke ◽  
Resat Aksakal ◽  
Alexandre Simula ◽  
José M. Asua ◽  
Filip E. Du Prez
Keyword(s):  
Pressure Sensitive Adhesives ◽  
Pressure Sensitive
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