Effects of Atrial Pacing on QT Dispersion in Patients with Coronary Artery Disease Without Angina Pectoris and ST Segment Depression

Angiology ◽  
2001 ◽  
Vol 52 (6) ◽  
pp. 393-398
Author(s):  
Ahmet Duran Demir ◽  
Kubilay Senen ◽  
Yücel Balbay ◽  
Mustafa Soylu ◽  
Hakan Tikiz ◽  
...  
e-CliniC ◽  
2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Cathleen S. Kalangi ◽  
Edmond L. Jim ◽  
Victor F.F. Joseph

Abstract: Arrhythmia is an abnormal heart rhythm which refer to every disturbance in frequency, regularity, original location or electrical impulses conduction of the heart. Ischemic myocardium characterized by ionic and biochemical alterations creates an unstable electrical substrate capable of initiating and sustaining arrhythmias, meanwhile infarction creates areas of electrical inactivity and blocks conduction, which also promotes arrhythmogenesis. This study was aimed to obtain the description of arrhythmias in coronary artery disease patients at Prof. Dr. R. D. Kandou Hospital Manado from 1 January 2015 to 31 December 2015. This was a descriptive retrospective study. There were 101 data of patients with Coronary Artery Disease (CAD) associated with arrhythmia, as follows: 57 cases (56%) of Stable Angina Pectoris (SAP), 6 cases (6%) of Old Myocardial Infarction (OMI), 16 cases (16%) of Unstable Angina Pectoris (UAP), 20 cases (20%) of Non ST Segment Elevation Myocardial Infarction (NSTEMI), and 2 cases (2%) of ST Segment Elevation Myocardial Infarction (STEMI). The majority of cases were males (66%) and aged 51-60 years old (35%). There were 62 cases (41%) of CAD patients associated with arrhythmia that had hypertension as the highest risk factor and 19 cases (12%) for smoker as the lowest risk factor. The highest number of patients was Angina Pectoris Stabil (APS), and the dominant arrhythmia was Premature Ventricular Contraction (PVC).Keywords: description, arrhythmia, coronary artery disease Abstrak: Aritmia merupakan gangguan irama jantung yang merujuk kepada setiap gangguan frekuensi, regularitas, lokasi asal atau konduksi impuls listrik jantung. Iskemik miokardium ditandai dengan perubahan ion dan biokimiawi, mengakibatkan aktivitas listrik yang tidak stabil yang memicu dan mempertahankan aritmia, dan infark menciptakan daerah aktif dan blok konduksi listrik, yang juga memromosikan aritmogenesis. Penelitian ini bertujuan untuk mengetahui gambaran aritmia pada pasien penyakit jantung koroner (PJK) di RSUP Prof. Dr. R. D. Kandou Manado periode 1 Januari 2015-31 Desember 2015. Jenis penelitian ialah deskriptif retrospektif. Hasil penelitian mendapatkan 101 data pasien PJK yang mengalami aritmia, diantaranya Angina Pektoris Stabil (APS) 57 kasus (56%), Old Myocardial Infarction (OMI) 6 kasus (6%), Unstable Angina Pectoris (UAP) 16 kasus (16%), Non ST Segment Elevation Myocardial Infarction (NSTEMI) 20 kasus (20%), dan ST Segment Elevation Myocardial Infarction (STEMI) 2 kasus (2%). Mayoritas kasus ialah jenis kelamin laki-laki (66%), usia 51-60 tahun (35%). Faktor risiko tertinggi pada pasien PJK dengan aritmia ialah hipertensi (41%) dan terendah ialah merokok (12%). Kasus tertinggi ialah APS, dengan aritmia terbanyak ialah Premature Ventricular Contraction (PVC), Kata kunci: gambaran, aritmia, penyakit jantung koroner


1999 ◽  
Vol 63 (7) ◽  
pp. 517-521 ◽  
Author(s):  
Mitsuisa Yoshimura ◽  
Koji Matsumoto ◽  
Mitsuaki Watanabe ◽  
Naoko Yamashita ◽  
Eiko Sanuki ◽  
...  

1988 ◽  
Vol 61 (13) ◽  
pp. 989-993 ◽  
Author(s):  
Joan Barry ◽  
Andrew P. Selwyn ◽  
Elizabeth G. Nabel ◽  
Michael B. Rocco ◽  
Kimberely Mead ◽  
...  

2000 ◽  
Vol 55 (6) ◽  
pp. 335-339 ◽  
Author(s):  
Mehmet ÜLGEN ◽  
Aziz KARADEDE ◽  
Sait ALAN ◽  
A. Vahip TEMAMOĞULARI ◽  
Aziz KARABULUT ◽  
...  

