Carbon Dots from Guar Gum: Synthesis, Characterization and Preliminary Study of Carbon Dots Penetration into Spinacia oleracea Leaf Cells

2018 ◽  
Vol 12 (6) ◽  
pp. 764-771
Author(s):  
S.K. Bajpai ◽  
A. D'souza ◽  
Basharat Suhail
Keyword(s):  
Carbon Dots ◽  
Guar Gum ◽  
Spinacia Oleracea ◽  
Preliminary Study

scholarly journals In Vivo Ciprofloxacin Release from Hydroxyapatite-Based Bone Implants in Rabbit Tibia: A Preliminary Study

2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Amit Kumar Nayak ◽  
Ajoy Bhattacharyya ◽  
Kalyan Kumar Sen
Keyword(s):  
Guar Gum ◽  
Preliminary Investigation ◽  
Hplc Method ◽  
Preliminary Evaluation ◽  
Bone Implants ◽  
Rabbit Tibia ◽  
Preliminary Study ◽  
The Right ◽  
Local Antibiotic

The present study deals with the preliminary evaluation of in vivo ciprofloxacin release from HAp-ciprofloxacin bone implants in rabbit tibia. The HAp-ciprofloxacin implants ( mm) were prepared using various HAp-ciprofloxacin composites synthesized by precipitation technique and 1.5% w/v guar gum as a binder. 5 implants were implanted in artificial cortical bone window at the right proximal tibia of each rabbit. After 3- and 6-day intervals, the rabbits were euthanized. Bone marrow and serum concentrations of ciprofloxacin were determined from the harvested tibia using HPLC method. The results displayed the availability of elevated local antibiotic concentration at the implanted site with the limitation of systemic antibiotic exposure, which can be useful to minimize the risk of systemic toxicity-related side effects. This study is the preliminary investigation of the suitability of in vivo ciprofloxacin release from HAp-ciprofloxacin bone implants in rabbit tibia, after implantation, and these implants can be useful for the treatment of bacterial bone infections like osteomyelitis.

Green synthesis of Zingiberis rhizoma-based carbon dots attenuates chemical and thermal stimulus pain in mice

Nanomedicine ◽  
2020 ◽  
Vol 15 (9) ◽  
pp. 851-869
Author(s):  
Meiling Zhang ◽  
Jinjun Cheng ◽  
Yue Zhang ◽  
Hui Kong ◽  
Suna Wang ◽  
...  
Keyword(s):  
Analgesic Activity ◽  
Carbon Dots ◽  
Functional Group ◽  
Biomedical Application ◽  
Chemical Stimulus ◽  
Thermal Stimulus ◽  
Hot Plate ◽  
Pyrolysis Method ◽  
Tail Immersion ◽  
Preliminary Study

Aim: To evaluate the analgesic activity of Zingiberis rhizoma-based carbon dots (ZR-CDs). Materials & methods: Novel ZR-CDs were prepared via a facile, green pyrolysis method. Microstructure, optical and functional group properties were characterized. Acetic acid writhing, hot-plate and tail-immersion tests were performed using mice to evaluate the analgesic activity of ZR-CDs, followed by a preliminary study on the analgesic mechanism. Results: ZR-CDs with a quantum yield of 5.2% had a diameter ranging from 2.23 to 3.77 nm. Remarkable analgesic effect of ZR-CDs was observed against both thermal and chemical stimulus tests, possibly mediated by an opioid-like mechanism and the regulation of 5-hydroxytryptamine levels. Conclusion: ZR-CDs have a promising potential for biomedical application in relieving pain-related diseases.

Effect of guar gum on nitrogen secretion into isolated loops of jejunum in conscious growing pigs

1984 ◽  
Vol 52 (3) ◽  
pp. 499-505 ◽  
Author(s):  
A. G. Low ◽  
Anna L. Rainbird
Keyword(s):  
Protein Synthesis ◽  
Small Intestine ◽  
Dietary Fibre ◽  
Guar Gum ◽  
Live Weight ◽  
Growing Pigs ◽  
N Metabolism ◽  
Preliminary Study ◽  
Nitrogen Secretion

1. Four pigs, initially of 30 kg live weight, were surgically prepared with two re-entrant cannulas in the jejunum, 1.0 m apart. This allowed an isolated loop to be formed through which Ringer solutions were continuously perfused for 6.5-h periods per day.2. The effects of two Ringer solutions of contrasting composition on nitrogen secretion were measured in a preliminary study.3. The effects of guar gum (6.7 g/l) on N secretion during perfusions of solutions of glucose or of maltose (20 g/l) were measured.4. N secretion did not differ significantly between the two Ringer solutions.5. Addition of guar gum to the solution of glucose increased mean N secretion from 69.2 to 133.9 mg/m per 2 h; the corresponding values for the maltose solution were 75.5 and 120.2 mg/m per 2 h. In both cases the differences were significant (P< 0.001). Differences between N secretion into glucose and maltose solutions were not significant, either without or with guar gum.6. Guar gum addition had a greater effect on N secretion in hours 5 and 6 than in hours 1 and 2 of perfusion.7. It was calculated that guar gum would have increased N secretion by the mucosa of the whole small intestine from approximately 15 to 27 g/d under the conditions of the study, assuming uniform secretion throughout the organ. These results suggest that certain types of dietary fibre may be important determinants of N secretion by the mucosa of the small intestine. They also suggest that changes in N secretion of this magnitude are of importance in N metabolism because the overall rate of protein synthesis in these pigs was probably about 100 g/d (expressed as N), using values from the literature.

