Analysis of Clinical Features, Pathological Features and Misdiagnosis of Pulmonary Lymphoma

Primary pulmonary lymphoma is a relatively rare extranodal lymphoma, and the incidence rate has increased in recent years. In the past, the disease mainly relied on surgery to obtain the pathological basis, so the clinical misdiagnosis rate was high. How to improve its early diagnosis and treatment has attracted much attention. By exploring the imaging manifestations of primary pulmonary lymphoma, we can further understand and improve the imaging diagnosis level of primary pulmonary lymphoma. This paper discusses the classification, imaging manifestations, diagnosis and identification of pulmonary lymphoma. The clinical data and imaging findings of primary pulmonary lymphoma diagnosed in a hospital were retrospectively summarized, and their imaging features were analyzed. We observe the clinicopathological characteristics and immunohistochemical phenotypes of multiple masses with cavitation type primary lung lymphoma, and analyze the virus and imaging characteristics of hybridization. The results of the study show that the CT (Computed Tomography) manifestations of primary lung lymphoma are diverse. The characteristics of cross-leaf distribution are more characteristic, and enhanced scanning lesions are usually mild to moderate. In the case of simultaneous masses and pneumonialike consolidation in the lungs, this disease needs to be considered.

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Imaging diagnosis of classical and new pneumoconiosis: predominant reticular HRCT pattern

Insights into Imaging ◽

10.1186/s13244-021-00966-y ◽

2021 ◽

Vol 12 (1) ◽

Author(s):

Akira Masanori

Keyword(s):

Computed Tomography ◽

Interstitial Lung Disease ◽

Imaging Features ◽

Imaging Findings ◽

Imaging Diagnosis ◽

High Resolution Computed Tomography ◽

Pleural Fibrosis ◽

Pathologic Findings ◽

Characteristic Imaging ◽

The Individual

AbstractOur understanding of the manifestations of pneumoconioses is evolving in recent years. Associations between novel exposures and diffuse interstitial lung disease have been newly recognized. In advanced asbestosis, two types of fibrosis are seen, probably related to dose of exposure, existence of pleural fibrosis, and the host factor status of the individual. In pneumoconiosis of predominant reticular type, nodular opacities are often seen in the early phase. The nodular pattern is centrilobular, although some in metal lung show perilymphatic distribution, mimicking sarcoidosis. High-resolution computed tomography enables a more comprehensive correlation between the pathologic findings and clinically relevant imaging findings. The clinician must understand the spectrum of characteristic imaging features related to both known dust exposures and to historically recent new dust exposures.

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Clinicopathological characteristics and prognostic factors of primary pulmonary lymphoma

Journal of Thoracic Disease ◽

10.21037/jtd-20-3159 ◽

2021 ◽

Vol 13 (2) ◽

pp. 1106-1117

Author(s):

Huayu He ◽

Fengwei Tan ◽

Qi Xue ◽

Lei Liu ◽

Yue Peng ◽

...

Keyword(s):

Prognostic Factors ◽

Clinicopathological Characteristics ◽

Primary Pulmonary Lymphoma ◽

Pulmonary Lymphoma

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Imaging Features of Intracranial Meningiomas with Histopathological Correlation: A Relook into Old Disease

Nepalese Journal of Radiology ◽

10.3126/njr.v3i1.8713 ◽

2013 ◽

Vol 3 (1) ◽

pp. 14-32

Author(s):

K Gangadhar ◽

D Santhosh ◽

GM Fatterpekar

Keyword(s):

Mr Imaging ◽

Signs And Symptoms ◽

Intracranial Meningioma ◽

Imaging Features ◽

Imaging Findings ◽

Histopathological Correlation ◽

Imaging Characteristics ◽

Dural Tail ◽

Atypical Meningiomas ◽

Weighted Sequences

Background and Purpose: Imaging characteristics of meningiomas have been discussed previously in many studies; however complete imaging features involving general features, MRS and DWI of both typical and atypical meningiomas have been discussed in very few studies. CT and MR imaging findings in 46 cases of intracranial meningioma are reviewed to define specific imaging features. Methods: The present study was carried on 46 patients in the Department of Radiodiagnosis and Imaging, Institute of Medical Sciences, Banaras Hindu University during June 2009 to July 2011.The investigation was carried out by GE-VCT 64 Slice Scanner machine and Magnetic resonance imaging was contemplated using 1.5 Tesla SIEMENS-MAGNETOM AVANTO. CT and MR imaging studies were reviewed to characterize mass location, imaging characteristics, atypical features and advanced imaging features. Clinical presenting signs and symptoms were correlated with imaging findings. Results: a). Forty six cases of intra cranial meningiomas were studied prospectively in 24 women and 22men, aged 11 – 80 years. Meningiomas were stratified into typical and atypical and also depending upon intra cranial location. b). 73.91% of the cases in showed supratentorial location, rest were infratentorial (26.08%).CT/MRI revealed well defined margins in 84.78% with homogenous consistency in 73.91% of lesions. Foci of necrosis were noted in 32.60% of cases and 15.22% of cases showed calcification foci in meningioma. Sinus invasion noticed in 15.22% of cases, whereas adjacent bony reaction noticed in 30.43% of cases. c). Majority of Meningioma showed broad dural base (89.10%), adjacent white matter buckling (71.74%) and surrounding CSF cleft (52.17%). Displaced subarachnoid vessels were demonstrated in 30.43%, where as the pathognomonic dural tail was present in only 23.91% of the cases. d). All the cases of Meningioma demonstrated restriction on diffusion weighted sequences suggestive of high cellularity of the lesions. On CT angiography, neovascularity was noticed in 85.71% and tumor blush was noticed in 71.42% incidence. On MR Spectroscopy, all demonstrated choline peak and in one third cases alanine peak was discernible. Conclusion: In view of the observed evidence, it was concluded that understanding the classification, pathology and imaging appearance meningioma are essential for treatment planning. CT and MR imaging play indispensable role in the localization & characterization of these tumors, and MR have virtually yielded its position of dominance in characterizing these tumors. Nepalese Journal of Radiology / Vol.3 / No.1 / Issue 4 / Jan-June, 2013 / 14-32 DOI: http://dx.doi.org/10.3126/njr.v3i1.8713