2020 ◽  
Vol 16 ◽  
Author(s):  
George Kassimis ◽  
Grigoris V. Karamasis ◽  
Athanasios Katsikis ◽  
Joanna Abramik ◽  
Nestoras Kontogiannis ◽  
...  

Coronary artery disease (CAD) remains the leading cause of cardiovascular death in octogenarians. This group of patients represents nearly a fifth of all patients treated with percutaneous coronary intervention (PCI) in real-world practice. Octogenarians have multiple risk factors for CAD and often greater myocardial ischemia than younger counterparts, with a potential of an increased benefit from myocardial revascularization. Despite this, octogenarians are routinely under-treated and belittled in clinical trials. Age does make a difference to PCI outcomes in older people, but it is never the sole arbiter of any clinical decision, whether in relation to the heart or any other aspect of health. The decision when to perform revascularization in elderly patients and especially in octogenarians is complex and should consider the patient on an individual basis, with clarification of the goals of the therapy and the relative risks and benefits of performing the procedure. In ST-segment elevation myocardial infarction (MI), there is no upper age limit regarding urgent reperfusion and primary PCI must be the standard of care. In non-ST-segment elevation acute coronary syndromes, a strict conservative strategy must be avoided; whereas the use of a routine invasive strategy may reduce the occurrence of MI and need for revascularization at follow-up, with no established benefit in terms of mortality. In stable CAD patients, invasive therapy on top of the optimal medical therapy seems better in symptom relief and quality of life. This review summarizes the available data on percutaneous revascularization in the elderly patients and particularly in octogenarians, including practical considerations on PCI risk secondary to ageing physiology. We also analyse technical difficulties met when considering PCI in this cohort and the ongoing need for further studies to ameliorate risk stratification and eventually outcomes in these challenging patients.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Ximena Morales ◽  
Diego Garnica ◽  
Daniel Isaza ◽  
Nicolas Isaza ◽  
Felipe Durán-Torres

Abstract Background Abiraterone is a medication frequently used for metastatic castrate-resistant prostate cancer. We report a case of non-sustained episodes of TdP associated with severe hypokalemia due to androgen-deprivation therapy. Few case presentations describe this association; the novelty lies in the potentially lethal cardiovascular events among cancer patients receiving hormonal therapy. Case presentation A 70-year-old male presented with recurrent syncope without prodrome. ECG revealed frequent ventricular ectopy, non-sustained episodes of TdP, and severe hypomagnesemia and hypokalemia. During potassium and magnesium infusion for repletion, the patient underwent temporary transvenous atrial pacing. As part of the work-up, coronary angiography revealed a mild coronary artery disease, and transthoracic echocardiogram showed a moderately depressed ejection fraction. After electrolyte disturbances were corrected, the QT interval normalized, and transvenous pacing was no longer necessary. Abiraterone was discontinued during the admission, and the patient returned to baseline. Conclusions Cancer treatment is complex and requires a multidisciplinary approach. We presented a case of non-sustained TdP associated with androgen-deprivation therapy in an elderly patient with mild coronary artery disease and moderately reduced ejection fraction. Close follow-up and increased awareness are required in patients with hormonal treatment, especially in the setting of other cardiovascular risk factors.


Angiology ◽  
2021 ◽  
pp. 000331972199885
Author(s):  
Omer Faruk Cirakoglu ◽  
Ayşe Gül Karadeniz ◽  
Ali Riza Akyüz ◽  
Cihan Aydın ◽  
Sinan Şahin ◽  
...  

Accurately identifying coronary artery disease (CAD) is the key element in guiding the work-up of patients with suspected angina. Thickening of the arterial wall is a hallmark of atherosclerosis. Therefore, the main purpose of this study was to determine whether abdominal aortic intima-media thickness (AAIMT), which is the earliest zone of atherosclerotic manifestations, has a predictive value in CAD severity. A total of 255 consecutive patients who were referred for invasive coronary angiography due to suspected stable angina pectoris were prospectively included in the study. B-mode ultrasonography was used to determine AAIMT before coronary angiography. Coronary artery disease severity was assessed with the SYNTAX score (SS). A history of hypertension, age, dyslipidemia, and higher AAIMT (odds ratio: 2.570; 95%CI 1.831-3.608; P < .001) were independent predictors of intermediate or high SS. An AAIMT <1.3 mm had a negative predictive value of 98% for the presence of intermediate or high SS and 83% for obstructive CAD. In conclusion, AAIMT showed a significant and independent predictive value for intermediate or high SS. Therefore, AAIMT may be a noninvasive and useful tool for decision-making by cardiologists (eg, to use a more invasive approach).


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