scholarly journals Spinach Tissue Culture Improved with Coconut Water

HortScience ◽  
1992 ◽  
Vol 27 (4) ◽  
pp. 357-358 ◽  
Author(s):  
Jameel M. Al-Khayri ◽  
Feng H. Huang ◽  
Teddy E. Morelock ◽  
Tahani A. Busharar
Keyword(s):  
Shoot Regeneration ◽  
Culture Medium ◽  
Shoot Growth ◽  
Spinacia Oleracea ◽  
Coconut Water ◽  
Free Medium ◽  
Regeneration Medium ◽  
Regeneration Frequency ◽  
Regenerative Capacity ◽  
Preliminary Study

A preliminary study has shown that the addition of 15% (v/v) coconut water (CW) to the culture medium significantly improved callus growth, shoot-regenerative capacity, and shoot growth in leaf disk cultures of spinach (Spinacia oleracea L.). Subsequently, the influence of a range of CW concentrations, 0%, 5%, 10%, 15%, or 20% (v/v), was examined. Callus weight obtained after 5 weeks showed direct relationship to the concentration of CW. This stimulator action was observed in both cultivars tested in this study, `High Pack' and `Baker'. On CW-containing medium, shoot regeneration was expedited to 4 to 5 weeks compared with 8 to 12 weeks on a CW-free medium. Callus of `Baker' induced on a CW-free medium exhibited a significant increase in shoot regeneration frequency when transferred to a regeneration medium enriched with CW, suggesting that the addition of CW to the regeneration medium only is sufficient to achieve improved regeneration.

The Ultrastructure of Metastatic Human Mammary Carcinoma After Prolonged Estrogen Therapy

1967 ◽  
Vol 25 ◽  
pp. 180-181
Author(s):  
John H.L. Watson ◽  
John L. Swedo ◽  
R.W. Talley
Keyword(s):  
Mammary Carcinoma ◽  
Osmium Tetroxide ◽  
Estrogen Therapy ◽  
Ultrastructural Level ◽  
Uranyl Acetate ◽  
Human Mammary Carcinoma ◽  
Surgical Biopsy ◽  
Lead Hydroxide ◽  
Preliminary Study ◽  
Hormonal Therapies

A preliminary study of human mammary carcinoma on the ultrastructural level is reported for a metastatic, subcutaneous nodule, obtained as a surgical biopsy. The patient's tumor had responded favorably to a series of hormonal therapies, including androgens, estrogens, progestins, and corticoids for recurring nodules over eight years. The pertinent nodule was removed from the region of the gluteal maximus, two weeks following stilbestrol therapy. It was about 1.5 cms in diameter, and was located within the dermis. Pieces from it were fixed immediately in cold fixatives: phosphate buffered osmium tetroxide, glutaraldehyde, and paraformaldehyde. Embedment in each case was in Vestopal W. Contrasting was done with combinations of uranyl acetate and lead hydroxide.

Fine structure of early degenerating myofibers in the tibialis anterior of young ‘MDX’ mouse

1988 ◽  
Vol 46 ◽  
pp. 322-323
Author(s):  
H.D. Geissinger ◽  
C.K. McDonald-Taylor
Keyword(s):  
Fine Structure ◽  
Muscle Regeneration ◽  
Tibialis Anterior ◽  
Genetic Defect ◽  
Mdx Mouse ◽  
Mdx Mice ◽  
Histopathological Changes ◽  
Electron Microscopic ◽  
Dystrophic Mouse ◽  
Preliminary Study

A new strain of mice, which had arisen by mutation from a dystrophic mouse colony was designated ‘mdx’, because the genetic defect, which manifests itself in brief periods of muscle destruction followed by episodes of muscle regeneration appears to be X-linked. Further studies of histopathological changes in muscle from ‘mdx’ mice at the light microscopic or electron microscopic levels have been published, but only one preliminary study has been on the tibialis anterior (TA) of ‘mdx’ mice less than four weeks old. Lesions in the ‘mdx’ mice vary between different muscles, and centronucleation of fibers in all muscles studied so far appears to be especially prominent in older mice. Lesions in young ‘mdx’ mice have not been studied extensively, and the results appear to be at variance with one another. The degenerative and regenerative aspects of the lesions in the TA of 23 to 26-day-old ‘mdx’ mice appear to vary quantitatively.

Ultrastructural observations of the aorta of calves implanted with a mechanical left ventricular assist device

1990 ◽  
Vol 48 (3) ◽  
pp. 834-835
Author(s):  
J P Cassella ◽  
V Salih ◽  
T R Graham
Keyword(s):  
Left Ventricular Assist Device ◽  
Ventricular Assist Device ◽  
Left Ventricular ◽  
Aortic Tissue ◽  
Assist Device ◽  
Ventricular Assist ◽  
Transmission Electron ◽  
Left Ventricular Assist ◽  
Preliminary Study

Left ventricular assist systems are being developed for eventual long term or permanent implantation as an alternative to heart transplantation in patients unsuitable for or denied the transplant option. Evaluation of the effects of these devices upon normal physiology is required. A preliminary study was conducted to evaluate the morphology of aortic tissue from calves implanted with a pneumatic Left Ventricular Assist device-LVAD. Two 3 month old heifer calves (calf 1 and calf 2) were electively explanted after 128 days and 47 days respectively. Descending thoracic aortic tissue from both animals was removed immediately post mortem and placed into karnovsky’s fixative. The tissue was subsequently processed for transmission electron microscopy (TEM). Some aortic tissue was fixed in neutral buffered formalin and processed for routine light microscopy.

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