Synovial Sarcomas of the Head and Neck

1992 ◽  
Vol 101 (4) ◽  
pp. 367-370 ◽  
Author(s):  
Rosario Carrillo ◽  
Jose Luis Rodriguez-Peralto ◽  
John G. Batsakis
Keyword(s):  
Natural History ◽  
Head And Neck ◽  
Synovial Sarcoma ◽  
High Grade ◽  
Appreciable Difference ◽  
Biologic Activity ◽  
History Of ◽  
Synovial Sarcomas ◽  
Synovial Tissues

Springing from mesenchyme rather than mature synovial tissues, synovial sarcomas are high-grade neoplasms that express epithelial as well as supporting tissue features. Accordingly, their histologic phenotypes can be epithelial, stromal, or mixed. Between 3% and 10% of all synovial sarcomas originate in the head and neck, particularly from parapharyngeal sites. These is no appreciable difference in biologic activity between synovial sarcomas of the head and neck and those arising from other anatomic sites. Five-year survivals are misleadingly optimistic and do not adequately reflect the natural history of the sarcoma. Synovial sarcoma is known to metastasize late, and few patients survive that event.

The natural history of untreated squamous cell carcinoma of the head and neck: how we do it

2011 ◽  
Vol 36 (4) ◽  
pp. 384-388 ◽  
Author(s):  
J.-P. Jeannon ◽  
E. Ofu ◽  
A. Balfour ◽  
J. Bowman ◽  
R. Simo
Keyword(s):  
Squamous Cell Carcinoma ◽  
Natural History ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
History Of

Natural history of high grade pin in prostate biopsies

2002 ◽  
Vol 1 (1) ◽  
pp. 119
Author(s):  
Hubert Volgger ◽  
Wolfgang Horninger ◽  
Hannes Steiner ◽  
Hermann Rogatsch ◽  
Georg Bartsch
Keyword(s):  
Natural History ◽  
High Grade ◽  
Prostate Biopsies ◽  
History Of

The Natural History of Metastatic Synovial Sarcoma

1982 ◽  
Vol &NA; (164) ◽  
pp. 257???260 ◽  
Author(s):  
JAMES R. RYAN ◽  
LAURENCE H. BAKER ◽  
ROBERT S. BENJAMIN
Keyword(s):  
Natural History ◽  
Synovial Sarcoma ◽  
History Of

The Natural History of Soft Tissue Hypertrophy, Bony Hypertrophy, and Nodule Formation in Patients With Untreated Head and Neck Capillary Malformations

2015 ◽  
Vol 41 (11) ◽  
pp. 1241-1245 ◽  
Author(s):  
Jeong Woo Lee ◽  
Ho Yun Chung ◽  
Eric W. Cerrati ◽  
Teresa M. O ◽  
Milton Waner
Keyword(s):  
Soft Tissue ◽  
Natural History ◽  
Head And Neck ◽  
Nodule Formation ◽  
History Of

scholarly journals Pediatric Synovial Sarcoma in the Retropharyngeal Space: A Rare and Unusual Presentation

2015 ◽  
Vol 2015 ◽  
pp. 1-4
Author(s):  
Sanjay Vaid ◽  
Neelam Vaid ◽  
Sanjay Desai ◽  
Varada Vaze
Keyword(s):  
Head And Neck ◽  
Synovial Sarcoma ◽  
Pediatric Population ◽  
Neck Region ◽  
Retropharyngeal Space ◽  
Imaging Findings ◽  
Head And Neck Region ◽  
English Medical Literature ◽  
Synovial Sarcomas ◽  
First Time

Synovial sarcomas in the head and neck are extremely rare tumors, especially in the pediatric population. 3–5% of synovial sarcomas occur in the head and neck region displaying varied imaging and histopathological features resulting in frequent misdiagnosis. These tumors have a poor prognosis; hence early diagnosis and accurate classification based on imaging, histopathology, and immunohistochemistry are critical for prompt treatment. To the best of our knowledge, imaging findings of pediatric retropharyngeal lipomatous synovial sarcoma have not been reported to date in English medical literature. We report, for the first time, a rare case of retropharyngeal lipomatous synovial sarcoma in a ten-year-old child and discuss the case-specific imaging findings in our patient using magnetic resonance imaging and computed tomography.

scholarly journals Natural history of histologically confirmed high-grade cervical intraepithelial neoplasia during pregnancy: meta-analysis

BMJ Open ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. e048055
Author(s):  
Cheng Chen ◽  
Yu Xu ◽  
Wu Huang ◽  
Yi Du ◽  
Cui Hu
Keyword(s):  
Natural History ◽  
Cervical Intraepithelial Neoplasia ◽  
Meta Analysis ◽  
Intraepithelial Neoplasia ◽  
Progression Rate ◽  
Lower Grade ◽  
High Grade ◽  
Regression Rate ◽  
Persistence Rate ◽  
History Of

ObjectivesThis study aimed to conduct a meta-analysis of estimates of the natural history of high-grade cervical intraepithelial neoplasia (CIN) during pregnancy.SettingStudies examining the clinical courses of histologically confirmed high-grade CIN during pregnancy.ParticipantsWe searched PubMed, Web of Science and Embase for eligible studies. Studies were included if they reported the data regarding the natural history of histologically confirmed high-grade CIN during pregnancy. Final estimates were from the meta-analysis of 10 eligible studies.Primary outcome measuresThe regression rate, persistence rate and progression rate of histologically proven untreated high-grade CIN during pregnancy.ResultsA total of 10 original studies were included in this meta-analysis. During pregnancy, the regression rate, persistence rate and progression rate of high-grade CIN were 40% (95% CI 35% to 45%), 59% (95% CI 54% to 64%) and 1% (95% CI 0% to 2%), respectively. There was moderate heterogeneity among the studies. The results of the subgroup meta-analysis show that the pooled rates of regression and persistence during pregnancy were 59% (95% CI 54% to 65%) and 40% (95% CI 35% to 45%) for CIN2, and 29% (95% CI 25% to 33%) and 70% (95% CI 65% to 73%) for CIN3.ConclusionsDuring pregnancy, the majority of histologically confirmed high-grade CIN would be persistent or regressed to lower grade CIN or normal. However, it is still worth noting that a small percentage of high-grade CIN would progress to cervical cancer during pregnancy.

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