Laryngeal Radionecrosis versus Recurrent Cancer: A Clinical Approach

1998 ◽  
Vol 107 (4) ◽  
pp. 293-296 ◽  
Author(s):  
W. Frederick McGuirt ◽  
Kathryn M. Greven ◽  
John W. Keyes ◽  
Daniel W. Williams ◽  
Nat Watson

A group of 38 patients was studied by positron emission tomography utilizing fluorine18-labeled deoxyglucose (FDG-PET) scanning to examine the ability to differentiate postirradiation laryngeal recurrent cancer from radionecrosis. The resulting 79% correct diagnosis showed the technique to be far superior to conventional computed tomography scanning (61%) and clinical examination (43%). An algorithmic approach to evaluating and treating patients with radionecrosis and/or recurrent cancer by utilizing FDG-PET scanning is presented.

2012 ◽  
Vol 19 (2) ◽  
pp. C19-C22 ◽  
Author(s):  
Maria E Cabanillas ◽  
Steven I Sherman

In the February 2011 issue of Endocrine-Related Cancer, Deandreis et al. reported that increased FDG uptake was prognostic in patients with metastatic thyroid cancer. Fludeoxyglucose-positron emission tomography (FDG-PET) is routinely used in the staging and follow-up of patients with cancer. This study gives further evidence for the role of FDG-PET scanning in metastatic thyroid cancer, especially to identify patients with aggressive disease requiring systemic therapy.


2006 ◽  
Vol 26 (2) ◽  
pp. 224-230 ◽  
Author(s):  
Ruth M. Tarzi ◽  
John W. Frank ◽  
Sohail Ahmad ◽  
Jeremy B. Levy ◽  
Edwina A. Brown

Objective We studied the effectiveness of 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) in detecting inflammation in known or suspected cases of sclerosing peritonitis in patients on peritoneal dialysis (PD). Design We undertook FDG-PET scanning in PD patients presenting with symptoms or signs suggestive of sclerosing peritonitis (SP), and in patients on long-term PD with no symptoms of SP. Setting The study was performed in a PD unit in a tertiary-care hospital. Patients and Methods Three patients with known or strongly suspected SP underwent FDG-PET scans, 1 within 3 months of presentation with symptoms and 2 who were scanned more than 9 months after presentation. One patient was scanned at an early and a late time point. Five patients who had been on PD for more than 5 years and who were asymptomatic also underwent FDG-PET scanning. Scans were interpreted by a specialist in nuclear medicine. Results The scan performed in the early stages of SP showed increased peritoneal uptake. However, three scans taken more than 9 months after presentation with suspected SP showed mild peritoneal abnormalities only. One of 5 asymptomatic long-term PD patients showed increased peritoneal uptake associated with loss of ultrafiltration and high transporter status. Conclusions FDG-PET scanning may be a useful adjunct in the diagnosis of the acute phase of SP. More study is needed to define its role in the diagnosis of SP in asymptomatic PD patients.


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