Clozapine-Loaded Polysorbate-Coated Polymeric Nanocapsules: Physico-Chemical Characterization and Toxicity Evaluation in Caenorhabditis elegans Model

2016 ◽  
Vol 16 (2) ◽  
pp. 1257-1264 ◽  
Author(s):  
Barbra Katyúscya Sanches Moraes ◽  
Simone Machado Vieira ◽  
Willian Goulart Salgueiro ◽  
Luana Roberta Michels ◽  
Letícia Marques Colomé ◽  
...  
Keyword(s):  
Caenorhabditis Elegans ◽  
Chemical Characterization ◽  
Toxicity Evaluation ◽  
Physico Chemical ◽  
Polymeric Nanocapsules

Physico-chemical characterization and aging effects of fructan exopolysaccharide produced by Weissella cibaria MD2 on Caenorhabditis elegans

LWT ◽  
2021 ◽  
Vol 143 ◽  
pp. 111100
Author(s):  
Avinash Kant Lakra ◽  
Mahesh Ramatchandirane ◽  
Sandeep Kumar ◽  
Kitlangki Suchiang ◽  
Venkatesan Arul
Keyword(s):  
Caenorhabditis Elegans ◽  
Chemical Characterization ◽  
Aging Effects ◽  
Weissella Cibaria ◽  
Physico Chemical

Laboratory Methods for the Physico-Chemical Characterization of Recombinant Allergens as Reference Standards

Alergologia ◽  
2020 ◽  
Vol 1 (4) ◽  
pp. 7
Author(s):  
Mariana Vieru ◽  
Florin-Dan Popescu ◽  
Laura Haidar ◽  
Carmen Bunu-Panaitescu
Keyword(s):  
Chemical Characterization ◽  
Reference Standards ◽  
Recombinant Allergens ◽  
Laboratory Methods ◽  
Physico Chemical

Mineralogical and physico-chemical characterization of a sintered feldspathic sand

2010 ◽  
Vol 35 (5) ◽  
pp. 261-267 ◽  
Author(s):  
Wissemn Gallala ◽  
Mohamed Essghaier Gaied ◽  
Borhen Kchaou
Keyword(s):  
Chemical Characterization ◽  
Physico Chemical

Physical - Chemical Issues of Cephalosporin Intercalated Nanoparticles for Life - Threatening Infections Treatment

2001 ◽  
Vol 71 (3) ◽  
pp. 342-349
Author(s):  
Lucian Eva ◽  
Letitia Doina Duceac ◽  
Liviu Stafie ◽  
Constantin Marcu ◽  
Geta Mitrea ◽  
...  
Keyword(s):  
Chemical Characterization ◽  
Advanced Characterization ◽  
Generation Cephalosporin ◽  
Fourth Generation ◽  
Exchange Method ◽  
Physico Chemical ◽  
Life Threatening ◽  
Double Hydroxide ◽  
Double Hydroxides

The fourth generation cephalosporin antibacterial agent, cefepime, was loaded into layered double hydroxides for enhancing antibiotic efficiency, reducing side effects, as well as achieving the sustained release property. The intercalation of antibiotic into the inter-gallery of ZnAl-layered double hydroxide (LDH) was carried out using ion exchange method, by this constituting a nano-sized organic-inorganic hybrid material for a controlled release novel formulation. Although cefepime is a broad spectrum antibiotic, it has various adverse effects and a significant degradation rate. Thus, the preparation and physico-chemical characterization of nanomaterials able to intercalate this drug is an important study for medical and pharmaceutical field. The antibiotic inclusion into LDHs nanostructure was confirmed by advanced characterization techniques and the release profile of cefepime was analysed with the respect to pH of the simulated media.

scholarly journals Physico-Chemical Characterization and Biopharmaceutical Evaluation of Lipid-Poloxamer-Based Organogels for Curcumin Skin Delivery

2019 ◽  
Vol 10 ◽  
Author(s):  
Aryane Alves Vigato ◽  
Samyr Machado Querobino ◽  
Naially Cardoso de Faria ◽  
Ana Carolina Bolela Bovo Candido ◽  
Lizandra Guidi Magalhães ◽  
...  
Keyword(s):  
Chemical Characterization ◽  
Skin Delivery ◽  
Physico Chemical

scholarly journals Physico-Chemical Characterization and Antimicrobial Properties of Hybrid Film Based on Saponite and Phloxine B

Molecules ◽  
2021 ◽  
Vol 26 (2) ◽  
pp. 325
Author(s):  
Nitin Chandra teja Dadi ◽  
Matúš Dohál ◽  
Veronika Medvecká ◽  
Juraj Bujdák ◽  
Kamila Koči ◽  
...  
Keyword(s):  
Hybrid Film ◽  
Antimicrobial Properties ◽  
Chemical Characterization ◽  
Layered Silicate ◽  
Contact Angles ◽  
Exchange Capacity ◽  
Resistant Bacteria ◽  
Hybrid Films ◽  
Water Contact ◽  
Physico Chemical

This research was aimed at the preparation of a hybrid film based on a layered silicate saponite (Sap) with the immobilized photosensitizer phloxine B (PhB). Sap was selected because of its high cation exchange capacity, ability to exfoliate into nanolayers, and to modify different surfaces. The X-ray diffraction of the films confirmed the intercalation of both the surfactant and PhB molecules in the Sap film. The photosensitizer retained its photoactivity in the hybrid films, as shown by fluorescence spectra measurements. The water contact angles and the measurement of surface free energy demonstrated the hydrophilic nature of the hybrid films. Antimicrobial effectiveness, assessed by the photodynamic inactivation on hybrid films, was tested against a standard strain and against methicillin-resistant bacteria of Staphylococcus aureus (MRSA). One group of samples was irradiated (green LED light; 2.5 h) and compared to nonirradiated ones. S. aureus strains manifested a reduction in growth from 1-log10 to over 3-log10 compared to the control samples with Sap only, and defects in S. aureus cells were proven by scanning electron microscopy. The results proved the optimal photo-physical properties and anti-MRSA potential of this newly designed hybrid system that reflects recent progress in the modification of surfaces for various medical applications.

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