scholarly journals Family-Based Genome-Wide Association Study of South Indian Pedigrees SupportsWNT7Bas a Central Corneal Thickness Locus

2018 ◽  
Vol 59 (6) ◽  
pp. 2495 ◽  
Author(s):  
Bao Jian Fan ◽  
Xueli Chen ◽  
Nisha Sondhi ◽  
P. Ferdinamarie Sharmila ◽  
Nagasamy Soumittra ◽  
...  
Keyword(s):  
Association Study ◽  
Central Corneal Thickness ◽  
Genome Wide Association Study ◽  
Corneal Thickness ◽  
Genome Wide Association ◽  
South Indian ◽  
Genome Wide ◽  
Family Based

scholarly journals A Genome-Wide Association Study of Central Corneal Thickness in Latinos

2013 ◽  
Vol 54 (4) ◽  
pp. 2435 ◽  
Author(s):  
Xiaoyi Gao ◽  
W. James Gauderman ◽  
Yutao Liu ◽  
Paul Marjoram ◽  
Mina Torres ◽  
...  
Keyword(s):  
Association Study ◽  
Central Corneal Thickness ◽  
Genome Wide Association Study ◽  
Corneal Thickness ◽  
Genome Wide Association ◽  
Genome Wide ◽  
A Genome

scholarly journals Genome-wide association study identifiesWNT7Bas a novel locus for central corneal thickness in Latinos

2016 ◽  
pp. ddw319 ◽  
Author(s):  
Xiaoyi Gao ◽  
Drew R. Nannini ◽  
Kristen Corrao ◽  
Mina Torres ◽  
Yii-Der I. Chen ◽  
...  
Keyword(s):  
Association Study ◽  
Central Corneal Thickness ◽  
Genome Wide Association Study ◽  
Corneal Thickness ◽  
Genome Wide Association ◽  
Genome Wide

Research and Findings

2010 ◽  
Vol 14 (12) ◽  
pp. 54-55
Keyword(s):  
Multidrug Resistance ◽  
Association Study ◽  
Central Corneal Thickness ◽  
Genome Wide Association Study ◽  
Corneal Thickness ◽  
Molecular Simulations ◽  
Genome Wide Association ◽  
Genome Wide

The Benefits of Perforin Revealed. Singapore Scientists First to Perform the Largest Genome-wide Association Study on Central Corneal Thickness. Molecular Simulations Confirm Role of Functional Rotation in Multidrug Resistance.

scholarly journals A family-based genome-wide association study of chronic rhinosinusitis with nasal polyps implicates several genes in the disease pathogenesis

PLoS ONE ◽  
2017 ◽  
Vol 12 (12) ◽  
pp. e0185244 ◽  
Author(s):  
Anton Bohman ◽  
Julius Juodakis ◽  
Martin Oscarsson ◽  
Jonas Bacelis ◽  
Mats Bende ◽  
...  
Keyword(s):  
Association Study ◽  
Chronic Rhinosinusitis ◽  
Nasal Polyps ◽  
Genome Wide Association Study ◽  
Genome Wide Association ◽  
Disease Pathogenesis ◽  
Genome Wide ◽  
Family Based

scholarly journals P1-142: A GENOME-WIDE ASSOCIATION STUDY IMPLICATES EHPA6 FOR ALZHEIMER DISEASE IN FAMILY-BASED ANALYSIS

2019 ◽  
Vol 15 ◽  
pp. P291-P292
Author(s):  
Donghe Li ◽  
John Farrell ◽  
Lindsay A. Farrer ◽  
Gyungah R. Jun ◽  
Sungho Won
Keyword(s):  
Alzheimer Disease ◽  
Association Study ◽  
Genome Wide Association Study ◽  
Genome Wide Association ◽  
Genome Wide ◽  
A Genome ◽  
Family Based

scholarly journals Family-based genome-wide association study for simulated data of Framingham Heart Study