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Peripheral Seronegative Spondyloarthritis – Updates on Critical Criteria

10.25259/ijmsr_36_2019 ◽

2019 ◽

Vol 1 ◽

pp. 101-107

Author(s):

Amit Shah ◽

Kethesparan Paramesparan ◽

Winston J. Rennie

Keyword(s):

Diagnostic Delay ◽

Treatment Delay ◽

Referral Source ◽

Imaging Features ◽

Imaging Findings ◽

The Past ◽

Pictorial Review ◽

Patient Morbidity ◽

Specialist Referral ◽

Seronegative Spondyloarthritis

In the past decade, new clinical and imaging criteria have vastly improved the diagnosis and outcome of patients with seronegative spondyloarthritis (SpA). It is estimated that up to 30% of patients with SpA may exhibit predominant (or only) peripheral manifestations of SpA. Lack of awareness can lead to a diagnostic delay of up to 8–9 years which can lead to significant patient morbidity. It is, therefore, essential to diagnose and treat SpA as early as possible. The aim of this pictorial review is to emphasize the important aspects of current peripheral SpA classification system and demonstrates the imaging findings related to peripheral SpA. Patients referred for imaging of peripheral joints can be from a wide referral source. Recognizing and reporting imaging features suggestive of peripheral SpA will allow appropriate and timely specialist referral with the aim of avoiding treatment delay.

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Comparison of ultrasound and Contrast- enhanced computed tomography in clinically diagnosed cases of acute pancreatitis

Journal of Patan Academy of Health Sciences ◽

10.3126/jpahs.v8i1.36864 ◽

2021 ◽

Vol 8 (1) ◽

pp. 51-57

Author(s):

Pooja Jaiswal ◽

Shreejana Shrestha ◽

Yogita Dwa

Keyword(s):

Acute Pancreatitis ◽

Diagnostic Accuracy ◽

Standard Technique ◽

Dynamic Imaging ◽

Radiology Department ◽

Imaging Features ◽

Imaging Findings ◽

Imaging Characteristics ◽

Contrast Enhanced Ct ◽

Contrast Enhanced

Introduction: Acute pancreatitis (AP) is an acute, mainly diffuse, inflammatory process of the pancreas with dynamic imaging characteristics and a multitude of possible complications. Imaging plays an important role in the diagnosis of AP. As most of the AP cases are gallstone-related, ultrasound (USG) is the most common initial radiologic investigation of choice. Contrast-enhanced CT (CECT) is the standard technique for overall assessment of AP and its complications. This study aims to compare diagnostic accuracy of imaging findings of USG with CECT. Method: This was a retrospective review of imaging findings of USG and CECT in clinically diagnosed cases of AP who visited Radiology Department of Patan Hospital, Patan Academy of Health Sciences, Kathmandu, Nepal during 2015 to 2019 and had undergone USG and CECT. The diagnostic accuracy of USG and CECT imaging findings were compared. Study was approved ethically. Result: Among 210 clinically diagnosed cases of acute pancreatitis, USG accurately diagnosed 97(46.2%), CECT 180(85.7%). Both the modalities detected cholelithiasis in 17% of the cases. Out of 97 cases, 85 showed focal or diffuse enlargement of pancreas on USG. Conclusion: The CECT showed higher diagnostic accuracy for acute pancreatitis as compared to ultrasound, 85.7% vs. 46.2%. The overall visualization of the imaging features of AP and its complications was better by CECT than by USG.

