The Effect of Long-Term Metabolic Control on Free Thyroid Hormone Levels in Diabetics during Insulin Treatment

1987 ◽  
Vol 24 (5) ◽  
pp. 466-469 ◽  
Author(s):  
J H Parr
Keyword(s):  
Thyroid Hormone ◽  
Metabolic Control ◽  
Insulin Treatment ◽  
Density Lipoprotein ◽  
Hdl Cholesterol ◽  
Hormone Levels ◽  
Free Thyroid Hormone ◽  
The Mean ◽  
Thyroid Hormone Levels

Serum concentration of free T3 and, in female patients, FT4, were found to be lower in 20 asymptomatic, moderately-poor or well controlled, diabetics treated with insulin than in a group of non-diabetic subjects. Over a mean 3-month period of the study a significant fall occurred in HbA1 concentration in both groups of diabetics without change in free thyroid hormone levels. The mean capillary blood glucose, fasting free insulin and fasting lipid concentrations, other than high density lipoprotein (HDL) cholesterol, did not change. No correlations were found between the changes in HbA1 and free thyroid hormone concentrations. Improvement in long term metabolic control did not influence free thyroid hormone levels in well controlled and moderately-poor controlled diabetics, taking insulin.

LRF and TRF test during long-term danazol treatment: increase of the LH and FSH responses but decrease of the prolactin and TSH responses

1983 ◽  
Vol 104 (1) ◽  
pp. 1-5 ◽  
Author(s):  
J. Leppäluoto ◽  
L. Rönnberg ◽  
P. Ylöstalo
Keyword(s):  
Clinical Symptoms ◽  
Follicular Phase ◽  
Blood Samples ◽  
Hormone Levels ◽  
Coefficients Of Variation ◽  
The Mean ◽  
Thyroid Hormone Levels ◽  
Low Serum

Abstract. Seven patients suffering from severe endometriosis were treated with danazol 200 mg × 3 daily for 6 months. Clinical symptoms were alleviated and menses disappeared in response to the treatment. After cessation of the treatment the menstrual bleedings returned in 1–3 months. Blood samples for determination of gonadotrophins, prolactin (Prl), oestradiol (E2), progesterone, thyroid hormones and thyrotrophin in radioimmunoassays were taken and a combined TRF and LRF test carried out in the follicular phase before treatment, at the 6th month of treatment and after reappearance of the first menses. There were no statistically significant changes in the basal levels of serum FSH, LH or TSH during the danazol treatment. Neither was there any change in episodic secretions of FSH, LH or Prl, as determined by the mean coefficients of variation of the hormone levels in seven consecutive samples taken at 20 min intervals. On the other hand, serum E2, Prl and thyroid hormone levels were significantly decreased in the 6th month of treatment. In the TRF-LRF test the responses of serum FSH and LH were significantly higher and those of serum Prl and TSH significantly lower during danazol treatment than before. Prl responses remained lowered after the treatment. It appears that low serum oestrogen levels, induced by the danazol treatment, sensitize the pituitary gonadotrophs to exogenous LRF, but make the sensitivity of thyrotrophs and lactotrophs lower to exogenous TRF. These results thus indicate that danazol does not make the pituitary gonadotrophs insensitive to LRF, but danazol may rather inhibit the secretion of hypothalamic LRF.

Free Fatty Acids: A Possible Regulator of Free Thyroid Hormone Levels in Man1

1967 ◽  
Vol 27 (8) ◽  
pp. 1219-1223 ◽  
Author(s):  
CHARLES S. HOLLANDER ◽  
ROBERT L. SCOTT ◽  
JOHN A. BURGESS ◽  
DAVID RABINOWITZ ◽  
THOMAS J. MERIMEE ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Thyroid Hormone ◽  
Free Fatty Acids ◽  
Hormone Levels ◽  
Free Thyroid Hormone ◽  
Thyroid Hormone Levels

scholarly journals A Brief Exposure to Moderate Passive Smoke Increases Metabolism and Thyroid Hormone Secretion

2007 ◽  
Vol 92 (1) ◽  
pp. 208-211 ◽  
Author(s):  
Giorgos S. Metsios ◽  
Andreas D. Flouris ◽  
Athanasios Z. Jamurtas ◽  
Andres E. Carrillo ◽  
Demetrios Kouretas ◽  
...  
Keyword(s):  
Thyroid Hormone ◽  
Passive Smoking ◽  
Repeated Measures ◽  
Hormone Secretion ◽  
Free T4 ◽  
Hormone Levels ◽  
Urine Cotinine ◽  
The Mean ◽  
Thyroid Hormone Levels ◽  
Serum And Urine