2009 ◽  
Vol 3 (S7) ◽  
Author(s):  
Hongyan Xu ◽  
George Mathew ◽  
Varghese George
Keyword(s):  
Association Study ◽  
Framingham Heart Study ◽  
Genome Wide Association Study ◽  
Simulated Data ◽  
Genome Wide Association ◽  
Genome Wide ◽  
Heart Study ◽  
Family Based

scholarly journals Genome-wide association study using family-based cohorts identifies the WLS and CCDC170/ESR1 loci as associated with bone mineral density

BMC Genomics ◽  
2016 ◽  
Vol 17 (1) ◽  
Author(s):  
Benjamin H. Mullin ◽  
John P. Walsh ◽  
Hou-Feng Zheng ◽  
Suzanne J. Brown ◽  
Gabriela L. Surdulescu ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Association Study ◽  
Bone Mineral ◽  
Genome Wide Association Study ◽  
Genome Wide Association ◽  
Mineral Density ◽  
Genome Wide ◽  
Family Based

A family-based genome-wide association study reveals an association of spondyloarthritis with MAPK14

2016 ◽  
Vol 76 (1) ◽  
pp. 310-314 ◽  
Author(s):  
Félicie Costantino ◽  
Alice Talpin ◽  
Roula Said-Nahal ◽  
Ariane Leboime ◽  
Elena Zinovieva ◽  
...  
Keyword(s):  
Association Study ◽  
Genome Wide Association Study ◽  
Genome Wide Association ◽  
P Value ◽  
Nucleotide Polymorphisms ◽  
Genetic Associations ◽  
Gwas Study ◽  
Genome Wide ◽  
Multiplex Families ◽  
Family Based

ObjectiveMore than 40 loci have been associated with ankylosing spondylitis (AS), but less is known about genetic associations in spondyloarthritis (SpA) as a whole. We conducted a family-based genome-wide association study (GWAS) to identify new non-major histocompatibility complex (MHC) genetic factors associated with SpA.Methods906 subjects from 156 French multiplex families, including 438 with SpA, were genotyped using Affymetrix 250K microarrays. Association was tested with Unphased. The best-associated non-MHC single nucleotide polymorphisms (SNPs) were then genotyped in two independent familial cohorts (including 215 French and 294 North American patients with SpA, respectively) to replicate associations.Results43 non-MHC SNPs yielded an association signal with SpA in the discovery cohort (p<1×10−4). In the extension studies, association was replicated at a nominal p value of p<0.05 for 16 SNPs in the second cohort and for three SNPs in the third cohort. Combined analysis identified an association close to genome-wide significance between rs7761118, an intronic SNP of MAPK14, and SpA (p=3.5×10−7). Such association appeared to be independent of HLA-B27.ConclusionsWe report here for the first time a family-based GWAS study on SpA and identified an associated polymorphism near MAPK14. Further analyses are needed to better understand the functional basis of this genetic association.

scholarly journals A family-based, genome-wide association study of young-onset breast cancer: inherited variants and maternally mediated effects

2016 ◽  
Vol 24 (9) ◽  
pp. 1316-1323 ◽  
Author(s):  
Katie M O'Brien ◽  
Min Shi ◽  
Dale P Sandler ◽  
Jack A Taylor ◽  
Dmitri V Zaykin ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Association Study ◽  
Genome Wide Association Study ◽  
Genome Wide Association ◽  
Young Onset ◽  
Mediated Effects ◽  
Genome Wide ◽  
Family Based

Family-based genome-wide association study in Patagonia confirms the association of theDMDlocus and cleft lip and palate

2015 ◽  
Vol 123 (5) ◽  
pp. 381-384 ◽  
Author(s):  
Renata F. Fonseca ◽  
Flávia M. de Carvalho ◽  
Fernando A. Poletta ◽  
David Montaner ◽  
Joaquin Dopazo ◽  
...  
Keyword(s):  
Association Study ◽  
Cleft Lip ◽  
Genome Wide Association Study ◽  
Cleft Lip And Palate ◽  
Genome Wide Association ◽  
Genome Wide ◽  
Family Based
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