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Multinodular/plexiform (multifascicular) schwannomas of major peripheral nerves: an underrecognized part of the spectrum of schwannomas

Journal of Neurosurgery ◽

10.3171/2009.5.jns09244 ◽

2010 ◽

Vol 112 (2) ◽

pp. 372-382 ◽

Cited By ~ 26

Author(s):

Marie-Noëlle Hébert-Blouin ◽

Kimberly K. Amrami ◽

Bernd W. Scheithauer ◽

Robert J. Spinner

Keyword(s):

Peripheral Nerves ◽

Clinical Presentation ◽

Imaging Features ◽

Surgical Results ◽

Nerve Sheath Tumors ◽

The Past ◽

Nerve Sheath ◽

Imaging Characteristics ◽

Complex Forms ◽

Distinguishing Features

Object In clinical practice, schwannomas are among the most common types of nerve sheath tumors. Their clinical presentation, imaging characteristics, and operative features are well known. Over the past 20 years, clinical outcomes have improved due to resection of these tumors at a fascicular level. Despite these advances, a subgroup of patients with schwannomas is associated with a disappointing neurological outcome following resection. The purpose of this study was to correlate the imaging and histological features in this group of patients with more anatomically complex forms of schwannomas. Methods In a retrospective review performed at their institution over a 10-year period, the authors found a subgroup of patients with complex multinodular/plexiform schwannomas affecting major peripheral nerves. Eleven patients were identified, and the clinical, imaging, and pathological features of their disease were reviewed. Results The clinical presentation of multinodular/plexiform schwannomas of major peripheral nerves may be similar to that of conventional schwannomas, but their imaging features, operative appearance, and outcomes differ. Conclusions Preoperatively and intraoperatively, the distinguishing features of multinodular/plexiform schwannomas of major peripheral nerves may be subtle and can easily go unrecognized, thus explaining the often suboptimal surgical results. Familiarity with the imaging and operative features of multinodular/plexiform schwannomas will no doubt alter treatment approaches and improve neurological function in this subgroup of patients.

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A Retrospective Study on Clinical Significance of Imaging And Endobronchial Features In Pulmonary Lymphoma Diagnosed By Bronchoscopy: When Should We Perform Bronchoscopy?

10.21203/rs.3.rs-439281/v1 ◽

2021 ◽

Author(s):

Shao-Ting Wang

Keyword(s):

B Cell Lymphoma ◽

Standard Uptake Value ◽

Diagnostic Value ◽

Imaging Features ◽

Accurate Analysis ◽

Large B Cell Lymphoma ◽

Biopsy Specimens ◽

Primary Pulmonary Lymphoma ◽

Pulmonary Lymphoma ◽

The Common

Abstract Background: Pulmonary lymphoma is rare while the radiographic lesions are nonspecific. The use of bronchoscopy, is controversial, and may be of limited diagnostic value for pulmonary lymphoma diagnosis.Methods: Cases of pulmonary lymphoma diagnosed by bronchoscopy were retrospectively reviewed from January 2010 till December 2020. Clinico-radiological records of these cases were retrieved and bronchoscopy was performed with histopathological evaluation of the biopsy specimens. Results: Of the 41 cases included in our study, 20 were primary pulmonary lymphoma. The majority of subtypes were diffuse large B-cell lymphoma(43.9%) and extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue lymphoma(29.3%), with high percentage of underlying chronic disease. The common Computed Tomography(CT) abnormalities were mass(43.9%), consolidation(24.4%) or ground-glass opacities(24.4%). To evaluate the pulmonary lesions distribution, 41.5% patients had segmental lesions, 29.3% presences of diffuse lesions, 17.1% of local lesions and 12.2% of hilar lesions, with the maximal value of standard uptake value (SUVmax) median value of 9.6. At bronchoscopy, 41.5% lesions were identified as focal solitary mass, 22% were normal, 17.1% were mucosae asperity or edema, 9.8% were diffuse airway submucosal nodules or thickening and 9.8% were bronchiole stenosis, while certain endobronchial patterns may correspond to specific imaging features. Conclusion: The imaging features and endobronchial patterns of pulmonary lymphoma are characteristic. Bronchoscopy is still a useful tool, that is minimally invasive, to diagnose pulmonary lymphoma, while accurate analysis of the clinico-radiological records is essential before such procedure.

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Imaging diagnosis of autoimmune pancreatitis: computed tomography and magnetic resonance imaging

Journal of Medical Ultrasonics ◽

10.1007/s10396-021-01145-8 ◽

2021 ◽

Author(s):

Hiroshi Ogawa ◽

Yasuo Takehara ◽

Shinji Naganawa

Keyword(s):

Autoimmune Pancreatitis ◽

Systemic Disease ◽

Imaging Features ◽

Resonance Imaging ◽

Imaging Diagnosis ◽

Contrast Administration ◽

Quarter Century ◽

The Past ◽

Characteristic Imaging ◽

Ct And Mri

AbstractAutoimmune pancreatitis (AIP) is a pancreatic phenotype of IgG4-related systemic disease. Since its first description in the literature, characteristic imaging features have gradually become known to many clinicians encompassing various specialties in the past quarter century. CT and MRI have been the workhorses for imaging diagnosis of AIP. Typical features include sausage-like swelling of the focal or entire pancreas, duct-penetrating sign, a capsule-like rim of the affected lesions, and homogeneous delayed enhancement or enhanced duct sign after contrast administration, as well as characteristic combined findings reflecting coexisting pathologies in the other organs as a systemic disease. In this review, recent and future developments in CT and MRI that may help diagnose AIP are discussed, including restricted diffusion and perfusion and increased elasticity measured using MR.

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