Baclofen-induced growth hormone release in major depression: relationship to dexamethasone suppression test result

1993 ◽  
Vol 150 (11) ◽  
pp. 1728-1730 ◽  
Keyword(s):  
Growth Hormone ◽  
Major Depression ◽  
Dexamethasone Suppression Test ◽  
Hormone Release ◽  
Growth Hormone Release ◽  
Suppression Test ◽  
Dexamethasone Suppression ◽  
Test Result

The corticotropin releasing factor stimulation test in patients with major depression: Relationship to dexamethasone suppression test results

Depression ◽  
1993 ◽  
Vol 1 (3) ◽  
pp. 133-136 ◽  
Author(s):  
K. Ranga R. Krishnan ◽  
Krishnaiah Rayasam ◽  
Deborah Reed ◽  
Mark Smith ◽  
Phillip Chapell ◽  
...  
Keyword(s):  
Major Depression ◽  
Dexamethasone Suppression Test ◽  
Corticotropin Releasing Factor ◽  
Stimulation Test ◽  
Test Results ◽  
Suppression Test ◽  
Dexamethasone Suppression

Endocrine and behavioural responses to methylphenidate in depression

1986 ◽  
Vol 16 (3) ◽  
pp. 531-540 ◽  
Author(s):  
Peter R. Joyce ◽  
Richard A. Donald ◽  
M. Gary Nicholls ◽  
John H. Livesey ◽  
Robyn M. Abbott
Keyword(s):  
Growth Hormone ◽  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Dexamethasone Suppression Test ◽  
Cortisol Response ◽  
Major Depressive ◽  
Behavioural Responses ◽  
Baseline Cortisol ◽  
Suppression Test ◽  
Dexamethasone Suppression

SynopsisTwenty patients with a major depressive disorder and 20 control subjects were subjected to a 1 mg dexamethasone suppression test (DST) and a challenge with intravenous (IV) methylphenidate (MP)(0·3 mg/kg). None of the controls, but 9 depressives, were DST non-suppressors. Among the depressives there were correlations between DST-cortisol and baseline (4 p.m.) levels of cortisol, growth hormone, prolactin and adrenaline. Compared with the controls the depressives had a decreased cortisol response and an enhanced adrenaline response to the MP challenge. The decreased cortisol response was not related to either DST-cortisol or baseline cortisol, but was correlated with the mood response to MP.

The dexamethasone suppression test in major depression: clinical and polysomnographic findings

1993 ◽  
Vol 3 (3) ◽  
pp. 338-339
Author(s):  
Ph.P. Hubain ◽  
L. Staner ◽  
M. Dramaix ◽  
M. Kerkhofs ◽  
C. Van Veeren ◽  
...  
Keyword(s):  
Major Depression ◽  
Dexamethasone Suppression Test ◽  
Suppression Test ◽  
Dexamethasone Suppression

Measured Weight Loss and the Dexamethasone Suppression Test*

1989 ◽  
Vol 34 (7) ◽  
pp. 707-709 ◽  
Author(s):  
Sidney H. Kennedy ◽  
Paul E. Garfinkel ◽  
Stephen Stokl ◽  
Carrol A. Whynot
Keyword(s):  
Weight Loss ◽  
Major Depression ◽  
Prospective Study ◽  
Dexamethasone Suppression Test ◽  
Measured Weight ◽  
Suppression Test ◽  
A Prospective Study ◽  
Dexamethasone Suppression

In a prospective study of 28 subjects with major depression, weight was significantly related to nonsuppression in the dexamethasone suppression test (DST) on admission and seven days later. However, changes in weight between these two times did not alter the DST status.

The Dexamethasone Suppression Test and Suicidal Patients

1985 ◽  
Vol 147 (4) ◽  
pp. 419-423 ◽  
Author(s):  
Jon Ennis ◽  
Rosemary A. Barnes ◽  
Sidney Kennedy
Keyword(s):  
Substance Abuse ◽  
Major Depression ◽  
Patient Population ◽  
Tricyclic Antidepressants ◽  
Dexamethasone Suppression Test ◽  
The Poor ◽  
Suppression Test ◽  
Suicidal Patients ◽  
Dexamethasone Suppression

The dexamethasone suppression test (DST) was used in an in-patient crisis unit to determine whether the test could identify suicidal patients who might benefit from tricyclic antidepressants. DST results, DSM-III diagnoses, and measures of symptom levels were obtained for 72 patients admitted for a 3–5 day period; 31 were non-suppressors. Abnormal DST results were not related to DSM-III diagnosis or to scores on measures of depression and symptom levels. Only three patients met DSM-III criteria for major depression with melancholia; 26 patients had a diagnosis of alcohol or substance abuse. The poor specificity of the DST in this patient population suggests that its routine use in such patients could be highly misleading.

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