Alpha-Glucosidase Inhibitor Activity of Momordica Charantia L After Inoculated by Endophytic Bacteria

2017 ◽  
Vol 23 (7) ◽  
pp. 6490-6492
Author(s):  
Sri Pujiyanto ◽  
Sunarno ◽  
Rejeki Siti Ferniah
Keyword(s):  
Endophytic Bacteria ◽  
Momordica Charantia ◽  
Inhibitor Activity ◽  
Glucosidase Inhibitor ◽  
Alpha Glucosidase

Produksi Dan Ekstraksi Inhibitor Alfa Glukosidase Dari Isolat Aktinomiset Jp-3

2016 ◽  
Vol 17 (2) ◽  
pp. 123
Author(s):  
Sri Pujiyanto ◽  
Rejeki Siti Ferniah ◽  
Sunarno S
Keyword(s):  
Ethyl Acetate ◽  
Active Compound ◽  
Inhibitor Activity ◽  
Glucosidase Inhibitor ◽  
Glucosidase Inhibitors ◽  
Complex Carbohydrates ◽  
Diabetes Drug ◽  
Chloroform Methanol ◽  
Alpha Glucosidase

Alpha-glucosidase inhibitors are compounds that can prevent the digestion of complex carbohydrates into glucose, so potentially used as a diabetes drug. This study aims to examine the production and extraction of alpha-glucosidase inhibitor compound from Isolate Aktinomiset JP-3 from the sea. The supernatant obtained from the culture of the JP-3 isolate was extracted using various solvents to obtain the active compound. The solvents used were chloroform, methanol, and ethyl acetate. An assay of inhibitor activity of the α-glucosidase using p-nitrophenyl α-D-glucopyranoside substrate. The activity of the enzyme is measured based on the absorbance of p-nitrophenol produced from the breaking reaction of the substrate. The results showed that extraction of alpha-glucosidase inhibitor compound with ethyl acetate yielded extract with highest inhibitor activity. Keywords: alpha-glucosidase inhibitors, actinomycetes, diabetes, extraction, fractionation

scholarly journals At A Glance On Kothala himbutu

2019 ◽  
Vol 4 (3) ◽  
Keyword(s):  
Insulin Resistance ◽  
Medicinal Plant ◽  
Hormone Sensitive Lipase ◽  
Ayurvedic Medicine ◽  
Inhibitor Activity ◽  
Glucosidase Inhibitor ◽  
Hormone Sensitive ◽  
Reduce Insulin Resistance ◽  
Diabetes And Obesity ◽  
Alpha Glucosidase

Kothala himbutu (Salacia reticulate; SR) is a very useful medicinal plant in Sri Lanka and the southern region of India. SR contains salacinol and kotalanol neosalacinol and neokotalanol which can isolated from the Salacia species by using iron pair chromatography [1& 2]. It is a woody climber and widely used in Ayurvedic medicine for diabetes and obesity treatment. Previously, the action of SR for diabetes is not described properly. Researchers tried to explore the effect of SR and found that it has an alpha glucosidase inhibitor activity in invitro study. Moreover, SR may increase lipolysis and reduce insulin resistance by enhancing mRNA expression for hormone sensitive lipase (HSL) and adiponectin [3].

P1-25 THE ALPHA-GLUCOSIDASE INHIBITOR VOGLIBOSE REDUCES MYOCARDIAL INFARCT SIZE TROUGH PRODUCTION OF GLUCAGON-LIKE PEPTIDE-1 IN RABBITS

2007 ◽  
Vol 122 ◽  
pp. S68
Author(s):  
Masamitsu Iwasa ◽  
Hiroyuki Kobayashi ◽  
Shinji Yasuda ◽  
Narentuoya Bao Itta Kawamura ◽  
Takahiko Yamaki ◽  
...  
Keyword(s):  
Infarct Size ◽  
Myocardial Infarct ◽  
Myocardial Infarct Size ◽  
Glucosidase Inhibitor ◽  
Glucagon Like Peptide ◽  
Glucagon Like Peptide 1 ◽  
Alpha Glucosidase

scholarly journals IN VITRO EFFECT OF TERPENOIDS - RICH EXTRACT OF Momordica charantia ON ALPHA GLUCOSIDASE ACTIVITY

Revista Vitae ◽  
2018 ◽  
Vol 25 (3) ◽  
pp. 148-153 ◽  
Author(s):  
A. B. Sallau ◽  
◽  
R. N. Yakubu ◽  
S. M. Aliyu ◽  
A. Salihu ◽  
...  
Keyword(s):  
Momordica Charantia ◽  
Glucosidase Activity ◽  
Vitro Effect ◽  
Alpha Glucosidase

scholarly journals α-Amylase inhibitor activity of endophytic bacteria isolated from Annona muricata L

2018 ◽  
Vol 1025 ◽  
pp. 012085
Author(s):  
Sri Pujiyanto ◽  
Merysa Resdiani ◽  
Budi Raharja ◽  
Rejeki Siti Ferniah
Keyword(s):  
Endophytic Bacteria ◽  
Annona Muricata ◽  
Inhibitor Activity ◽  
Amylase Inhibitor

Long-term effect of alpha-glucosidase inhibitor on late dumping syndrome

1998 ◽  
Vol 13 (12) ◽  
pp. 1201-1206 ◽  
Author(s):  
TAKENAO HASEGAWA ◽  
MASASHI YONEDA ◽  
KIMIHIDE NAKAMURA ◽  
KUNIYO OHNISHI ◽  
HIROYUKI HARADA ◽  
...  
Keyword(s):  
Term Effect ◽  
Dumping Syndrome ◽  
Glucosidase Inhibitor ◽  
Long Term Effect ◽  
Late Dumping Syndrome ◽  
Alpha Glucosidase

scholarly journals Iminosugars With Endoplasmic Reticulum α-Glucosidase Inhibitor Activity Inhibit ZIKV Replication and Reverse Cytopathogenicity in vitro

2020 ◽  
Vol 11 ◽  
Author(s):  
Gitanjali Bhushan ◽  
Levina Lim ◽  
Ian Bird ◽  
Shubhada K. Chothe ◽  
Ruth H. Nissly ◽  
...  
Keyword(s):  
Endoplasmic Reticulum ◽  
Inhibitor Activity ◽  
Glucosidase Inhibitor
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