scholarly journals Serum Antioxidant Activity in Normal and Abnormal Subjects

1979 ◽  
Vol 16 (1-6) ◽  
pp. 299-306 ◽  
Author(s):  
L. M. Cranfield ◽  
J. L. Gollan ◽  
A. G. White ◽  
T. L. Dormandy
Keyword(s):  
Antioxidant Activity ◽  
Serum Iron ◽  
Binding Capacity ◽  
Normal Subjects ◽  
Serum Copper ◽  
Iron Binding ◽  
Thalassaemia Major ◽  
Hepatolenticular Degeneration ◽  
Tocopherol Concentration ◽  
Iron Binding Capacity

Serum antioxidant activity (AOA) was correlated with the serum caeruloplasmin and serum copper concentration and with the total and available serum iron-binding capacity in 313 normal and abnormal subjects. In all groups except in patients with Wilson's disease (hepatolenticular degeneration) there was a highly significant direct correlation between serum AOA and serum caeruloplasmin concentration. A statistically significant direct correlation between serum AOA and the available iron-binding capacity of serum was found only in normal subjects and in children with thalassaemia major and iron overload. There was no correlation between serum AOA and the serum tocopherol concentration in any of the groups studied.

STUDIES OF IRON REQUIREMENTS IN INFANTS AND CHILDREN

PEDIATRICS ◽  
1954 ◽  
Vol 13 (2) ◽  
pp. 107-125
Author(s):  
PHILLIP STURGEON
Keyword(s):  
Serum Iron ◽  
Binding Capacity ◽  
Serum Copper ◽  
Total Serum ◽  
Normal Infant ◽  
Iron Binding ◽  
Essentially Normal ◽  
Free Erythrocyte Protoporphyrin ◽  
Erythrocyte Protoporphyrin ◽  
Iron Binding Capacity

On an average the newborn infant serum compared to the normal adult male is hyperferremic (S.I. 193 µg./100 cc.), hypocupremic (S.C.51µg./100 cc.), and his free erythrocyte protoporphyrin is increased about two-fold (E.P. 55 µg./100 cc.). His total serum iron-binding capacity appears to be 50% or more saturated. At 12 hours of age marked hypoferremia (S.I. 46 µg./100 cc.) is present and the total iron-binding capacity as measured in this study is 100% saturated. There is slight, if any, change in the serum copper or erythrocyte protoporphyrin during the first few hours or days of life. From two weeks through one month of age an essentially normal pattern is present except for the slightly elevated (two-fold) protoporphyrin. By 4 to 10 months of age, on an average, the normal infant has the pattern characteristic of infancy, namely, hypoferremia (S.I., 50 µ. g/100 cc.), hypercupremia (S.C., 146 µg./100 cc.), reduced saturation of the total serum iron-binding capacity (12%) and elevated free erythrocyte protoporphyrin (E.P., 70 µg./100 cc.). Extreme ranges in values are found in different individuals at most ages. The suggested explanation for these findings is that on an average, the normal infant relative to the adult is totally depleted of his iron reserve and that his state of "physiologic anemia" constitutes an additional, but lesser, iron deficit.

scholarly journals Evaluation of Some Biochemical parameters in Clinically Normal lactating and Ovine Mastitis

2014 ◽  
Vol 38 (2) ◽  
pp. 74-78
Author(s):  
AL-Hadithy H. AH.
Keyword(s):  
Biochemical Parameters ◽  
Serum Iron ◽  
Binding Capacity ◽  
Transferrin Saturation ◽  
Serum Copper ◽  
Reference Ranges ◽  
Iron Binding ◽  
Biochemical Tests ◽  
Clinically Normal ◽  
Iron Binding Capacity

     The aim of the present work was to determine the serum iron, total iron binding capacity (TIBC), unbound iron binding capacity (UIBC), transferrin saturation percentage (TS%) and Serum Copper in normal lactating and Ovine mastitis. The study was conducted on 50 clinically normal lactating and 50 ewes affected with staphylococcal mastitis (19 clinical and 31 subclinical), both groups aged 2-5 years in Salah Al-Din governorate. The blood samples were collected from jugular vein during the period October 2012 untill April 2013. The separated sera were directly used for measurement of investigated biochemical tests. The results showed that the ranges and means ± SE of normal lactating and Ovine mastitis were as follows; serum iron 29.81-39. 63µmol /L and 33.38 ± 0.4 µmol /L, 8.76 - 34.11 µmol /L and 20.42 ± 0.98 µmol /L respectively, TIBC 44.7-79.89 µmol /L and  62.03 ±1.65µmol /L, 43.24 - 125.72 µmol /L and 91.24 ± 2.49 µmol /L respectively, UIBC 14.71 - 40.27 µmol /L and 28.57 ± 1.31 µmol /L, 13.41- 113.25 µmol /L and 66.54 ± 3.23µmol /L respectively, TS% 47.92 -71.79 and 55.08 ± 1.01, 14.1 - 65.76 and 26.73 ± 2.71 respectively, and serum copper 13.97 - 23.61 µmol /L and 17.99 ± 0.39µmol /L, 7.1 - 16.09 µmol/L and 11.8 ± 0.32 µmol /L respectively. However, a significant (P<0.05) differences between clinically normal and ewes affected with mastitis were recorded in all the measured parameters.The present data records reference ranges and means ± SE of some biochemical parameters in normal lactating and Ovine mastitis with a significant differences between them.

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