Abstract Context: Active smoking influences normal metabolic status and thyroid function. Objective: The objective was to assess experimentally the effects of 1 h of moderate passive smoking in a controlled simulated bar/restaurant environment on the metabolism and thyroid hormone levels in healthy nonsmokers. Participants: Eighteen (nine females, nine males) healthy individuals (mean ± sd: age, 25.3 ± 3.1 yr; height, 174.0 ± 10.1 cm; weight, 65.2 ± 13.7 kg) participated in the study. Design: In repeated-measures randomized blocks, participants visited the laboratory on 2 consecutive days. In the experimental condition, they were exposed to 1 h of moderate passive smoking at a carbon monoxide concentration of 23 ± 1 ppm in an environmental chamber, whereas in the control condition participants remained in the same chamber for 1 h breathing normal atmospheric air. Main Outcome Measures: In both conditions, cotinine serum and urine levels, resting energy expenditure (REE), as well as concentration of T3, free T4, and TSH were assessed before participants entered the chamber and immediately after their exit. Heart rate and blood pressure were tested in 10-min intervals during all REE assessments. Results: The mean ± sd difference of serum and urine cotinine levels (−0.27 ± 3.94 vs. 14.01 ± 6.54 and 0.05 ± 2.07 vs. 7.23 ± 3.75, respectively), REE (6.73 ± 98.06 vs. 80.58 ± 120.91) as well as T3 and free T4 (0.05 ± 0.11 vs. 0.13 ± 0.12 and 0.02 ± 0.15 vs. 0.22 ± 0.20) were increased in the experimental compared with the control condition at baseline and follow-up (P < 0.05). No statistically significant variation was observed in the mean difference of the remaining parameters (P > 0.05). Serum and urine cotinine values were linearly associated with REE (P < 0.05). Conclusion: One hour of passive smoking at bar/restaurant levels is accompanied by significant increases in metabolism and thyroid hormone levels.

scholarly journals Study of Thyroid Hormone Status in Normal Newborn and Preterm, Low Birth Weight Baby

KYAMC Journal ◽  
2017 ◽  
Vol 7 (2) ◽  
pp. 787-790
Author(s):  
Tanvir Iqbal ◽  
M Obaidulla Ibne Ali ◽  
Nur E Atia ◽  
Tahorul Islam
Keyword(s):  
Birth Weight ◽  
Thyroid Hormone ◽  
Thyroid Gland ◽  
Low Birth Weight ◽  
Newborn Baby ◽  
Preterm Neonates ◽  
Hormone Levels ◽  
Low Birth Weight Babies ◽  
The Mean ◽  
Thyroid Hormone Levels

Background: Screening for thyroid hormones in the newborn baby is extremely important to detect the newborns who are borned with hypofunctional state of thyroid gland. This screening program in first few weeks of life is essential to prevent serious complications of hypothyroidism in future such as mental retardation.Objective: To assess the thyroid hormone levels in normal newborn and preterm, low birth weight babies and comparison of thyroid dysfunction between these two groups.Method: This cross - sectional analytical type of study was conducted in the department of physiology and paediatrics of Rajshahi Medical College & Hospital (RMCH) from July 2015 to June 2016. A total of 70 newborn baby were enrolled by systematic sampling of which 40 were normal healthy newborn and 30 were preterm, low birth weight babies. Data was collected from the parents and they were filled out standard questionnaire. Then venous blood was collected from each and every neonate and blood was sent to laboratory for estimation of thyroid hormone levels. FT4 and TSH values were estimated as these two are the most important parameters for determination of thyroid function.Result: In this study, the mean (±SD) serum FT4 level in term and preterm neonates were 14.17±2.14 and 12.25±3.16 (pg/ml) respectively. This FT4 value is significantly higher in term neonates than preterm neonates (P<0.05). The mean (±SD) serum TSH level in term and preterm neonates were 3.37±2.12 and 4.23±3.23 (?IU/ml) respectively. Statistically there was no significant difference in TSH values between these two groups (P 0.05).Conclusion: From this study it was evident that preterm, low birth weight babies are more likely to develop hypofunctional state of thyroid gland than normal term babies. The newborns who were found hypothyroid, were informed to their parents for consultation with the concerned physicians. The physicians then took necessary steps to correct the hypofunctional state of thyroid gland.KYAMC Journal Vol. 7, No.-2, Jan 2017, Page 787-790

LONG TERM EXPOSURE TO ORGANOCHLORINE PESTICIDES AND THYROID HORMONE LEVELS IN CHILDREN FROM CIDADE DOS MENINOS, RJ, BRAZIL

2011 ◽  
Vol 2011 (1) ◽  
Author(s):  
Carmen Freire ◽  
Rosalina Koifman ◽  
Paula Sarcinelli ◽  
Ana Cristina Rosa ◽  
Ruth Clapauch ◽  
...  
Keyword(s):  
Thyroid Hormone ◽  
Organochlorine Pesticides ◽  
Hormone Levels ◽  
Thyroid Hormone Levels

Effect of Acute Renal Failure on Free Thyroid Hormone Levels in a Thyrotoxic Patient

Nephron ◽  
1989 ◽  
Vol 52 (4) ◽  
pp. 360-362 ◽  
Author(s):  
Michael J. Hardy ◽  
Luiz Nascimento ◽  
Sati Ragbeer ◽  
Samia Bukhari ◽  
Abdulhamid Kashgari
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Thyroid Hormone ◽  
Hormone Levels ◽  
Free Thyroid Hormone ◽  
Thyroid Hormone Levels

Correlation between different degree and duration of metabolic control and thyroid hormone levels in type 1 and type 2 diabetics

1983 ◽  
Vol 20 (4) ◽  
pp. 341-346
Author(s):  
Alberto Notarbartolo ◽  
Giovambattista Rini ◽  
Giuseppe Licata ◽  
Rosario Scaglione ◽  
Gaetana Fede ◽  
...  
Keyword(s):  
Thyroid Hormone ◽  
Metabolic Control ◽  
Hormone Levels ◽  
Type 2 Diabetics ◽  
Thyroid Hormone Levels
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