Numerical simulation of mold filling and particulate flow of A356/SiCp indirect squeeze casting

2016 ◽  
Vol 54 (12) ◽  
pp. 1593-1602
Author(s):  
Qiyao Hu ◽  
Haidong Zhao ◽  
Han Long ◽  
Puyun Dong ◽  
Gang Zhu
Keyword(s):  
Distribution Patterns ◽  
Mold Filling ◽  
Particulate Flow ◽  
Image Analysis System ◽  
Matrix Composites ◽  
Analysis System ◽  
Particulate Distribution ◽  
Particulate Reinforced ◽  
Acceptable Agreement ◽  
Digital Image Analysis System

In this investigation, a mathematical model based on the dispersed phase model and multiphase flow principle was introduced, and applied to simulate the mold filling and particulate flow of particulate reinforced metal matrix composites casting. Experiments of spiral-square shaped indirect squeeze castings of A356/50 µm SiCp were conducted to validate the established model. The SiCp fractions in the casting different locations were quantitatively measured with micro digital image analysis system and were compared with the simulation results. It was found that particulate fractions and distribution patterns at different locations were quite different along the filling distance. The experimental and simulated results about the SiCp distribution in the castings show acceptable agreement. Further, the effect of fluid flow and particulate trajectories on the particulate distribution was analyzed and discussed. The research has shown the validity of application of the model for practical particulate reinforced Al-based composites casting.

Quantitation of the changes in vascularity during arthritis in the knee joint of a mouse with a digital image analysis system

2001 ◽  
Vol 262 (4) ◽  
pp. 420-428 ◽  
Author(s):  
Pieter Buma ◽  
Martin Groenenberg ◽  
Paul F.J.W. Rijken ◽  
Wim B. Van Den Berg ◽  
Leo Joosten ◽  
...  
Keyword(s):  
Image Analysis ◽  
Knee Joint ◽  
Digital Image ◽  
Digital Image Analysis ◽  
Image Analysis System ◽  
Analysis System ◽  
Digital Image Analysis System

scholarly journals Islet Cryopreservation: Improved Recovery following Taurine Pretreatment

2001 ◽  
Vol 10 (3) ◽  
pp. 247-253 ◽  
Author(s):  
Anandwardhan A. Hardikar ◽  
Makarand V. Risbud ◽  
Claude Remacle ◽  
Brigitte Reusens ◽  
Joseph J. Hoet ◽  
...  
Keyword(s):  
Islet Cells ◽  
Radical Scavenging ◽  
The Body ◽  
Control Group ◽  
Image Analysis System ◽  
Islet Mass ◽  
Normal Glucose ◽  
Ethanesulfonic Acid ◽  
Analysis System ◽  
Digital Image Analysis System

Simple and efficient freezing methods with maximal postthawing recovery form the basis of ideal cryopreservation. Taurine (2-amino ethanesulfonic acid), an end-product of sulphur amino acid metabolism, is one of the most abundant free amino acids in the body. The membrane stabilizing, free radical scavenging, and osmoregulatory roles of taurine have been well documented. We studied the effect of physiological and supra-physiological concentrations (0.3 and 3.0 mM) of taurine on islet cryopreservation. Islet viability on cryopreservation was significantly improved in both the taurine-treated groups (91.9 ± 2.3% in 0.3 mM and 94.6 ± 1.58% in 3.0 mM group, p < 0.05) compared with the controls (85.7 ± 3.4%). Loss of peripheral islet cells was highly reduced in the taurine group, as examined under phase contrast and quantified by islet morphometric analysis (p < 0.05) using a digital image analysis system. Taurine-treated islets showed significant reduction in lipid peroxidation (0.905 and 0.848 nM MDA/μg protein for 0.3 and 3.0 mM taurine, respectively, p < 0.05) compared with control (1.307 nM MDA/μg protein) islets. In all, 500 islet equivalents (IE) of treated or control group islets were transplanted to BALB/c mice rendered diabetic with STZ. All animals showed a normal glucose clearance following a glucose load. Graft functionality was confirmed by normoglycemia (fasting plasma glucose: fpg < 150 mg/dl) after transplantation and reappearing hyperglycemia (fpg > 200 mg/dl) following removal of the graft. Suboptimal islet transplantation using 250 IE suggests that the grafted islet mass was inadequate for diabetes reversal. In addition, no significant differences were observed in the islet insulin content between the three groups following cryopreservation of the islets at −196°C. Our studies indicate that taurine pretreatment and its continued presence during islet cryopreservation improves the postthawing viable recovery of islets.

Model-based frequency response characterization of a digital-image analysis system for epifluorescence microscopy

1992 ◽  
Vol 31 (8) ◽  
pp. 1083
Author(s):  
Rajeeb Hazra ◽  
Charles L. Viles ◽  
Stephen K. Park ◽  
Stephen E. Reichenbach ◽  
Michael E. Sieracki
Keyword(s):  
Image Analysis ◽  
Frequency Response ◽  
Digital Image ◽  
Digital Image Analysis ◽  
Epifluorescence Microscopy ◽  
Image Analysis System ◽  
Model Based ◽  
Analysis System ◽  
Digital Image Analysis System
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