Fever of Unknown Origin: A Prospective Study

1996 ◽  
Vol 26 (4) ◽  
pp. 169-170 ◽  
Author(s):  
R Handa ◽  
S Singh ◽  
N Singh ◽  
J P Wali

Fever of unknown origin (FUO) is a problem frequently faced by clinicians all over the world. One hundred and twenty-one cases of FUO presenting to a large teaching hospital in northern India were prospectively studied over a period of 2 years. Infections were the commonest cause accounting for 43.8% cases of FUO, with tuberculosis (TB) being the commonest infection encountered. Collagen vascular diseases and tumours accounted for 15.7 and 8.3% cases, respectively. No cause could be found out in a substantial number of cases (19%) even after invasive investigations. Knowledge of the current patterns of FUO is important since many patients present with potentially treatable diseases.

2003 ◽  
Vol 124 (4) ◽  
pp. A352
Author(s):  
Fabrizio Parente ◽  
Claudia Cucino ◽  
Stefano Bargiggia ◽  
Salvatore Greco ◽  
Luca Pastore ◽  
...  

2016 ◽  
Vol 10 (01) ◽  
pp. 30-42 ◽  
Author(s):  
Ahmed F Kabapy ◽  
Amira M Kotkat ◽  
Hanan Zakaria Shatat ◽  
Ekram W Abd El Wahab

Introduction: Fever of unknown origin (FUO) is one of the most challenging diagnostic dilemmas in the field of infectious diseases and tropical medicine. Clinicians should use the frequency distribution of disorders causing FUO to guide their diagnostic approach in patients with prolonged, unexplained fevers meeting the definition of FUO. Methodology: The present study was undertaken to examine the etiologies, clinico-epidemiologic profile, and prognosis of classical FUO in patients reporting to the Alexandria Fever Hospital in Egypt. Records of 979 patients admitted to the fever hospital (from January 2009 to January 2010) and diagnosed as having FUO were examined carefully. FUO was defined as three outpatient visits or three days in the hospital without elucidation of cause of fever. Results: A total of 979 cases (57.0% males and 43.0% females), with ages ranging from 0.2 to 90 years, were investigated. The mean duration of fever before hospitalization was 31 ± 10 days. The etiology of FUO was delineated in 97% of cases, and only 3% remained undiagnosed. Diagnoses were grouped into five major categories. Infectious causes of FUO were strongly associated with better outcome (73.7% improved). Smoking, contact with animals or birds, drug addiction, and HIV seropositivity were important risk factors associated with infections. Conclusions: Infections are the most common cause of FUO, followed by collagen vascular diseases, in our region. A three-step diagnostic work-up approach is recommended to be applied in Egypt in order to improve the quality of medical service provided to FUO patients.


HPB Surgery ◽  
1990 ◽  
Vol 3 (1) ◽  
pp. 5-10 ◽  
Author(s):  
Julio A. Diez ◽  
M. Raúl Pujato ◽  
Alberto R. Ferreres

In an attempt to rationalize the use of intraperitoneal drainage of the subhepatic space after simple, elective cholecystectomy, a prospective study was designed to compare the post-operative course with and without drainage. There was a higher incidence of postoperative fever of unknown origin and wound infection in the drained group. In the group without drainage the hospital postoperative stay was shorter and there were no complications. The results suggest that routine surgical drainage after uncomplicated cholecystectomy is unnecessary and could be a source of postoperative fever and a higher incidence of wound infection.


2010 ◽  
Vol 36 (1) ◽  
pp. 26-35 ◽  
Author(s):  
Dhia J. Al-Layla ◽  
Humam Ghanim ◽  
A Rafe ◽  
H. Al-Kazzaz ◽  
Rami M. A. Al-Hayali

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